Krista Joosten

After a PhD in theory of quantum properties in laser physics, I opted for research with a more direct link to socially relevant applications and specifically cancer research.  In the group of Anastassis Perrakis I use computer programming and modeling to improve building 3D protein models and study how to validate the quality of these models. We presently focus on combining experimental data, namely the three dimensional electron density maps that are computed from X-ray diffraction experiments of macromolecular crystals, knowledge from chemistry, and the statistical properties derived from existing models, to provide better structural models to scientists worldwide.