Publications

Breast cancer research and treatment

Survival after bilateral risk-reducing mastectomy in healthy BRCA1 and BRCA2 mutation carriers.

01-10-2019

Cancer letters

Low-dose triple drug combination targeting the PI3K/AKT/mTOR pathway and the MAPK pathway is an effective approach in ovarian clear cell carcinoma.

01-10-2019

British journal of clinical pharmacology

Nonlinear protein binding of phenytoin in clinical practice: Development and validation of a mechanistic prediction model.

01-10-2019

Molecular aspects of medicine

Circulating biomarkers for early detection and clinical management of colorectal cancer.

01-10-2019

Clinical cancer research : an official journal of the American Association for Cancer Research

The Promise of Neoadjuvant Immunotherapy and Surgery for Cancer Treatment.

01-10-2019

Clinical genitourinary cancer

Efficacy, Tolerance, and Plasma Levels of Abiraterone and Its Main Metabolites in a Patient With Metastatic Castration-resistant Prostate Cancer With a Hepatic Transplant.

01-10-2019

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Building a collaboration to improve surgical research through EORTC/ESSO 1409-CLIMB study: A prospective liver metastasis database with an integrated quality assurance program.

01-10-2019

Nature

The Drug Rediscovery protocol facilitates the expanded use of existing anticancer drugs.

01-10-2019

Key Publication

European urology

Single Lesion on Prostate-specific Membrane Antigen-ligand Positron Emission Tomography and Low Prostate-specific Antigen Are Prognostic Factors for a Favorable Biochemical Response to Prostate-specific Membrane Antigen-targeted Radioguided Surgery in Recurrent Prostate Cancer.

01-10-2019

Molecular aspects of medicine

The landscape of genomic copy number alterations in colorectal cancer and their consequences on gene expression levels and disease outcome.

01-10-2019

European urology

Surgical Safety of Cytoreductive Nephrectomy Following Sunitinib: Results from the Multicentre, Randomised Controlled Trial of Immediate Versus Deferred Nephrectomy (SURTIME).

01-10-2019

Journal of community genetics

Correction to: Clinicians' use of breast cancer risk assessment tools according to their perceived importance of breast cancer risk factors: an international survey.

01-10-2019

Physics and imaging in radiation oncology

Geometrical and dosimetric evaluation of breast target volume auto-contouring.

01-10-2019

Endocrine-related cancer

The molecular genetic make-up of male breast cancer.

01-10-2019

Cytometry. Part A : the journal of the International Society for Analytical Cytology

Multiparameter Flow Cytometry Assay for Quantification of Immune Cell Subsets, PD-1 Expression Levels and PD-1 Receptor Occupancy by Nivolumab and Pembrolizumab.

01-10-2019

Journal of physiotherapy

An international perspective on integrating physiotherapists in oncology care.

01-10-2019

Therapeutic drug monitoring

Simultaneous Quantification of Free Adalimumab and Infliximab in Human Plasma Using a Target-Based Sample Purification and Liquid Chromatography-Tandem Mass Spectrometry.

01-10-2019

European journal of immunology

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).

01-10-2019

Cell systems

A Comprehensive Network Atlas Reveals That Turing Patterns Are Common but Not Robust.

25-09-2019

Nature communications

Publisher Correction: Shared heritability and functional enrichment across six solid cancers.

23-09-2019

Nucleic acids research

Sharp kinking of a coiled-coil in MutS allows DNA binding and release.

19-09-2019

Clinical cancer research : an official journal of the American Association for Cancer Research

A Phase I Dose Escalation Study of Once-Weekly Oral Administration of Docetaxel as ModraDoc001 Capsule or ModraDoc006 Tablet in Combination with Ritonavir.

15-09-2019

Bioorganic & medicinal chemistry letters

A fragment-like approach to PYCR1 inhibition.

15-09-2019

Nature communications

Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma.

13-09-2019

Frontiers in immunology

Repertoire Sequencing of B Cells Elucidates the Role of UNG and Mismatch Repair Proteins in Somatic Hypermutation in Humans.

12-09-2019

Communications biology

Proteomic profiling of extracellular vesicles allows for human breast cancer subtyping.

12-09-2019

Pharmaceutical research

Metabolome Analysis Reveals Dermal Histamine Accumulation in Murine Dermatitis Provoked by Genetic Deletion of P-Glycoprotein and Breast Cancer Resistance Protein.

11-09-2019

BMC cancer

Study protocols of three parallel phase 1 trials combining radical radiotherapy with the PARP inhibitor olaparib.

