Our Resources
Over the years, we have collected several tumor sample sets from specific bladder cancer patient cohorts for our translational research. These include:
- Paired samples pre- and post-therapy for patients who received neoadjuvant chemotherapy:
https://pubmed.ncbi.nlm.nih.gov/25636205/
https://pubmed.ncbi.nlm.nih.gov/30224344/
- A large cohort of untreated cystectomies:
https://pubmed.ncbi.nlm.nih.gov/32682615/
https://pubmed.ncbi.nlm.nih.gov/32616859/
The basis for our translational work in the bladder cancer tumor-immune microenvironment is RNA sequencing and multiplex immunofluorescence, as has been done in the NABUCCO trial:
https://pubmed.ncbi.nlm.nih.gov/33046870/
For several of our studies we have used functional genetic screens, using the screening facility led by Roderick Beijersbergen: