Publications

EMBO reports

The phosphatase inhibitor LB-100 creates neoantigens in colon cancer cells through perturbation of mRNA splicing.

10-04-2024

Cancer cell

Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness.

08-04-2024

The Journal of experimental medicine

MYC is a clinically significant driver of mTOR inhibitor resistance in breast cancer.

06-11-2023

BMC cancer

ABPEPserver: a web application for documentation and analysis of substitutants.

03-06-2023

Cell reports. Medicine

An adverse tumor-protective effect of IDO1 inhibition.

21-02-2023

Molecular cell

Proteome diversification by mRNA translation in cancer.

02-02-2023

Trends in genetics : TIG

Slippy-Sloppy translation: a tale of programmed and induced-ribosomal frameshifting.

01-11-2022

Molecular cell

Alternative cleavage and polyadenylation generates downstream uncapped RNA isoforms with translation potential.

20-10-2022

Cancer research

Boosting Antitumor Immunity with an Expanded Neoepitope Landscape.

17-10-2022

Nature communications

Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers.

05-08-2022

Nature

Author Correction: Tryptophan depletion results in tryptophan-to-phenylalanine substitutants.

01-08-2022

Oncogene

Suppression of heparan sulfation re-sensitizes YAP1-driven melanoma to MAPK pathway inhibitors.

01-08-2022

Nature

Tryptophan depletion results in tryptophan-to-phenylalanine substitutants.

01-03-2022

Molecular cell

Oncogene-dependent sloppiness in mRNA translation.

18-11-2021

Nature

Anti-tumour immunity induces aberrant peptide presentation in melanoma.

01-02-2021

Genome biology

A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis.

29-01-2021

Molecular systems biology

Proteomic patterns associated with response to breast cancer neoadjuvant treatment.

01-09-2020

Molecular cell

Transcription Dynamics Regulate Poly(A) Tails and Expression of the RNA Degradation Machinery to Balance mRNA Levels.

07-05-2020

The EMBO journal

More or less - the same? mRNA fluctuations are balanced during translation.

02-12-2019

Nucleic acids research

A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation.

10-10-2019

The EMBO journal

SLC1A3 contributes to L-asparaginase resistance in solid tumors.

04-10-2019

Bioorganic & medicinal chemistry letters

A fragment-like approach to PYCR1 inhibition.

15-09-2019

Cell

SCAF4 and SCAF8, mRNA Anti-Terminator Proteins.

13-06-2019

Nature communications

Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells.

11-06-2019

Cancer letters

CUEDC1 is a primary target of ERα essential for the growth of breast cancer cells.

01-11-2018

The EMBO journal

Queuing up the ribosome: nutrition and the microbiome control protein synthesis.

14-09-2018

Genome biology

Functional CRISPR screen identifies AP1-associated enhancer regulating FOXF1 to modulate oncogene-induced senescence.

17-08-2018

Nucleic acids research

LncRNA-OIS1 regulates DPP4 activation to modulate senescence induced by RAS.

04-05-2018

Cancer metastasis reviews

Long non-coding RNAs in metastasis.

01-03-2018

Nature communications

FcαRI co-stimulation converts human intestinal CD103⁺ dendritic cells into pro-inflammatory cells through glycolytic reprogramming.

28-02-2018

Wellcome open research

Using mitoribosomal profiling to investigate human mitochondrial translation.

02-02-2018

Nucleic acids research

Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair.

25-01-2018

Oncotarget

The methylated way to translation.

07-11-2017

Nature biotechnology

Characterization of noncoding regulatory DNA in the human genome.

08-08-2017

Cell

Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation.

06-04-2017

EMBO reports

TGFβ1-induced leucine limitation uncovered by differential ribosome codon reading.

01-04-2017

Methods in molecular biology (Clifton, N.J.)

GRO-seq, A Tool for Identification of Transcripts Regulating Gene Expression.

30-03-2017

Oncogene

microRNAs with AAGUGC seed motif constitute an integral part of an oncogenic signaling network.

09-02-2017

Nature reviews. Molecular cell biology

Applying CRISPR-Cas9 tools to identify and characterize transcriptional enhancers.

01-09-2016

Cell cycle (Georgetown, Tex.)

Monitoring amino acid deficiencies in cancer.

01-09-2016

Oncogene

A p53-bound enhancer region controls a long intergenic noncoding RNA required for p53 stress response.

18-08-2016

Nature

Tumour-specific proline vulnerability uncovered by differential ribosome codon reading.

25-02-2016

Circulation research

Genome-Wide Polyadenylation Maps Reveal Dynamic mRNA 3'-End Formation in the Failing Human Heart.

05-02-2016

PLoS genetics

3'UTR Shortening Potentiates MicroRNA-Based Repression of Pro-differentiation Genes in Proliferating Human Cells.

01-02-2016

Nature biotechnology

Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9.

01-02-2016

EMBO reports

Myc coordinates transcription and translation to enhance transformation and suppress invasiveness.

01-12-2015

The international journal of biochemistry & cell biology

Exposure to arginine analog canavanine induces aberrant mitochondrial translation products, mitoribosome stalling, and instability of the mitochondrial proteome.

01-08-2015

Expert opinion on biological therapy

Enhancer-associated RNAs as therapeutic targets.

01-05-2015

Nature communications

Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA.

27-03-2015

Molecular cell

Transcription initiation determines its end.

22-01-2015