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DNA shield reveals itself


Not all patients with cancer respond equally well to drug therapies. This insensitivity is a multi-faceted beast. Researchers at the Netherlands Cancer Institute are trying to untangle why therapies sometimes do not work (anymore). Jacqueline Jacobs delves into the world of a molecular “shield” that protects DNA as it breaks. A search in which complexes are more complex than we thought, and one to which she added a new chapter last week.

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