Publications

Trials

Design of a multinational randomized controlled trial to assess the effects of structured and individualized exercise in patients with metastatic breast cancer on fatigue and quality of life: the EFFECT study.

29-07-2022

Frontiers in neuroscience

Multi-Coil MRI Reconstruction Challenge-Assessing Brain MRI Reconstruction Models and Their Generalizability to Varying Coil Configurations.

26-07-2022

PloS one

Molecular characterization of gastric adenocarcinoma diagnosed in patients previously treated for Hodgkin lymphoma or testicular cancer.

26-07-2022

Methods in molecular biology (Clifton, N.J.)

Acute Protein Depletion Strategies to Functionally Dissect the 3D Genome.

23-07-2022

Nucleic acids research

Division of labor within the DNA damage tolerance system reveals non-epistatic and clinically actionable targets for precision cancer medicine.

22-07-2022

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Prognostic Value of Stromal Tumor-Infiltrating Lymphocytes in Young, Node-Negative, Triple-Negative Breast Cancer Patients Who Did Not Receive (neo)Adjuvant Systemic Therapy.

20-07-2022

Scientific reports

High expression of secretory leukocyte protease inhibitor (SLPI) in stage III micro-satellite stable colorectal cancer is associated with reduced disease recurrence.

16-07-2022

Cancer

Psychosocial consequences of surviving cancer diagnosed and treated in childhood versus in adolescence/young adulthood: A call for clearer delineation between groups.

15-07-2022

Science translational medicine

NK cells with tissue-resident traits shape response to immunotherapy by inducing adaptive antitumor immunity.

13-07-2022

Pharmaceuticals (Basel, Switzerland)

Predictiveness of the Human-CYP3A4-Transgenic Mouse Model (Cyp3aXAV) for Human Drug Exposure of CYP3A4-Metabolized Drugs.

13-07-2022

Cancers

Uncovering the Contribution of Moderate-Penetrance Susceptibility Genes to Breast Cancer by Whole-Exome Sequencing and Targeted Enrichment Sequencing of Candidate Genes in Women of European Ancestry.

11-07-2022

Diagnostics (Basel, Switzerland)

Exploiting the Dixon Method for a Robust Breast and Fibro-Glandular Tissue Segmentation in Breast MRI.

11-07-2022

Research involvement and engagement

A qualitative study on the involvement of adolescents and young adults (AYAs) with cancer during multiple research phases: "plan, structure, and discuss".

08-07-2022

Molecular cell

Systematic analysis of intrinsic enhancer-promoter compatibility in the mouse genome.

07-07-2022

Cancer discovery

Can Drug Repurposing Accelerate Precision Oncology?

06-07-2022

Genes

Tooth Formation as Experimental Model to Study Chemotherapy on Tissue Development: Effect of a Specific Dose of Temozolomide/Veliparib.

04-07-2022

Frontiers in medicine

A Comparison of Post-marketing Measures Imposed by Regulatory Agencies to Confirm the Tissue-Agnostic Approach.

02-07-2022

PloS one

The impact of monosomies, trisomies and segmental aneuploidies on chromosomal stability.

02-07-2022

Cancers

Prediction Models and Decision Aids for Women with Ductal Carcinoma In Situ: A Systematic Literature Review.

02-07-2022

Critical reviews in oncology/hematology

Single agent Talimogene Laherparepvec for stage IIIB-IVM1c melanoma patients: A systematic review and meta-analysis.

01-07-2022

BJU international

Clinicopathological predictors of finding additional inguinal lymph node metastases in penile cancer patients after positive dynamic sentinel node biopsy: a European multicentre evaluation.

01-07-2022

Nature

Retrograde movements determine effective stem cell numbers in the intestine.

01-07-2022

Nature reviews. Clinical oncology

Integrated MRI-guided radiotherapy - opportunities and challenges.

01-07-2022

The Lancet. Oncology

Immunogenicity after second and third mRNA-1273 vaccination doses in patients receiving chemotherapy, immunotherapy, or both for solid tumours.

01-07-2022

Urologic oncology

Corrigendum to: Mechanistic target of rapamycin (mTOR) protein expression in the tumor and its microenvironment correlates with more aggressive pathology at cystectomy.

01-07-2022

Cancer chemotherapy and pharmacology

Efficacy and toxicity of vemurafenib and cobimetinib in relation to plasma concentrations, after administration via feeding tube in patients with BRAF-mutated thyroid cancer: a case series and review of literature.

