Publications

Cell reports

Active elimination of intestinal cells drives oncogenic growth in organoids.

06-07-2021

Journal of clinical medicine

Epithelial-to-Mesenchymal Transition in the Light of Plasticity and Hybrid E/M States.

29-05-2021

eLife

Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer.

26-05-2021

Cells

Resistance of Hypoxic Cells to Ionizing Radiation Is Mediated in Part via Hypoxia-Induced Quiescence.

10-03-2021

Journal of mammary gland biology and neoplasia

An Intravital Microscopy Toolbox to Study Mammary Gland Dynamics from Cellular Level to Organ Scale.

01-03-2021

Genome biology

A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis.

29-01-2021

Life science alliance

Scratch-induced partial skin wounds re-epithelialize by sheets of independently migrating keratinocytes.

01-01-2021

Nature protocols

Antigen retrieval and clearing for whole-organ immunofluorescence by FLASH.

01-01-2021

Cold Spring Harbor perspectives in medicine

Cellular Plasticity during Metastasis: New Insights Provided by Intravital Microscopy.

02-11-2020

Oncogene

An unanticipated tumor-suppressive role of the SUMO pathway in the intestine unveiled by Ubc9 haploinsufficiency.

01-10-2020

Current biology : CB

How the COVID-19 pandemic highlights the necessity of animal research.

21-09-2020

Cold Spring Harbor perspectives in biology

Capturing Stem Cell Behavior Using Intravital and Live Cell Microscopy.

01-09-2020

Cell reports

Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine.

21-07-2020

Proceedings of the National Academy of Sciences of the United States of America

Stem cell lineage survival as a noisy competition for niche access.

21-07-2020

Nature cancer

Publisher Correction: Long-distance modulation of bystander tumor cells by CD8⁺ T-cell-secreted IFN-γ.

01-07-2020

Cell stem cell

Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer.

02-04-2020

Key

Clinical & experimental metastasis

Poor perfusion of the microvasculature in peritoneal metastases of ovarian cancer.

01-04-2020

Nature communications

Publisher Correction: A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA.

31-03-2020

Nature cancer

Long-distance modulation of bystander tumor cells by CD8⁺ T cell-secreted IFNγ.

01-03-2020

Nature communications

A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA.

28-02-2020

Nature communications

C/EBPɑ is crucial determinant of epithelial maintenance by preventing epithelial-to-mesenchymal transition.

07-02-2020

Cell reports

Fsp1-Mediated Lineage Tracing Fails to Detect the Majority of Disseminating Cells Undergoing EMT.

26-11-2019

Nature communications

Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin.

23-08-2019

Cell stem cell

Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids.

06-06-2019

Scientific reports

Intravital imaging of glioma border morphology reveals distinctive cellular dynamics and contribution to tumor cell invasion.

14-02-2019

The EMBO journal

Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles.

01-08-2018

Journal of extracellular vesicles

Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8.

27-04-2018

Clinical & experimental metastasis

Potential impact of invasive surgical procedures on primary tumor growth and metastasis.

01-04-2018

Nature communications

Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells.

19-03-2018

The Journal of cell biology

Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling.

05-03-2018

Nature protocols

A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression.

01-02-2018

Swiss medical weekly

Cellular protection mechanisms that minimise accumulation of mutations in intestinal tissue.

10-11-2017

Intravital

Intravital characterization of tumor cell migration in pancreatic cancer.

01-03-2017

Cell

A Vulnerability of a Subset of Colon Cancers with Potential Clinical Utility.

07-04-2016

Cell reports

Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity.

15-03-2016

PloS one

Intravital FRET imaging of tumor cell viability and mitosis during chemotherapy.

22-05-2013

Proceedings of the National Academy of Sciences of the United States of America

Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen.

27-11-2012

Experimental cell research

Investigation into the mechanism regulating MRP localization.

15-01-2008

Molecular biology of the cell

Serine phosphorylation of the integrin beta4 subunit is necessary for epidermal growth factor receptor induced hemidesmosome disruption.

01-09-2007

BMC biotechnology

Intravital imaging of fluorescent markers and FRET probes by DNA tattooing.

03-01-2007

Current biology : CB

A role for PtdIns(4,5)P2 and PIP5Kalpha in regulating stress-induced apoptosis.

19-09-2006

Journal of cellular physiology

Integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the ROCK-I kinase at the plasma membrane.

01-09-2006

The Journal of cell biology

Integrins control motile strategy through a Rho-cofilin pathway.

09-05-2005

The EMBO journal

PIP2 signaling in lipid domains: a critical re-evaluation.

04-05-2005

Biophysical journal

Correcting confocal acquisition to optimize imaging of fluorescence resonance energy transfer by sensitized emission.

01-04-2004

Molecular biology of the cell

Agonist-induced PIP(2) hydrolysis inhibits cortical actin dynamics: regulation at a global but not at a micrometer scale.

01-09-2002