Publications

Cancer research

Arginine Deprivation of ASS1-Deficient Cancers Drives Mistranslation and Shared Neoepitope Production.

15-07-2026

Cell death discovery

Histidine to glutamine substitutants, a regulated process that impacts cell survival and suggests histidine shortage in cancer.

27-06-2026

Hepatology (Baltimore, Md.)

Aspartyl-tRNA synthetase 1 (DARS1) reshapes hepatocellular carcinoma proteome and promotes aggressiveness through noncanonical SAGA-MYC signaling modulation.

06-03-2026

Communications biology

MHC1-TIP enables single-tube multimodal immunopeptidome profiling and uncovers intratumoral heterogeneity in antigen presentation.

22-01-2026

NAR cancer

Exploiting nanopore sequencing advances for tRNA sequencing of human cancer models.

01-12-2025

Nature communications

Upstream open reading frame translation enhances immunogenic peptide presentation in mitotically arrested cancer cells.

27-08-2025

bioRxiv : the preprint server for biology

Identification of RNA binding proteins that mediate a quality control mechanism of splicing.

23-07-2025

bioRxiv : the preprint server for biology

MHC1-TIP enables single-tube multimodal immunopeptidome profiling and uncovers intratumoral heterogeneity in antigen presentation.

21-07-2025

Immunity

Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation.

14-01-2025

Nucleic acids research

Chemotherapeutic agents and leucine deprivation induce codon-biased aberrant protein production in cancer.

11-12-2024

Nature cell biology

Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma.

01-07-2024

Cell reports

Gene and protein sequence features augment HLA class I ligand predictions.

25-06-2024

Oncogene

Molecular mechanisms of non-genetic aberrant peptide production in cancer.

01-06-2024

Science (New York, N.Y.)

DNA damage induces p53-independent apoptosis through ribosome stalling.

17-05-2024

Molecular cell

Arginine deprivation enriches lung cancer proteomes with cysteine by inducing arginine-to-cysteine substitutants.

16-05-2024

EMBO reports

The phosphatase inhibitor LB-100 creates neoantigens in colon cancer cells through perturbation of mRNA splicing.

01-05-2024

Cancer cell

Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness.

08-04-2024

The Journal of experimental medicine

MYC is a clinically significant driver of mTOR inhibitor resistance in breast cancer.

06-11-2023

BMC cancer

ABPEPserver: a web application for documentation and analysis of substitutants.

03-06-2023

Cell reports. Medicine

An adverse tumor-protective effect of IDO1 inhibition.

21-02-2023

Molecular cell

Proteome diversification by mRNA translation in cancer.

02-02-2023

Trends in genetics : TIG

Slippy-Sloppy translation: a tale of programmed and induced-ribosomal frameshifting.

01-11-2022

Molecular cell

Alternative cleavage and polyadenylation generates downstream uncapped RNA isoforms with translation potential.

20-10-2022

Cancer research

Boosting Antitumor Immunity with an Expanded Neoepitope Landscape.

17-10-2022

Nature communications

Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers.

05-08-2022

Nature

Author Correction: Tryptophan depletion results in tryptophan-to-phenylalanine substitutants.

01-08-2022

Oncogene

Suppression of heparan sulfation re-sensitizes YAP1-driven melanoma to MAPK pathway inhibitors.

01-08-2022

Nature

Tryptophan depletion results in tryptophan-to-phenylalanine substitutants.

01-03-2022

Molecular cell

Oncogene-dependent sloppiness in mRNA translation.

18-11-2021

Nature

Anti-tumour immunity induces aberrant peptide presentation in melanoma.

01-02-2021

Genome biology

A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis.

29-01-2021

Molecular systems biology

Proteomic patterns associated with response to breast cancer neoadjuvant treatment.

01-09-2020

Molecular cell

Transcription Dynamics Regulate Poly(A) Tails and Expression of the RNA Degradation Machinery to Balance mRNA Levels.

07-05-2020

The EMBO journal

More or less - the same? mRNA fluctuations are balanced during translation.

02-12-2019

Nucleic acids research

A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation.

10-10-2019

The EMBO journal

SLC1A3 contributes to L-asparaginase resistance in solid tumors.

04-10-2019

Bioorganic & medicinal chemistry letters

A fragment-like approach to PYCR1 inhibition.

15-09-2019

Cell

SCAF4 and SCAF8, mRNA Anti-Terminator Proteins.

13-06-2019

Nature communications

Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells.

11-06-2019

Cancer letters

CUEDC1 is a primary target of ERα essential for the growth of breast cancer cells.

01-11-2018

The EMBO journal

Queuing up the ribosome: nutrition and the microbiome control protein synthesis.

