search

menu

  • Research Research
    • Where science meets inspired minds

    • Back
    • Research
    • Our Science
    • Research Groups
    • Facilities & Platforms
    • Clinical research
    • Find a researcher
    • Publications
    • Knowledge Transfer
  • Careers & study Careers & study
    • Become a leader in cancer research

    • Back
    • Careers & study
    • Vacancies
    • Faculty
    • Scientific staff
    • Scientific support staff
    • Postdoctoral fellows
    • PhD Students
    • Operational staff
    • Clinical fellows
    • Life in Amsterdam
    • Student internships
  • News & Events News & Events
    • Check out our stories and events

    • Back
    • News & Events
    • News
    • Media & Press
    • Calendar
  • About us About us
    • Maximum impact for cancer patients

    • Back
    • About us
    • Our vision
    • Organization
    • Collaborations
    • Responsible Research
    • Support us
    • Visit us
    • Contact us
  • Support us
Support us
  • Home
  • News
  • News & Events
  • News
  • PhD Defence Ewald van Dyk: Detecting cancer genes by counting DNA copies

PhD Defence Ewald van Dyk: Detecting cancer genes by counting DNA copies

09-01-2019

There are two main genetic mechanisms that can activate or suppress cancer genes: DNA mutations and alterations in the DNA copy number. Ewald van Dyk, who will defend his PhD thesis on Wednesday, January 9th, at Delft University of Technology, focused on the latter.

He designed a statistical framework, based on copy number profiles, for finding peak regions on the genome that are likely to harbor both oncogenes and tumor suppressors for any given cancer type. Ewald van Dyk: 'If we consider only DNA copy number alterations, ignoring all other sources such as mutation data, we can already detect hundreds of such regions. One cannot help but wonder just how many genes are causally linked to cancer.'

Ewald van Dyk conducted his PhD research in the Lodewyk Wessel lab and is currently working as a postdoc in the Karin de Visser lab, unraveling mechanisms by which tumors affect the immune system.

When: Wednesday January 9th, 12.30 AM
Where: Delft Technical University
Thesis: Computational Analysis of Copy Number profiles of tumors
Supervisors: Lodewyk Wessels (NKI) and Marcel Reinders (Delft Technical University)

 

PhD Defence Ewald van Dyk: Detecting cancer genes by counting DNA copies

When: Wednesday January 9th, 11.30 AM

Where: Erasmus MC

Thesis title: Functional Identification of Regulatory Elements in the Human Genome

 

Other tumors

Support our science?

Learn more

Where science meets inspired minds

Contact

Plesmanlaan 121
1066CX Amsterdam

020 512 9111 communicatie@nki.nl

Quick links

  • Vacancies
  • News
  • Contact us
  • Media & Press

Follow us on

Disclaimer
Privacy statement
Cookies
Change cookie settings

This site uses cookies

This website uses cookies to ensure you get the best experience on our website.