“I'm from a small village in China. My parents were farmers, and I was the first in the family to attend university. I was also the first to go to Europe. I had several options and ended up deciding on Amsterdam, where I conducted research on proteins called carboxylesterase 1 (Ces1/CES1). These enzymes are involved in various processes in our bodies: they break down toxins like pesticides and metabolize medications as well. The level of activity of this enzyme varies among patients. Using mouse models, we investigated the functions of this enzyme and explored the factors that could explain the differences between individuals. It wasn't always easy; many of the experiments were relatively new, and it took some time to master the techniques. I've had engaging discussions about this challenging yet fascinating research with my mentors. I also have fond memories of all my colleagues in the lab. My English wasn't great when I first started, but everyone was so kind to me! I even came to greatly appreciate the Dutch direct way of communication.”
Changpei Gan will defend his thesis on November 13.
prof. dr. J.H. (Jos) Beijnen
A.H. (Alfred) Schinkel