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09Jul 2020

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Cancer Core Europe centres develop web-based decision-making support tool for oncologists to improve treatment selection

In Nature Medicine, clinical researchers from the Cancer Core Europe (CCE) Comprehensive Cancer Cemtres describe a new precision cancer medicine technology to inform the use of individualised treatments in clinical trials, guided by the genomics profile of the tumours.

The portal has been developed at Karolinska Institutet and SciLifeLab together with clinical researchers from seven European comprehensive cancer centres who are part of the Cancer Core Europe Consortium, and has currently analysed more than 500 patients' samples.

Emile Voest, who is president of Cancer Core Europe, calls this new decision aid 'an beautiful example of how international collaboration improves the quality of patient care.

NKI internist-clinical pharmacologist Frans Opdam relates how those CCE clinicians working together in the tumour-agnostic Basket of Baskets trial use this new genomics-based decision aid tool in their weekly multidisciplinary meetings. 'Each Wednesday, we discuss the clinical relevance of the outcomes of our patients' tumor genetic analyses to decide which patients are electable for this trial.'

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