Publications

Clinical pharmacokinetics

Rethinking the Application of Pemetrexed for Patients with Renal Impairment: A Pharmacokinetic Analysis.

01-05-2021

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Local control and postponement of systemic therapy after modest dose radiotherapy in oligometastatic myxoid liposarcomas.

01-05-2021

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Phase 3 Randomized Trial of Prophylactic Cranial Irradiation With or Without Hippocampus Avoidance in SCLC (NCT01780675).

01-05-2021

Key Publication

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Development of an EORTC questionnaire measuring instrumental activities of daily living (IADL) in patients with brain tumours: phase I-III.

01-05-2021

The Lancet. Oncology

Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054): distant metastasis-free survival results from a double-blind, randomised, controlled, phase 3 trial.

01-05-2021

Cancer medicine

The patient perspective in the era of personalized medicine: What about scanxiety?

01-05-2021

Nature genetics

Author Correction: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.

01-05-2021

International journal of cancer

Comprehensive trends in incidence, treatment, survival and mortality of first primary invasive breast cancer stratified by age, stage and receptor subtype in the Netherlands between 1989 and 2017.

01-05-2021

Molecular oncology

Analysing the attributes of Comprehensive Cancer Centres and Cancer Centres across Europe to identify key hallmarks.

01-05-2021

The journal of pathology. Clinical research

Detection of tumor-derived cell-free DNA from colorectal cancer peritoneal metastases in plasma and peritoneal fluid.

01-05-2021

Science advances

SMARCAD1-mediated active replication fork stability maintains genome integrity.

01-05-2021

Scandinavian journal of medicine & science in sports

Does exercise intensity matter for fatigue during (neo-)adjuvant cancer treatment? The Phys-Can randomized clinical trial.

01-05-2021

Breast cancer research and treatment

Treating (low-risk) DCIS patients: What can we learn from real-world cancer registry evidence?

01-05-2021

BMC cancer

Whole genome sequencing in oncology: using scenario drafting to explore future developments.

01-05-2021

Cancer immunology, immunotherapy : CII

Characterization of the tumor immune microenvironment in human papillomavirus-positive and -negative head and neck squamous cell carcinomas.

01-05-2021

Annals of internal medicine

Safety and Efficacy of Checkpoint Inhibition in Patients With Melanoma and Preexisting Autoimmune Disease : A Cohort Study.

01-05-2021

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

Fibrinogen Degradation Speed as a Predictor of Major Bleeding Complications During Catheter Directed Thrombolysis in Patients with Acute Lower Limb Ischaemia.

01-05-2021

European journal of cancer (Oxford, England : 1990)

Neoadjuvant ipilimumab plus nivolumab in synchronous clinical stage III melanoma.

01-05-2021

The Lancet. Oncology

Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054): health-related quality-of-life results from a double-blind, randomised, controlled, phase 3 trial.

01-05-2021

British journal of cancer

Correction: First-line BRAF/MEK inhibitors versus anti-PD-1 monotherapy in BRAF^V600-mutant advanced melanoma patients: a propensity-matched survival analysis.

01-05-2021

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Informal caregiver well-being during and after patients' treatment with adjuvant chemotherapy for colon cancer: a prospective, exploratory study.

01-05-2021

Psycho-oncology

Prevalence of cognitive impairment and change in patients with breast cancer: A systematic review of longitudinal studies.

01-05-2021

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of a combined liquid chromatography tandem-mass spectrometry assay for the quantification of aprepitant and dexamethasone in human plasma to support pharmacokinetic studies in pediatric patients.

01-05-2021

Cancer discovery

Thinking Differently about Cancer Treatment Regimens.

01-05-2021

Cancers

Immune Monitoring during Therapy Reveals Activitory and Regulatory Immune Responses in High-Risk Neuroblastoma.

26-04-2021

BMC cancer

Dedicated MRI staging versus surgical staging of peritoneal metastases in colorectal cancer patients considered for CRS-HIPEC; the DISCO randomized multicenter trial.

26-04-2021

Frontiers in oncology

Development of a Prognostic AI-Monitor for Metastatic Urothelial Cancer Patients Receiving Immunotherapy.

24-04-2021

Journal of clinical medicine

Health-Related Quality of Life Issues in Adolescents and Young Adults with Cancer: Discrepancies with the Perceptions of Health Care Professionals.

22-04-2021

Scientific reports

EGFR-dependent tyrosine phosphorylation of integrin β4 is not required for downstream signaling events in cancer cell lines.

21-04-2021

Nucleic acids research

Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites.

19-04-2021

Journal of hematology & oncology

Impact of the COVID-19 pandemic on diagnosis, stage, and initial treatment of breast cancer in the Netherlands: a population-based study.

