Publications

Drug discovery today

Impact of organ-on-a-chip technology on pharmaceutical R&D costs.

01-09-2019

Medical physics

Two-dimensional EPID dosimetry for an MR-linac: Proof of concept.

01-09-2019

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Micro cone beam computed tomography for sensitive assessment of radiation-induced late lung toxicity in preclinical models.

01-09-2019

Acta psychiatrica Scandinavica

Phenotypic factors associated with amisulpride-induced weight gain in first-episode psychosis patients (from the OPTiMiSE cohort).

01-09-2019

Journal of mammary gland biology and neoplasia

GATA3 Truncating Mutations Promote Cistromic Re-Programming In Vitro, but Not Mammary Tumor Formation in Mice.

01-09-2019

Health informatics journal

A global, incremental development method for a web-based prostate cancer treatment decision aid and usability testing in a Dutch clinical setting.

01-09-2019

Journal of biophotonics

Optical coherence tomography to detect acute esophageal radiation-induced damage in mice: A validation study.

01-09-2019

Journal of geriatric oncology

The impact of colorectal surgery on health-related quality of life in older functionally dependent patients with cancer - A longitudinal follow-up study.

01-09-2019

Cancer causes & control : CCC

Clinical characteristics and survival patterns of subsequent sarcoma, breast cancer, and melanoma after childhood cancer in the DCOG-LATER cohort.

01-09-2019

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Evaluating a professional patient navigation intervention in a supportive care setting.

01-09-2019

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Long-term survival after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with peritoneal metastases of urachal cancer.

01-09-2019

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of an LC-MS/MS method with a broad linear dynamic range for the quantification of tivozanib in human and mouse plasma, mouse tissue homogenates, and culture medium.

01-09-2019

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Assessment of Simplified Methods for Quantification of ¹⁸F-FDHT Uptake in Patients with Metastatic Castration-Resistant Prostate Cancer.

01-09-2019

Molecular cancer therapeutics

In Vivo ERK1/2 Reporter Predictively Models Response and Resistance to Combined BRAF and MEK Inhibitors in Melanoma.

01-09-2019

Journal of psychosomatic research

Effects and moderators of exercise on sleep in adults with cancer: Individual patient data and aggregated meta-analyses.

01-09-2019

European journal of cancer (Oxford, England : 1990)

Safety and efficacy of nivolumab in patients with rare melanoma subtypes who progressed on or after ipilimumab treatment: a single-arm, open-label, phase II study (CheckMate 172).

01-09-2019

Scientific reports

Two truncating variants in FANCC and breast cancer risk.

29-08-2019

Nature communications

Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin.

23-08-2019

The Journal of biological chemistry

The domain architecture of the protozoan protein J-DNA-binding protein 1 suggests synergy between base J DNA binding and thymidine hydroxylase activity.

23-08-2019

Nucleic acids research

DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy.

22-08-2019

ESMO open

Susceptible loci associated with autoimmune disease as potential biomarkers for checkpoint inhibitor-induced immune-related adverse events.

20-08-2019

ESMO open

Targeting prognostic proinflammatory biomarkers to improve outcome on IO drugs.

20-08-2019

BMC medical informatics and decision making

The impact of an online patient decision aid for women with breast cancer considering immediate breast reconstruction: study protocol of a multicenter randomized controlled trial.

19-08-2019

The international journal of behavioral nutrition and physical activity

Which cancer survivors are at risk for a physically inactive and sedentary lifestyle? Results from pooled accelerometer data of 1447 cancer survivors.

16-08-2019

BMC gastroenterology

Prognostic value of microvessel density in stage II and III colon cancer patients: a retrospective cohort study.

16-08-2019

The New England journal of medicine

Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma.

15-08-2019

Clinical cancer research : an official journal of the American Association for Cancer Research

Divergent Biological Response to Neoadjuvant Chemotherapy in Muscle-invasive Bladder Cancer.

15-08-2019

Clinical cancer research : an official journal of the American Association for Cancer Research

Prognostic Value of Residual Disease after Neoadjuvant Therapy in HER2-Positive Breast Cancer Evaluated by Residual Cancer Burden, Neoadjuvant Response Index, and Neo-Bioscore.

15-08-2019

Key Publication

ACS combinatorial science

High-Affinity α₅β₁-Integrin-Selective Bicyclic RGD Peptides Identified via Screening of Designed Random Libraries.

