Master’s degree (MSc) in Biology/Biochemistry (cum laude): June 1983, University of Amsterdam. Qualification to teach senior secondary pupils / high-school students in botany and zoology.
Ph.D. (cum laude): University of Amsterdam, January 11, 1989 on the thesis entitled: "Mitochondrial RNA polymerase of yeast" under the supervision of Prof. Dr. H.F. Tabak.
2007 - date
Tenured staff member, project leader “C”, The Netherlands Cancer Institute (equivalent to “full professor”).
2002 - 2007
Tenured staff member, project leader “B”, The Netherlands Cancer Institute (equivalent to “associate professor”).
1996 - 2002
Staff member (AvL fellow), The Netherlands Cancer Institute (equivalent to “assistant professor”).
1996 - 1997
Visiting Research Scientist, Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA. Sponsor: Michael M. Gottesman, M.D., Chief.
1988 - 1996
Postdoctoral investigator at the Netherlands Cancer Institute. Subject: Multidrug resistance and P-glycoproteins. Research group leader: Prof. Dr. P. Borst.
1983 - 1988
Ph.D. thesis research on structure and function of the mitochondrial RNA polymerase of Saccharomyces cerevisiae, carried out under the supervision of Prof. Dr. H.F. Tabak, University of Amsterdam.
2018 - date
Division Head, Division of Pharmacology, The Netherlands Cancer Institute.
2004 - 2008
Division Head, Division of Experimental Therapy, The Netherlands Cancer Institute.
2004 - 2007
Secretary of NKI Research Council.
2002 - 2007
Chairman internal NKI Animal User’s Committee.
Lectures and tutorials as part of the NKI Course on Experimental Oncology.
Supervision of graduate and undergraduate students.
Named 2014 Thomson Reuters “Highly Cited Researcher” in the area of Pharmacology and Toxicology: belonging to the 1% most highly cited researchers in this research area (2002-2012). Website: www.highlycited.com
Antoni van Leeuwenhoek Prize 1994 for research on the biological role of P-glycoproteins involved in multidrug resistance.
Dutch Galenus Prize 1993 for work on P-glycoprotein and its role in the blood-brain barrier.