01-07-2022

European radiology

Current controversies in TNM for the radiological staging of rectal cancer and how to deal with them: results of a global online survey and multidisciplinary expert consensus.

01-07-2022

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

Stability study of concentrate-solvent mixture & infusion solutions of Jevtana® cabazitaxel for extended multi-dosing.

01-07-2022

Critical reviews in oncology/hematology

Prognostic value of CT characteristics in GEP-NET: A systematic review.

01-07-2022

British journal of clinical pharmacology

Exposure-response relationship of ramucirumab in RANGE, a randomized phase III trial in advanced urothelial carcinoma refractory to platinum therapy.

01-07-2022

European journal of cancer (Oxford, England : 1990)

Clustering of EORTC QLQ-C30 health-related quality of life scales across several cancer types: Validation study.

01-07-2022

Clinical nuclear medicine

18F-FDG PET/CT During Neoadjuvant Targeted Therapy in Prior Unresectable Stage III Melanoma Patients: Can (Early) Metabolic Imaging Predict Histopathologic Response or Recurrence?

01-07-2022

Familial cancer

Positive experiences of healthcare professionals with a mainstreaming approach of germline genetic testing for women with ovarian cancer.

01-07-2022

BJU international

Cytoreductive nephrectomy and exposure to sunitinib - a post hoc analysis of the Immediate Surgery or Surgery After Sunitinib Malate in Treating Patients With Metastatic Kidney Cancer (SURTIME) trial.

01-07-2022

Journal of palliative care

Shared Perspectives of Patients With Advanced Cancer and Their Informal Caregivers on Essential Aspects of Health Care: A Qualitative Study.

01-07-2022

Breast cancer research and treatment

Survival of BRCA1/BRCA2-associated pT1 breast cancer patients, a cohort study.

01-07-2022

The Journal of pathology

Beyond the snapshot: optimizing prognostication and prediction by moving from fixed to functional multidimensional cancer pathology.

01-07-2022

European urology focus

Overall Survival of Patients Receiving Cisplatin or Carboplatin for Primary Metastatic Urothelial Carcinoma of the Bladder: A Contemporary Dutch Nationwide Cohort Study.

01-07-2022

Nature immunology

Author Correction: Replicative history marks transcriptional and functional disparity in the CD8⁺ T cell memory pool.

01-07-2022

Medical image analysis

DeepSMILE: Contrastive self-supervised pre-training benefits MSI and HRD classification directly from H&E whole-slide images in colorectal and breast cancer.

01-07-2022

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Image-based analysis of skeletal muscle mass predicts cisplatin dose-limiting toxicity in patients with locally advanced head and neck cancer.

01-07-2022

Cancer chemotherapy and pharmacology

Development of a population pharmacokinetic/pharmacodynamic model for various oral paclitaxel formulations co-administered with ritonavir and thrombospondin-1 based on data from early phase clinical studies.

01-07-2022

Breast cancer research and treatment

Limiting systemic endocrine overtreatment in postmenopausal breast cancer patients with an ultralow classification of the 70-gene signature.

01-07-2022

British journal of cancer

Low probability of disease cure in advanced ovarian carcinomas before the PARP inhibitor era.

01-07-2022

Journal for immunotherapy of cancer

Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma.

01-07-2022

Journal for immunotherapy of cancer

Dendritic cell-mediated cross presentation of tumor-derived peptides is biased against plasma membrane proteins.

01-07-2022

Clinical pharmacology and therapeutics

Dihydropyrimidine Dehydrogenase Phenotyping Using Pretreatment Uracil: A Note of Caution Based on a Large Prospective Clinical Study.

01-07-2022

Epidemiology (Cambridge, Mass.)

A Multipollutant Approach to Estimating Causal Effects of Air Pollution Mixtures on Overall Mortality in a Large, Prospective Cohort.

01-07-2022

Clinical breast cancer

The Effects of Being Informed About Chemotherapy-Related Cognitive Symptoms With And Without Self-Affirmation on Perceived Cognitive Symptoms of Breast Cancer Patients: A Randomized Prospective, Longitudinal Study.

01-07-2022

Physics and imaging in radiation oncology

Strategies for tackling the class imbalance problem of oropharyngeal primary tumor segmentation on magnetic resonance imaging.

01-07-2022