14-09-2018

Genome biology

Functional CRISPR screen identifies AP1-associated enhancer regulating FOXF1 to modulate oncogene-induced senescence.

17-08-2018

Nucleic acids research

LncRNA-OIS1 regulates DPP4 activation to modulate senescence induced by RAS.

04-05-2018

Cancer metastasis reviews

Long non-coding RNAs in metastasis.

01-03-2018

Nature communications

FcαRI co-stimulation converts human intestinal CD103⁺ dendritic cells into pro-inflammatory cells through glycolytic reprogramming.

28-02-2018

Wellcome open research

Using mitoribosomal profiling to investigate human mitochondrial translation.

02-02-2018

Nucleic acids research

Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair.

25-01-2018

Oncotarget

The methylated way to translation.

07-11-2017

Nature biotechnology

Characterization of noncoding regulatory DNA in the human genome.

08-08-2017

Cell

Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation.

06-04-2017

Arginine Deprivation of ASS1-Deficient Cancers Drives Mistranslation and Shared Neoepitope Production.

Histidine to glutamine substitutants, a regulated process that impacts cell survival and suggests histidine shortage in cancer.

Aspartyl-tRNA synthetase 1 (DARS1) reshapes hepatocellular carcinoma proteome and promotes aggressiveness through noncanonical SAGA-MYC signaling modulation.

MHC1-TIP enables single-tube multimodal immunopeptidome profiling and uncovers intratumoral heterogeneity in antigen presentation.

Exploiting nanopore sequencing advances for tRNA sequencing of human cancer models.

Upstream open reading frame translation enhances immunogenic peptide presentation in mitotically arrested cancer cells.

Identification of RNA binding proteins that mediate a quality control mechanism of splicing.

MHC1-TIP enables single-tube multimodal immunopeptidome profiling and uncovers intratumoral heterogeneity in antigen presentation.

Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation.

Chemotherapeutic agents and leucine deprivation induce codon-biased aberrant protein production in cancer.

Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma.

Gene and protein sequence features augment HLA class I ligand predictions.

Molecular mechanisms of non-genetic aberrant peptide production in cancer.

DNA damage induces p53-independent apoptosis through ribosome stalling.

Arginine deprivation enriches lung cancer proteomes with cysteine by inducing arginine-to-cysteine substitutants.

The phosphatase inhibitor LB-100 creates neoantigens in colon cancer cells through perturbation of mRNA splicing.

Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness.

MYC is a clinically significant driver of mTOR inhibitor resistance in breast cancer.

ABPEPserver: a web application for documentation and analysis of substitutants.

An adverse tumor-protective effect of IDO1 inhibition.

Proteome diversification by mRNA translation in cancer.

Slippy-Sloppy translation: a tale of programmed and induced-ribosomal frameshifting.

Alternative cleavage and polyadenylation generates downstream uncapped RNA isoforms with translation potential.

Boosting Antitumor Immunity with an Expanded Neoepitope Landscape.

Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers.

Author Correction: Tryptophan depletion results in tryptophan-to-phenylalanine substitutants.

Suppression of heparan sulfation re-sensitizes YAP1-driven melanoma to MAPK pathway inhibitors.

Tryptophan depletion results in tryptophan-to-phenylalanine substitutants.

Oncogene-dependent sloppiness in mRNA translation.

Anti-tumour immunity induces aberrant peptide presentation in melanoma.

A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis.

Proteomic patterns associated with response to breast cancer neoadjuvant treatment.

Transcription Dynamics Regulate Poly(A) Tails and Expression of the RNA Degradation Machinery to Balance mRNA Levels.

More or less - the same? mRNA fluctuations are balanced during translation.

A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation.

SLC1A3 contributes to L-asparaginase resistance in solid tumors.

A fragment-like approach to PYCR1 inhibition.

SCAF4 and SCAF8, mRNA Anti-Terminator Proteins.

Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells.

CUEDC1 is a primary target of ERα essential for the growth of breast cancer cells.

Queuing up the ribosome: nutrition and the microbiome control protein synthesis.

Functional CRISPR screen identifies AP1-associated enhancer regulating FOXF1 to modulate oncogene-induced senescence.

LncRNA-OIS1 regulates DPP4 activation to modulate senescence induced by RAS.

Long non-coding RNAs in metastasis.

FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming.

Using mitoribosomal profiling to investigate human mitochondrial translation.

Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair.

The methylated way to translation.

Characterization of noncoding regulatory DNA in the human genome.

Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation.

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FcαRI co-stimulation converts human intestinal CD103⁺ dendritic cells into pro-inflammatory cells through glycolytic reprogramming.