12-08-2019

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Cost Effectiveness of Interval Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy in Stage III Ovarian Cancer on the Basis of a Randomized Phase III Trial.

10-08-2019

Cell

The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase.

08-08-2019

Breast cancer research : BCR

Cancer-immune interactions in ER-positive breast cancers: PI3K pathway alterations and tumor-infiltrating lymphocytes.

07-08-2019

Lung cancer (Amsterdam, Netherlands)

Variation in the time to treatment for stage III and IV non-small cell lung cancer patients for hospitals in the Netherlands.

01-08-2019

Expert review of medical devices

Recent advances in nuclear and hybrid detection modalities for image-guided surgery.

01-08-2019

British journal of cancer

Ductal carcinoma in situ: to treat or not to treat, that is the question.

01-08-2019

Key Publication

European radiology

Quantitative 3-T multi-parametric MRI and step-section pathology of recurrent prostate cancer patients after radiation therapy.

01-08-2019

Annals of surgery

Prognostic Impact of Breast-Conserving Therapy Versus Mastectomy of BRCA1/2 Mutation Carriers Compared With Noncarriers in a Consecutive Series of Young Breast Cancer Patients.

01-08-2019

Nature

Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis.

01-08-2019

Key Publication

Pediatric blood & cancer

The involvement of primary care physicians in care for childhood cancer survivors.

01-08-2019

Breast (Edinburgh, Scotland)

Utility of diagnostic breast excision biopsies during two decades of screening mammography.

01-08-2019

Journal of neuroendocrinology

Identification of mineralocorticoid receptor target genes in the mouse hippocampus.

01-08-2019

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

Sensorineural Hearing Loss After Adoptive Cell Immunotherapy for Melanoma Using MART-1 Specific T Cells: A Case Report and Its Pathophysiology.

01-08-2019

Analytical and bioanalytical chemistry

Development and validation of a bioanalytical method for the quantification of the CDK4/6 inhibitors abemaciclib, palbociclib, and ribociclib in human and mouse matrices using liquid chromatography-tandem mass spectrometry.

01-08-2019

Pharmacological research

Brain accumulation of osimertinib and its active metabolite AZ5104 is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein).

01-08-2019

Breast cancer research and treatment

Intra-arterial Mitomycin C infusion in a large cohort of advanced liver metastatic breast cancer patients: safety, efficacy and factors influencing survival.

01-08-2019

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Relevance of Endoxifen Concentrations: Absence of Evidence Is Not Evidence of Absence.

01-08-2019

JACC. Cardiovascular imaging

State-of-the-Art Deep Learning in Cardiovascular Image Analysis.

01-08-2019

Current opinion in chemical biology

Visualizing transcription: key to understanding gene expression dynamics.

01-08-2019

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Organ Function Preservation Failure after (Chemo)Radiotherapy in Head and Neck Cancer: A Retrospective Cohort Analysis.

01-08-2019

European journal of nuclear medicine and molecular imaging

Lesion detection by [⁸⁹Zr]Zr-DFO-girentuximab and [¹⁸F]FDG-PET/CT in patients with newly diagnosed metastatic renal cell carcinoma.

01-08-2019

Impact of organ-on-a-chip technology on pharmaceutical R&D costs.

Two-dimensional EPID dosimetry for an MR-linac: Proof of concept.

Micro cone beam computed tomography for sensitive assessment of radiation-induced late lung toxicity in preclinical models.

Phenotypic factors associated with amisulpride-induced weight gain in first-episode psychosis patients (from the OPTiMiSE cohort).

GATA3 Truncating Mutations Promote Cistromic Re-Programming In Vitro, but Not Mammary Tumor Formation in Mice.

A global, incremental development method for a web-based prostate cancer treatment decision aid and usability testing in a Dutch clinical setting.

Optical coherence tomography to detect acute esophageal radiation-induced damage in mice: A validation study.

The impact of colorectal surgery on health-related quality of life in older functionally dependent patients with cancer - A longitudinal follow-up study.

Clinical characteristics and survival patterns of subsequent sarcoma, breast cancer, and melanoma after childhood cancer in the DCOG-LATER cohort.

Evaluating a professional patient navigation intervention in a supportive care setting.

Long-term survival after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with peritoneal metastases of urachal cancer.

Development and validation of an LC-MS/MS method with a broad linear dynamic range for the quantification of tivozanib in human and mouse plasma, mouse tissue homogenates, and culture medium.

