Publications

The FEBS journal

Targeting dormant tumor cells to prevent cancer recurrence.

01-11-2021

Oncogene

Regulation of a progenitor gene program by SOX4 is essential for mammary tumor proliferation.

01-11-2021

Nature reviews. Cancer

Tissue clearing to examine tumour complexity in three dimensions.

01-11-2021

The EMBO journal

RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis.

18-10-2021

Current opinion in cell biology

Intravital microscopy to illuminate cell state plasticity during metastasis.

01-10-2021

Oncotarget

Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing.

17-08-2021

Cell reports

Active elimination of intestinal cells drives oncogenic growth in organoids.

06-07-2021

Journal of clinical medicine

Epithelial-to-Mesenchymal Transition in the Light of Plasticity and Hybrid E/M States.

29-05-2021

eLife

Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer.

26-05-2021

Cells

Resistance of Hypoxic Cells to Ionizing Radiation Is Mediated in Part via Hypoxia-Induced Quiescence.

10-03-2021

Journal of mammary gland biology and neoplasia

An Intravital Microscopy Toolbox to Study Mammary Gland Dynamics from Cellular Level to Organ Scale.

01-03-2021

Genome biology

A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis.

29-01-2021

Life science alliance

Scratch-induced partial skin wounds re-epithelialize by sheets of independently migrating keratinocytes.

01-01-2021

Nature protocols

Antigen retrieval and clearing for whole-organ immunofluorescence by FLASH.

01-01-2021

Cold Spring Harbor perspectives in medicine

Cellular Plasticity during Metastasis: New Insights Provided by Intravital Microscopy.

02-11-2020

Oncogene

An unanticipated tumor-suppressive role of the SUMO pathway in the intestine unveiled by Ubc9 haploinsufficiency.

01-10-2020

Current biology : CB

How the COVID-19 pandemic highlights the necessity of animal research.

21-09-2020

Cold Spring Harbor perspectives in biology

Capturing Stem Cell Behavior Using Intravital and Live Cell Microscopy.

01-09-2020

Cell reports

Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine.

21-07-2020

Proceedings of the National Academy of Sciences of the United States of America

Stem cell lineage survival as a noisy competition for niche access.

21-07-2020

Nature cancer

Publisher Correction: Long-distance modulation of bystander tumor cells by CD8⁺ T-cell-secreted IFN-γ.

01-07-2020

Cell stem cell

Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer.

02-04-2020

Key Publication

Clinical & experimental metastasis

Poor perfusion of the microvasculature in peritoneal metastases of ovarian cancer.

01-04-2020

Nature communications

Publisher Correction: A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA.

31-03-2020

Nature cancer

Long-distance modulation of bystander tumor cells by CD8⁺ T cell-secreted IFNγ.

01-03-2020

Nature communications

A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA.

28-02-2020

Nature communications

C/EBPɑ is crucial determinant of epithelial maintenance by preventing epithelial-to-mesenchymal transition.

07-02-2020

Cell reports

Fsp1-Mediated Lineage Tracing Fails to Detect the Majority of Disseminating Cells Undergoing EMT.

26-11-2019

Nature communications

Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin.

23-08-2019

Cell stem cell

Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids.

06-06-2019

Scientific reports

Intravital imaging of glioma border morphology reveals distinctive cellular dynamics and contribution to tumor cell invasion.

14-02-2019

The EMBO journal

Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles.

01-08-2018

Journal of extracellular vesicles

Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8.

27-04-2018

Clinical & experimental metastasis

Potential impact of invasive surgical procedures on primary tumor growth and metastasis.

01-04-2018

Nature communications

Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells.

19-03-2018

The Journal of cell biology

Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling.

05-03-2018

Nature protocols

A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression.

01-02-2018

Swiss medical weekly

Cellular protection mechanisms that minimise accumulation of mutations in intestinal tissue.

10-11-2017

Intravital

Intravital characterization of tumor cell migration in pancreatic cancer.

01-03-2017

Cell

A Vulnerability of a Subset of Colon Cancers with Potential Clinical Utility.

07-04-2016

Cell reports

Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity.

15-03-2016

PloS one

Intravital FRET imaging of tumor cell viability and mitosis during chemotherapy.

