Click on the links for relevant publications, protocols and other resources.
- DamID and pA-DamID: methods for the mapping of in vivo protein-genome interactions
- m6A-tracer: a derivative of DamID, to visualize DNA that has contacted a protein of interest in living cells
- TRIP: a method to measure the impact of chromatin on gene regulation at thousands of genomic locations in parallel
- TIDE and TIDER: simple, cheap and quantitative methods to measure genome editing efficiency by CRISPR/Cas9
- SuRE: a massively parallel reporter assay to map and measure the activity of regulatory elements in entire mammalian genomes
- A tool to separate genomic loci (such as enhancers and promoters) spatially inside the cell nucleus
- A variant of SuRE to test the functionality of thousands of enhancer/promoter pairs
- A variant of TRIP to test the impact of chromatin context on DNA repair
- A screen to find proteins that control gene regulation inside LADs
Most of our important plasmids can be obtained from Addgene. For other plasmids please contact us.
Our datasets and code are available from various repositories:
• 4D Nucleome: DamID-seq and pA-DamID-seq maps of nuclear lamina interactions
• GEO: A variety of whole-genome datasets (DamID, mRNA-seq, TRIP, ...)
• OSF: Various types of data (some unpublished), records of lab notebooks
• Github: Code of various published and unpublished projects
Contact us if you are interested!