How one DNA mutation in breast cancer hijacks the immune system


One defective gene in breast tumour cells can promote metastases elsewhere in the body by steering the immune system in an undesirable direction. This is the p53 gene, which is deleted or mutated in the tumour cells of nearly 40% of breast cancer patients.

A paper about this discovery by the research group of immunologist and tumour biologist Karin de Visser of the Netherlands Cancer Institute was published in Nature on July 31

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