22-05-2013

Proceedings of the National Academy of Sciences of the United States of America

Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen.

27-11-2012

Experimental cell research

Investigation into the mechanism regulating MRP localization.

15-01-2008

Molecular biology of the cell

Serine phosphorylation of the integrin beta4 subunit is necessary for epidermal growth factor receptor induced hemidesmosome disruption.

01-09-2007

BMC biotechnology

Intravital imaging of fluorescent markers and FRET probes by DNA tattooing.

03-01-2007

Current biology : CB

A role for PtdIns(4,5)P2 and PIP5Kalpha in regulating stress-induced apoptosis.

19-09-2006

Journal of cellular physiology

Integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the ROCK-I kinase at the plasma membrane.

01-09-2006

The Journal of cell biology

Integrins control motile strategy through a Rho-cofilin pathway.

09-05-2005

The EMBO journal

PIP2 signaling in lipid domains: a critical re-evaluation.

04-05-2005

Targeting dormant tumor cells to prevent cancer recurrence.

Regulation of a progenitor gene program by SOX4 is essential for mammary tumor proliferation.

Tissue clearing to examine tumour complexity in three dimensions.

RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis.

Intravital microscopy to illuminate cell state plasticity during metastasis.

Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing.

Active elimination of intestinal cells drives oncogenic growth in organoids.

Epithelial-to-Mesenchymal Transition in the Light of Plasticity and Hybrid E/M States.

Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer.

Resistance of Hypoxic Cells to Ionizing Radiation Is Mediated in Part via Hypoxia-Induced Quiescence.

An Intravital Microscopy Toolbox to Study Mammary Gland Dynamics from Cellular Level to Organ Scale.

A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis.

Scratch-induced partial skin wounds re-epithelialize by sheets of independently migrating keratinocytes.

Antigen retrieval and clearing for whole-organ immunofluorescence by FLASH.

Cellular Plasticity during Metastasis: New Insights Provided by Intravital Microscopy.

An unanticipated tumor-suppressive role of the SUMO pathway in the intestine unveiled by Ubc9 haploinsufficiency.

How the COVID-19 pandemic highlights the necessity of animal research.

Capturing Stem Cell Behavior Using Intravital and Live Cell Microscopy.

Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine.

Stem cell lineage survival as a noisy competition for niche access.

Publisher Correction: Long-distance modulation of bystander tumor cells by CD8+ T-cell-secreted IFN-γ.

Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer.

Poor perfusion of the microvasculature in peritoneal metastases of ovarian cancer.

Publisher Correction: A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA.

Long-distance modulation of bystander tumor cells by CD8+ T cell-secreted IFNγ.

A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA.

C/EBPɑ is crucial determinant of epithelial maintenance by preventing epithelial-to-mesenchymal transition.

Fsp1-Mediated Lineage Tracing Fails to Detect the Majority of Disseminating Cells Undergoing EMT.

Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin.

Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids.

Intravital imaging of glioma border morphology reveals distinctive cellular dynamics and contribution to tumor cell invasion.

Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles.

Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8.

Potential impact of invasive surgical procedures on primary tumor growth and metastasis.

Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells.

Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling.

A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression.

Cellular protection mechanisms that minimise accumulation of mutations in intestinal tissue.

Intravital characterization of tumor cell migration in pancreatic cancer.

A Vulnerability of a Subset of Colon Cancers with Potential Clinical Utility.

Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity.

Intravital FRET imaging of tumor cell viability and mitosis during chemotherapy.

Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen.

Investigation into the mechanism regulating MRP localization.

Serine phosphorylation of the integrin beta4 subunit is necessary for epidermal growth factor receptor induced hemidesmosome disruption.

Intravital imaging of fluorescent markers and FRET probes by DNA tattooing.

A role for PtdIns(4,5)P2 and PIP5Kalpha in regulating stress-induced apoptosis.

Integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the ROCK-I kinase at the plasma membrane.

Integrins control motile strategy through a Rho-cofilin pathway.

PIP2 signaling in lipid domains: a critical re-evaluation.

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Publisher Correction: Long-distance modulation of bystander tumor cells by CD8⁺ T-cell-secreted IFN-γ.

Long-distance modulation of bystander tumor cells by CD8⁺ T cell-secreted IFNγ.