Publications

Nature genetics

Competition shapes the landscape of X-chromosome-linked genetic diversity.

01-08-2024

PloS one

Head-to-head comparison of composite and individual biomarkers to predict clinical benefit to PD-1 blockade in non-small cell lung cancer.

31-07-2024

Nature reviews. Cancer

Rational combination of cancer therapies with PD1 axis blockade.

30-07-2024

Nature protocols

Quantifying genome-wide transcription factor binding affinities for chromatin using BANC-seq.

30-07-2024

Nature communications

The small CRL4^CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics.

29-07-2024

bioRxiv : the preprint server for biology

Optimized reporters for multiplexed detection of transcription factor activity.

26-07-2024

Cancers

Adverse Events in Anti-PD-1-Treated Adjuvant and First-Line Advanced Melanoma Patients.

26-07-2024

PloS one

Head and Neck Paraganglioma (HNPGL) Registry: A study protocol for prospective data collection in patients with Head and Neck Paragangliomas.

26-07-2024

BMC cancer

Pembrolizumab plus either epacadostat or placebo for cisplatin-ineligible urothelial carcinoma: results from the ECHO-307/KEYNOTE-672 study.

25-07-2024

Journal of cancer survivorship : research and practice

Prevalence and determinants of sleep problems in cancer survivors compared to a normative population: a PROFILES registry study.

24-07-2024

Nature communications

Single gene analysis in yeast suggests nonequilibrium regulatory dynamics for transcription.

23-07-2024

Current biology : CB

Cell biology: Converging paths to cohesion.

22-07-2024

Journal of medical genetics

Validation of the BOADICEA model in a prospective cohort of BRCA1/2 pathogenic variant carriers.

19-07-2024

iScience

"Radical" differences between two FLIM microscopes affect interpretation of cell signaling dynamics.

19-07-2024

Practical radiation oncology

Target Volume Optimization for Localized Prostate Cancer.

18-07-2024

Journal of the National Cancer Institute

Risk factors for breast cancer subtypes by race and ethnicity: A scoping review.

17-07-2024

Journal of experimental & clinical cancer research : CR

Emerging frontiers in androgen receptor research for prostate Cancer: insights from the 2nd international androgen receptor Symposium.

17-07-2024

The regulatory grammar of human promoters uncovered by MPRA-trained deep learning

15-07-2024

Key

Nuclear medicine and biology

Transcatheter pseudo-vascular isolation for localization and concentration of a large molecule theranostic probe into a transgenic OncoPIG kidney tumor.

15-07-2024

BMC medical genomics

Co-expression in tissue-specific gene networks links genes in cancer-susceptibility loci to known somatic driver genes.

15-07-2024

European radiology

Diagnostic performance of ADC and ADCratio in MRI-based prostate cancer assessment: A systematic review and meta-analysis.

12-07-2024

Vaccines

Protection of K18-hACE2 Mice against SARS-CoV-2 Challenge by a Capsid Virus-like Particle-Based Vaccine.

12-07-2024

Oncogenesis

Gemcitabine as chemotherapy of head and neck cancer in Fanconi anemia patients.

11-07-2024

Journal of the National Comprehensive Cancer Network : JNCCN

Chemotherapy-Induced Peripheral Neuropathy in Patients With Gastroesophageal Cancer.

08-07-2024

Cell stem cell

Deciphering lineage specification during early embryogenesis in mouse gastruloids using multilayered proteomics.

05-07-2024

Nature communications

Multi-modal generative modeling for joint analysis of single-cell T cell receptor and gene expression data.

03-07-2024

Clinical pharmacokinetics

Evaluating the Clinical Impact and Feasibility of Therapeutic Drug Monitoring of Pazopanib in a Real-World Soft-Tissue Sarcoma Cohort.

01-07-2024

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Patient-reported outcomes after personalised dose-escalation for stage II-III non-small-cell lung cancer patients: Results from the randomised ARTFORCE PET-Boost trial.

01-07-2024

Clinical pharmacokinetics

Population Pharmacokinetics of Inotuzumab Ozogamicin in Pediatric Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia: Results of Study ITCC-059.

01-07-2024

Cancer discovery

Paradoxical Activation of Oncogenic Signaling as a Cancer Treatment Strategy.

01-07-2024

The Journal of pathology

Characterization of discordance between mismatch repair deficiency and microsatellite instability testing may prevent inappropriate treatment with immunotherapy.

01-07-2024

Cancer discovery

IL2 Targeted to CD8+ T Cells Promotes Robust Effector T-cell Responses and Potent Antitumor Immunity.

01-07-2024

Cancer chemotherapy and pharmacology

Impact of loperamide on the pharmacokinetics and tissue disposition of ritonavir-boosted oral docetaxel therapy; a preclinical assessment.

01-07-2024

Cancer discovery

CD8-Targeted IL2 Unleashes Tumor-Specific Immunity in Human Cancer Tissue by Reviving the Dysfunctional T-cell Pool.

01-07-2024

The Journal of pathology

Ductal carcinoma in situ develops within clonal fields of mutant cells in morphologically normal ducts.

01-07-2024

European journal of drug metabolism and pharmacokinetics

The Use of Microdosing for In vivo Phenotyping of Cytochrome P450 Enzymes: Where Do We Stand? A Narrative Review.

01-07-2024

Nature genetics

Understanding the genetic complexity of puberty timing across the allele frequency spectrum.

01-07-2024

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

A multicentric randomized controlled phase III trial of adaptive and 18F-FDG-PET-guided dose-redistribution in locally advanced head and neck squamous cell carcinoma (ARTFORCE).

01-07-2024

Nature

Human SARS-CoV-2 challenge uncovers local and systemic response dynamics.

01-07-2024

PNAS nexus

Dual role of proliferating cell nuclear antigen monoubiquitination in facilitating Fanconi anemia-mediated interstrand crosslink repair.

01-07-2024

Cancer

Employment outcomes of adolescent and young adult cancer survivors and their partners: A Dutch population-based study.

01-07-2024

Cancer treatment reviews

Agnostic drug development revisited.

01-07-2024

FEBS letters

Nuclear receptor Nur77 and Yin-Yang 1 synergistically increase mitochondrial abundance and activity in macrophages.

01-07-2024

The Journal of antimicrobial chemotherapy

Skin pharmacokinetics of miltefosine in the treatment of post-kala-azar dermal leishmaniasis in South Asia.

01-07-2024

Medical physics

Impact of cone-beam computed tomography artifacts on dose calculation accuracy for lung cancer.

01-07-2024

Journal for immunotherapy of cancer

Mapping the complexity and diversity of tertiary lymphoid structures in primary and peritoneal metastatic gastric cancer.

01-07-2024

Physics and imaging in radiation oncology

Validation of quantitative magnetic resonance imaging techniques in head and neck healthy structures involved in the salivary and swallowing function: Accuracy and repeatability.

01-07-2024

Cancer chemotherapy and pharmacology

Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data.

01-07-2024

Cancer discovery

CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma.

01-07-2024

Psychological medicine

The mediating role of health behaviors in the association between depression, anxiety and cancer incidence: an individual participant data meta-analysis.

01-07-2024