10-09-2019

Journal of pharmaceutical and biomedical analysis

Development and validation of a liquid chromatography-tandem mass spectrometry assay for nine oral anticancer drugs in human plasma.

10-09-2019

Cell

The ChAHP Complex Counteracts Chromatin Looping at CTCF Sites that Emerged from SINE Expansions in Mouse.

05-09-2019

Journal of pharmaceutical and biomedical analysis

Liquid chromatography-tandem mass spectrometric assay for the quantification of galunisertib in human plasma and the application in a pre-clinical study.

05-09-2019

JAMA network open

Association of a Pathway-Specific Genetic Risk Score With Risk of Radiation-Associated Contralateral Breast Cancer.

04-09-2019

Key Publication

Molecular pharmaceutics

P-glycoprotein Limits Ribociclib Brain Exposure and CYP3A4 Restricts Its Oral Bioavailability.

03-09-2019

Psycho-oncology

Anxiety and depression mediate the association between chemotherapy-induced peripheral neuropathy and fatigue: Results from the population-based PROFILES registry.

01-09-2019

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Usability of an online application for reporting the burden of side effects in cancer patients.

01-09-2019

The Journal of surgical research

Feasibility of Micro-Computed Tomography Imaging for Direct Assessment of Surgical Resection Margins During Breast-Conserving Surgery.

01-09-2019

The Journal of molecular diagnostics : JMD

MammaPrint and BluePrint Molecular Diagnostics Using Targeted RNA Next-Generation Sequencing Technology.

01-09-2019

European journal of clinical pharmacology

Individualized dosing of oral targeted therapies in oncology is crucial in the era of precision medicine.

01-09-2019

Cancer chemotherapy and pharmacology

Cytochrome P450 3A4, 3A5, and 2C8 expression in breast, prostate, lung, endometrial, and ovarian tumors: relevance for resistance to taxanes.

01-09-2019

The Lancet. Oncology

Pembrolizumab versus ipilimumab in advanced melanoma (KEYNOTE-006): post-hoc 5-year results from an open-label, multicentre, randomised, controlled, phase 3 study.

01-09-2019

International journal of cancer

Assessment and management of bone health in women with early breast cancer receiving endocrine treatment in the DATA study.

01-09-2019

Clinical and translational radiation oncology

MRI basics for radiation oncologists.

01-09-2019

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

MRI-guided mid-position liver radiotherapy: Validation of image processing and registration steps.

01-09-2019

European urology focus

Defining the Tumor Microenvironment of Penile Cancer by Means of the Cancer Immunogram.

01-09-2019

Der Radiologe

[Imaging of rectal cancer. German version].

01-09-2019

Immuno-oncology technology

Getting visible with exciting IO tech!

01-09-2019

Oral oncology

Health-related quality of life of patients treated with chemoradiotherapy plus or minus prophylactic antibiotics to reduce the number of pneumonias for locally advanced head and neck cancer, the PANTAP study.

01-09-2019

International journal of radiation oncology, biology, physics

Multiparametric MRI Tumor Probability Model for the Detection of Locally Recurrent Prostate Cancer After Radiation Therapy: Pathologic Validation and Comparison With Manual Tumor Delineations.

01-09-2019

Biomedical optics express

Broadband hyperspectral imaging for breast tumor detection using spectral and spatial information.

01-09-2019

Drug discovery today

Impact of organ-on-a-chip technology on pharmaceutical R&D costs.

01-09-2019

Survival after bilateral risk-reducing mastectomy in healthy BRCA1 and BRCA2 mutation carriers.

Low-dose triple drug combination targeting the PI3K/AKT/mTOR pathway and the MAPK pathway is an effective approach in ovarian clear cell carcinoma.

Nonlinear protein binding of phenytoin in clinical practice: Development and validation of a mechanistic prediction model.

Circulating biomarkers for early detection and clinical management of colorectal cancer.

The Promise of Neoadjuvant Immunotherapy and Surgery for Cancer Treatment.

Efficacy, Tolerance, and Plasma Levels of Abiraterone and Its Main Metabolites in a Patient With Metastatic Castration-resistant Prostate Cancer With a Hepatic Transplant.

Building a collaboration to improve surgical research through EORTC/ESSO 1409-CLIMB study: A prospective liver metastasis database with an integrated quality assurance program.

The Drug Rediscovery protocol facilitates the expanded use of existing anticancer drugs.

Single Lesion on Prostate-specific Membrane Antigen-ligand Positron Emission Tomography and Low Prostate-specific Antigen Are Prognostic Factors for a Favorable Biochemical Response to Prostate-specific Membrane Antigen-targeted Radioguided Surgery in Recurrent Prostate Cancer.

