Risk of acute large cell lymphoma of the breast in women with breast implants

A topic related to late effects of cancer treatment concerns our research related to breast implants. In 2008 we reported the first epidemiological study demonstrating that breast implants are associated with a strongly increased risk of a rare type of breast lymphoma, i.e. anaplastic large-cell lymphoma (ALCL) (De Jong et al, JAMA 2008). We confirmed these results in a much larger nationwide study. While the relative risk associated with implants was high (RR>400), cumulative risks of breast-ALCL in women with implants are low, i.e. 82 per million at 70 years (de Boer et al, JAMA Oncol, 2018).

Recently, we showed that women with BRCA 1/2 mutations and implants have an increased risk to develop breast ALCL. (de Boer et al, Blood, 2020)

This site uses cookies

This website uses cookies to ensure you get the best experience on our website.