Publications

Nature biotechnology

A single-chain derivative of an integrin-activating antibody potentiates organoid growth in Matrigel and collagen hydrogels.

28-10-2025

Scientific reports

Colorectal carcinoma progression is not influenced by the pseudokinase PEAK1.

12-11-2024

Journal of cell science

Caskin2 is a novel talin- and Abi1-binding protein that promotes cell motility.

01-05-2024

The Journal of cell biology

PEAK1 Y635 phosphorylation regulates cell migration through association with Tensin3 and integrins.

01-08-2022

Journal of cell science

Molecular determinants of αVβ5 localization in flat clathrin lattices - role of αVβ5 in cell adhesion and proliferation.

01-06-2022

Journal of cell science

The laminin-binding integrins regulate nuclear factor κB-dependent epithelial cell polarity and inflammation.

15-12-2021

Journal of cell science

Regulation of hemidesmosome dynamics and cell signaling by integrin α6β4.

15-09-2021

Scientific reports

EGFR-dependent tyrosine phosphorylation of integrin β4 is not required for downstream signaling events in cancer cell lines.

21-04-2021

The Journal of investigative dermatology

Integrin α3β1 Is a Key Regulator of Several Protumorigenic Pathways during Skin Carcinogenesis.

01-04-2021

BioEssays : news and reviews in molecular, cellular and developmental biology

Crosstalk between Cell Adhesion Complexes in Regulation of Mechanotransduction.

01-11-2020

Matrix biology : journal of the International Society for Matrix Biology

Reciprocal integrin/integrin antagonism through kindlin-2 and Rho GTPases regulates cell cohesion and collective migration.

01-11-2020

Biology open

Comparative interactomics analysis reveals potential regulators of α6β4 distribution in keratinocytes.

13-08-2020

Life science alliance

Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis.

01-07-2020

Development (Cambridge, England)

Laminin-binding integrins are essential for the maintenance of functional mammary secretory epithelium in lactation.

17-02-2020

The Journal of cell biology

Hemidesmosomes modulate force generation via focal adhesions.

03-02-2020

Nature communications

Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin.

23-08-2019

Breast cancer research : BCR

Absence of integrin α3β1 promotes the progression of HER2-driven breast cancer in vivo.

17-05-2019

The Journal of biological chemistry

The Structure of the Plakin Domain of Plectin Reveals an Extended Rod-like Shape.

02-09-2016

Methods in enzymology

Preface.

19-01-2016

Molecular biology of the cell

The rod domain is not essential for the function of plectin in maintaining tissue integrity.

01-07-2015

Molecular biology of the cell

Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt.

15-05-2015

Acta crystallographica. Section D, Biological crystallography

Combination of X-ray crystallography, SAXS and DEER to obtain the structure of the FnIII-3,4 domains of integrin α6β4.

01-04-2015

Oncogene

Dual roles of hemidesmosomal proteins in the pancreatic epithelium: the phosphoinositide 3-kinase decides.

10-04-2014

The Journal of investigative dermatology

Kindlin-1 mutant zebrafish as an in vivo model system to study adhesion mechanisms in the epidermis.

01-09-2013

PloS one

Kindlin-1 regulates integrin dynamics and adhesion turnover.

19-06-2013

Nature reviews. Nephrology

Cell-matrix adhesion of podocytes in physiology and disease.

01-04-2013

Cellular and molecular life sciences : CMLS

MAPK uncouples cell cycle progression from cell spreading and cytoskeletal organization in cycling cells.

01-01-2013

The Journal of biological chemistry

Epigenetic regulation of galectin-3 expression by β1 integrins promotes cell adhesion and migration.

28-12-2012

Proceedings of the National Academy of Sciences of the United States of America

Loss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cells.

26-12-2012

Current biology : CB

Distinct roles of talin and kindlin in regulating integrin α5β1 function and trafficking.

11-09-2012

PloS one

Carbonic anhydrase 5 regulates acid-base homeostasis in zebrafish.

30-06-2012

Molecular biology of the cell

Phosphorylation of threonine 1736 in the C-terminal tail of integrin β4 contributes to hemidesmosome disassembly.

01-04-2012

Biochemical Society transactions

Nesprin-3: a versatile connector between the nucleus and the cytoskeleton.

01-12-2011

Current opinion in cell biology

Mechanisms of integrin activation and trafficking.

01-10-2011

The Journal of biological chemistry

EGF-induced MAPK signaling inhibits hemidesmosome formation through phosphorylation of the integrin {beta}4.

26-11-2010

The Journal of investigative dermatology

Expression of the orphan protein Plet-1 during trichilemmal differentiation of anagen hair follicles.

01-06-2010

Journal of cell science

Integrin alpha3beta1 inhibits directional migration and wound re-epithelialization in the skin.

15-01-2009

Current opinion in cell biology

Regulation of hemidesmosome disassembly by growth factor receptors.

01-10-2008

Experimental cell research

Investigation into the mechanism regulating MRP localization.

15-01-2008

Molecular biology of the cell

Dual Role of alpha6beta4 integrin in epidermal tumor growth: tumor-suppressive versus tumor-promoting function.

01-11-2007

Journal of cell science

Requirements for the localization of nesprin-3 at the nuclear envelope and its interaction with plectin.

01-10-2007

Molecular biology of the cell

Serine phosphorylation of the integrin beta4 subunit is necessary for epidermal growth factor receptor induced hemidesmosome disruption.

01-09-2007

Journal of molecular biology

The structure of a tandem pair of spectrin repeats of plectin reveals a modular organization of the plakin domain.

18-05-2007

Experimental cell research

The regulation of MacMARCKS expression by integrin beta3.

01-04-2007

Cancer research

Integrin alpha v beta 3 controls activity and oncogenic potential of primed c-Src.

15-03-2007

Trends in cell biology

Current insights into the formation and breakdown of hemidesmosomes.

01-07-2006

Molecular and cellular biology

Multiple functions of the integrin alpha6beta4 in epidermal homeostasis and tumorigenesis.

01-04-2006

The Journal of cell biology

The Rac activator Tiam1 is required for (alpha)3(beta)1-mediated laminin-5 deposition, cell spreading, and cell migration.

05-12-2005

The Journal of biological chemistry

Modeling and experimental validation of the binary complex of the plectin actin-binding domain and the first pair of fibronectin type III (FNIII) domains of the beta4 integrin.

10-06-2005

Journal of cell science

Keratinocytes display normal proliferation, survival and differentiation in conditional beta4-integrin knockout mice.

01-03-2005