The landscape of genomic copy number alterations in colorectal cancer and their consequences on gene expression levels and disease outcome.

Surgical Safety of Cytoreductive Nephrectomy Following Sunitinib: Results from the Multicentre, Randomised Controlled Trial of Immediate Versus Deferred Nephrectomy (SURTIME).

Correction to: Clinicians' use of breast cancer risk assessment tools according to their perceived importance of breast cancer risk factors: an international survey.

Geometrical and dosimetric evaluation of breast target volume auto-contouring.

The molecular genetic make-up of male breast cancer.

Multiparameter Flow Cytometry Assay for Quantification of Immune Cell Subsets, PD-1 Expression Levels and PD-1 Receptor Occupancy by Nivolumab and Pembrolizumab.

An international perspective on integrating physiotherapists in oncology care.

Simultaneous Quantification of Free Adalimumab and Infliximab in Human Plasma Using a Target-Based Sample Purification and Liquid Chromatography-Tandem Mass Spectrometry.

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).

A Comprehensive Network Atlas Reveals That Turing Patterns Are Common but Not Robust.

Publisher Correction: Shared heritability and functional enrichment across six solid cancers.

Sharp kinking of a coiled-coil in MutS allows DNA binding and release.

A Phase I Dose Escalation Study of Once-Weekly Oral Administration of Docetaxel as ModraDoc001 Capsule or ModraDoc006 Tablet in Combination with Ritonavir.

A fragment-like approach to PYCR1 inhibition.

Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma.

Repertoire Sequencing of B Cells Elucidates the Role of UNG and Mismatch Repair Proteins in Somatic Hypermutation in Humans.

Proteomic profiling of extracellular vesicles allows for human breast cancer subtyping.

Metabolome Analysis Reveals Dermal Histamine Accumulation in Murine Dermatitis Provoked by Genetic Deletion of P-Glycoprotein and Breast Cancer Resistance Protein.

Study protocols of three parallel phase 1 trials combining radical radiotherapy with the PARP inhibitor olaparib.

Development and validation of a liquid chromatography-tandem mass spectrometry assay for nine oral anticancer drugs in human plasma.

The ChAHP Complex Counteracts Chromatin Looping at CTCF Sites that Emerged from SINE Expansions in Mouse.

Liquid chromatography-tandem mass spectrometric assay for the quantification of galunisertib in human plasma and the application in a pre-clinical study.

Association of a Pathway-Specific Genetic Risk Score With Risk of Radiation-Associated Contralateral Breast Cancer.

P-glycoprotein Limits Ribociclib Brain Exposure and CYP3A4 Restricts Its Oral Bioavailability.

Anxiety and depression mediate the association between chemotherapy-induced peripheral neuropathy and fatigue: Results from the population-based PROFILES registry.

Usability of an online application for reporting the burden of side effects in cancer patients.

Feasibility of Micro-Computed Tomography Imaging for Direct Assessment of Surgical Resection Margins During Breast-Conserving Surgery.

MammaPrint and BluePrint Molecular Diagnostics Using Targeted RNA Next-Generation Sequencing Technology.

Individualized dosing of oral targeted therapies in oncology is crucial in the era of precision medicine.

Cytochrome P450 3A4, 3A5, and 2C8 expression in breast, prostate, lung, endometrial, and ovarian tumors: relevance for resistance to taxanes.

Pembrolizumab versus ipilimumab in advanced melanoma (KEYNOTE-006): post-hoc 5-year results from an open-label, multicentre, randomised, controlled, phase 3 study.

Assessment and management of bone health in women with early breast cancer receiving endocrine treatment in the DATA study.

MRI basics for radiation oncologists.

MRI-guided mid-position liver radiotherapy: Validation of image processing and registration steps.

Defining the Tumor Microenvironment of Penile Cancer by Means of the Cancer Immunogram.

[Imaging of rectal cancer. German version].

Getting visible with exciting IO tech!

Health-related quality of life of patients treated with chemoradiotherapy plus or minus prophylactic antibiotics to reduce the number of pneumonias for locally advanced head and neck cancer, the PANTAP study.

Multiparametric MRI Tumor Probability Model for the Detection of Locally Recurrent Prostate Cancer After Radiation Therapy: Pathologic Validation and Comparison With Manual Tumor Delineations.

Broadband hyperspectral imaging for breast tumor detection using spectral and spatial information.

Impact of organ-on-a-chip technology on pharmaceutical R&D costs.

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