Publications

Frontiers in oncology

Loss of telomere protection: consequences and opportunities.

19-04-2013

Clinical cancer research : an official journal of the American Association for Cancer Research

Abcc4 together with abcb1 and abcg2 form a robust cooperative drug efflux system that restricts the brain entry of camptothecin analogues.

15-04-2013

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Quantification of cabazitaxel, its metabolite docetaxel and the determination of the demethylated metabolites RPR112698 and RPR123142 as docetaxel equivalents in human plasma by liquid chromatography-tandem mass spectrometry.

15-04-2013

The Journal of cell biology

Systematic dissection of dynein regulators in mitosis.

15-04-2013

Nature

Diverse and heritable lineage imprinting of early haematopoietic progenitors.

11-04-2013

The Journal of experimental medicine

Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathway.

08-04-2013

Current opinion in immunology

Human cancer regression antigens.

01-04-2013

Endocrine-related cancer

Rising incidence, no change in survival and decreasing mortality from thyroid cancer in The Netherlands since 1989.

01-04-2013

Current opinion in genetics & development

Chromatin organization: form to function.

01-04-2013

Gynecologic oncology

The relationship of body mass index with quality of life among endometrial cancer survivors: a study from the population-based PROFILES registry.

01-04-2013

Molecular oncology

Mouse models for lung cancer.

01-04-2013

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Response to induction chemotherapy and surgery in non-organ confined bladder cancer: a single institution experience.

01-04-2013

Molecular oncology

Genetically engineered mouse models of PI3K signaling in breast cancer.

01-04-2013

The Netherlands journal of medicine

Recent advances towards the clinical application of DNA vaccines.

01-04-2013

Nature reviews. Molecular cell biology

Senescence: back to telomeres.

01-04-2013

Biomedical chromatography : BMC

Method development and validation for the quantification of dasatinib, erlotinib, gefitinib, imatinib, lapatinib, nilotinib, sorafenib and sunitinib in human plasma by liquid chromatography coupled with tandem mass spectrometry.

01-04-2013

International journal of radiation oncology, biology, physics

Simultaneous integrated boost-intensity modulated radiation therapy with concomitant capecitabine and mitomycin C for locally advanced anal carcinoma: a phase 1 study.

01-04-2013

Investigational new drugs

Eribulin mesylate pharmacokinetics in patients with solid tumors receiving repeated oral ketoconazole.

01-04-2013

Therapeutic drug monitoring

Quantification of sunitinib and N-desethyl sunitinib in human EDTA plasma by liquid chromatography coupled with electrospray ionization tandem mass spectrometry: validation and application in routine therapeutic drug monitoring.

01-04-2013

Nature reviews. Nephrology

Cell-matrix adhesion of podocytes in physiology and disease.

01-04-2013

Nature reviews. Molecular cell biology

Senescence: back to telomeres.

01-04-2013

Cell

Single-cell dynamics of genome-nuclear lamina interactions.

28-03-2013

Proceedings of the National Academy of Sciences of the United States of America

Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis.

26-03-2013

The Journal of biological chemistry

Cathepsin-mediated necrosis controls the adaptive immune response by Th2 (T helper type 2)-associated adjuvants.

15-03-2013

International journal of radiation oncology, biology, physics

Targeted radiosensitization by the Chk1 inhibitor SAR-020106.

15-03-2013

Blood

Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function.

14-03-2013

Cancer nursing

The Cancer Worry Scale: detecting fear of recurrence in breast cancer survivors.

02-03-2013

The Journal of pathology

An α-E-catenin (CTNNA1) mutation in hereditary diffuse gastric cancer.

01-03-2013

Journal of radiation oncology

Volume changes in soft tissue sarcomas during preoperative radiotherapy of extremities evaluated using cone-beam CT.

01-03-2013

Journal of palliative medicine

Information provision and patient reported outcomes in patients with metastasized colorectal cancer: results from the PROFILES registry.

01-03-2013

Biochimica et biophysica acta

Anticancer mechanisms and clinical application of alkylphospholipids.

01-03-2013

Annals of oncology : official journal of the European Society for Medical Oncology

Early development of the metabolic syndrome after chemotherapy for testicular cancer.

01-03-2013

Analytical and bioanalytical chemistry

Pharmacodynamic assay of thymidylate synthase activity in peripheral blood mononuclear cells.

01-03-2013

Haematologica

A high level of fatigue among long-term survivors of non-Hodgkin's lymphoma: results from the longitudinal population-based PROFILES registry in the south of the Netherlands.

01-03-2013

Psycho-oncology

Illness perceptions in cancer survivors: what is the role of information provision?

01-03-2013

Analytical and bioanalytical chemistry

Correction of peripheral blood mononuclear cell cytosolic protein for hemoglobin contamination.

01-03-2013

Drugs in R&D

Pharmacokinetics and excretion of 14C-bendamustine in patients with relapsed or refractory malignancy.

01-03-2013

The Journal of biological chemistry

Ubiquitination by the membrane-associated RING-CH-8 (MARCH-8) ligase controls steady-state cell surface expression of tumor necrosis factor-related apoptosis inducing ligand (TRAIL) receptor 1.

01-03-2013

Cancer immunology, immunotherapy : CII

Mimicking homeostatic proliferation in vitro generates T cells with high anti-tumor function in non-lymphopenic hosts.

01-03-2013

BMC cancer

Adaptive and innovative Radiation Treatment FOR improving Cancer treatment outcomE (ARTFORCE); a randomized controlled phase II trial for individualized treatment of head and neck cancer.

22-02-2013

Molecular cell

A network model of the molecular organization of chromatin in Drosophila.

21-02-2013

Journal of medical Internet research

A systematic review of web-based interventions for patient empowerment and physical activity in chronic diseases: relevance for cancer survivors.

20-02-2013

Clinical cancer research : an official journal of the American Association for Cancer Research

Influence of human OATP1B1, OATP1B3, and OATP1A2 on the pharmacokinetics of methotrexate and paclitaxel in humanized transgenic mice.

15-02-2013

Mol Cell Proteomics: Molecular & cellular proteomics: MCP

Proteomics of genetically engineered mouse mammary tumors identifies fatty acid metabolism members as potential predictive markers for cisplatin resistance

08-02-2013

Molecular cell

eRNAs are required for p53-dependent enhancer activity and gene transcription.

07-02-2013

PLoS genetics

Dot1-dependent histone H3K79 methylation promotes activation of the Mek1 meiotic checkpoint effector kinase by regulating the Hop1 adaptor.

06-02-2013

British journal of clinical pharmacology

Pharmacokinetics of eribulin mesylate in patients with solid tumours receiving repeated oral rifampicin.

01-02-2013

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Quality of life of older rectal cancer patients is not impaired by a permanent stoma.

01-02-2013

Acta oncologica (Stockholm, Sweden)

Development of a disease-specific health-related quality of life questionnaire (THYCA-QoL) for thyroid cancer survivors.

01-02-2013

Acta oncologica (Stockholm, Sweden)

Health-related quality of life and disease specific symptoms in long-term thyroid cancer survivors: a study from the population-based PROFILES registry.

01-02-2013