Number of immune cells predicts necessity of chemotherapy in triple negative breast cancer


One in five young women with triple-negative breast cancer (an aggressive form of breast cancer) and clean lymph nodes faces a favorable prognosis, even without chemotherapy treatment. The risk of metastases and, as a result, the need for chemotherapy can be predicted by looking at the amount of immune cells (TIL) surrounding the tumor. This has been discovered by physician-scientist Vincent de Jong and others from physician and research leader Sabine Linn’s research group at the Netherlands Cancer Institute, in collaboration with UMC Utrecht, IKNL, and the International Working Group on TILS.

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