Assessment of Simplified Methods for Quantification of 18F-FDHT Uptake in Patients with Metastatic Castration-Resistant Prostate Cancer.

In Vivo ERK1/2 Reporter Predictively Models Response and Resistance to Combined BRAF and MEK Inhibitors in Melanoma.

Effects and moderators of exercise on sleep in adults with cancer: Individual patient data and aggregated meta-analyses.

Safety and efficacy of nivolumab in patients with rare melanoma subtypes who progressed on or after ipilimumab treatment: a single-arm, open-label, phase II study (CheckMate 172).

Two truncating variants in FANCC and breast cancer risk.

Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin.

The domain architecture of the protozoan protein J-DNA-binding protein 1 suggests synergy between base J DNA binding and thymidine hydroxylase activity.

DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy.

Susceptible loci associated with autoimmune disease as potential biomarkers for checkpoint inhibitor-induced immune-related adverse events.

Targeting prognostic proinflammatory biomarkers to improve outcome on IO drugs.

The impact of an online patient decision aid for women with breast cancer considering immediate breast reconstruction: study protocol of a multicenter randomized controlled trial.

Which cancer survivors are at risk for a physically inactive and sedentary lifestyle? Results from pooled accelerometer data of 1447 cancer survivors.

Prognostic value of microvessel density in stage II and III colon cancer patients: a retrospective cohort study.

Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma.

Divergent Biological Response to Neoadjuvant Chemotherapy in Muscle-invasive Bladder Cancer.

Prognostic Value of Residual Disease after Neoadjuvant Therapy in HER2-Positive Breast Cancer Evaluated by Residual Cancer Burden, Neoadjuvant Response Index, and Neo-Bioscore.

High-Affinity α5β1-Integrin-Selective Bicyclic RGD Peptides Identified via Screening of Designed Random Libraries.

Cost Effectiveness of Interval Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy in Stage III Ovarian Cancer on the Basis of a Randomized Phase III Trial.

The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase.

Cancer-immune interactions in ER-positive breast cancers: PI3K pathway alterations and tumor-infiltrating lymphocytes.

Variation in the time to treatment for stage III and IV non-small cell lung cancer patients for hospitals in the Netherlands.

Recent advances in nuclear and hybrid detection modalities for image-guided surgery.

Ductal carcinoma in situ: to treat or not to treat, that is the question.

Quantitative 3-T multi-parametric MRI and step-section pathology of recurrent prostate cancer patients after radiation therapy.

Prognostic Impact of Breast-Conserving Therapy Versus Mastectomy of BRCA1/2 Mutation Carriers Compared With Noncarriers in a Consecutive Series of Young Breast Cancer Patients.

Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis.

The involvement of primary care physicians in care for childhood cancer survivors.

Utility of diagnostic breast excision biopsies during two decades of screening mammography.

Identification of mineralocorticoid receptor target genes in the mouse hippocampus.

Sensorineural Hearing Loss After Adoptive Cell Immunotherapy for Melanoma Using MART-1 Specific T Cells: A Case Report and Its Pathophysiology.

Development and validation of a bioanalytical method for the quantification of the CDK4/6 inhibitors abemaciclib, palbociclib, and ribociclib in human and mouse matrices using liquid chromatography-tandem mass spectrometry.

Brain accumulation of osimertinib and its active metabolite AZ5104 is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein).

Intra-arterial Mitomycin C infusion in a large cohort of advanced liver metastatic breast cancer patients: safety, efficacy and factors influencing survival.

Relevance of Endoxifen Concentrations: Absence of Evidence Is Not Evidence of Absence.

State-of-the-Art Deep Learning in Cardiovascular Image Analysis.

Visualizing transcription: key to understanding gene expression dynamics.

Organ Function Preservation Failure after (Chemo)Radiotherapy in Head and Neck Cancer: A Retrospective Cohort Analysis.

Lesion detection by [89Zr]Zr-DFO-girentuximab and [18F]FDG-PET/CT in patients with newly diagnosed metastatic renal cell carcinoma.

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Assessment of Simplified Methods for Quantification of ¹⁸F-FDHT Uptake in Patients with Metastatic Castration-Resistant Prostate Cancer.

High-Affinity α₅β₁-Integrin-Selective Bicyclic RGD Peptides Identified via Screening of Designed Random Libraries.

Lesion detection by [⁸⁹Zr]Zr-DFO-girentuximab and [¹⁸F]FDG-PET/CT in patients with newly diagnosed metastatic renal cell carcinoma.