17-04-2021

Clinical epigenetics

Identification of DNA methylation markers for early detection of CRC indicates a role for nervous system-related genes in CRC.

15-04-2021

The Journal of antimicrobial chemotherapy

Low antileishmanial drug exposure in HIV-positive visceral leishmaniasis patients on antiretrovirals: an Ethiopian cohort study.

13-04-2021

Cancers

Benign Tumors in Long-Term Survivors of Retinoblastoma.

08-04-2021

EMBO reports

Insert L1 is a central hub for allosteric regulation of USP1 activity.

07-04-2021

Frontiers in immunology

Flagellin/TLR5 Stimulate Myeloid Progenitors to Enter Lung Tissue and to Locally Differentiate Into Macrophages.

06-04-2021

Molecular & cellular proteomics : MCP

Feasibility of Phosphoproteomics on Leftover Samples After RNA Extraction With Guanidinium Thiocyanate.

06-04-2021

The Journal of molecular diagnostics : JMD

Real-World Utilization of Biomarker Testing for Patients with Advanced Non-Small Cell Lung Cancer in a Tertiary Referral Center and Referring Hospitals.

01-04-2021

The Journal of investigative dermatology

Integrin α3β1 Is a Key Regulator of Several Protumorigenic Pathways during Skin Carcinogenesis.

01-04-2021

Journal of cancer survivorship : research and practice

The course of peripheral neuropathy and its association with health-related quality of life among colorectal cancer patients.

01-04-2021

Pediatric blood & cancer

Female reproductive function after treatment of childhood acute lymphoblastic leukemia.

01-04-2021

Nature reviews. Urology

Resistance to second-generation androgen receptor antagonists in prostate cancer.

01-04-2021

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

The role of drug efflux and uptake transporters ABCB1 (P-gp), ABCG2 (BCRP) and OATP1A/1B and of CYP3A4 in the pharmacokinetics of the CDK inhibitor milciclib.

01-04-2021

ESMO open

Adolescents and young adults (AYA) with cancer: a position paper from the AYA Working Group of the European Society for Medical Oncology (ESMO) and the European Society for Paediatric Oncology (SIOPE).

01-04-2021

Cancer research

Delta-Like Ligand-Notch1 Signaling Is Selectively Modulated by HPV16 E6 to Promote Squamous Cell Proliferation and Correlates with Cervical Cancer Prognosis.

01-04-2021

Hepatology international

Checkpoint inhibitor induced hepatitis and the relation with liver metastasis and outcome in advanced melanoma patients.

01-04-2021

Current opinion in immunology

Modulation of the tumor micro-environment by CD8⁺ T cell-derived cytokines.

01-04-2021

European journal of clinical pharmacology

Correction to: Therapeutic drug monitoring of oral targeted antineoplastic drugs.

01-04-2021

Nature

Identification of bacteria-derived HLA-bound peptides in melanoma.

01-04-2021

Future oncology (London, England)

The intravenous to oral switch of taxanes: strategies and current clinical developments.

01-04-2021

Rethinking the Application of Pemetrexed for Patients with Renal Impairment: A Pharmacokinetic Analysis.

Local control and postponement of systemic therapy after modest dose radiotherapy in oligometastatic myxoid liposarcomas.

Phase 3 Randomized Trial of Prophylactic Cranial Irradiation With or Without Hippocampus Avoidance in SCLC (NCT01780675).

Development of an EORTC questionnaire measuring instrumental activities of daily living (IADL) in patients with brain tumours: phase I-III.

Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054): distant metastasis-free survival results from a double-blind, randomised, controlled, phase 3 trial.

The patient perspective in the era of personalized medicine: What about scanxiety?

Author Correction: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.

Comprehensive trends in incidence, treatment, survival and mortality of first primary invasive breast cancer stratified by age, stage and receptor subtype in the Netherlands between 1989 and 2017.

Analysing the attributes of Comprehensive Cancer Centres and Cancer Centres across Europe to identify key hallmarks.

Detection of tumor-derived cell-free DNA from colorectal cancer peritoneal metastases in plasma and peritoneal fluid.

SMARCAD1-mediated active replication fork stability maintains genome integrity.

Does exercise intensity matter for fatigue during (neo-)adjuvant cancer treatment? The Phys-Can randomized clinical trial.

Treating (low-risk) DCIS patients: What can we learn from real-world cancer registry evidence?

Whole genome sequencing in oncology: using scenario drafting to explore future developments.

Characterization of the tumor immune microenvironment in human papillomavirus-positive and -negative head and neck squamous cell carcinomas.

Safety and Efficacy of Checkpoint Inhibition in Patients With Melanoma and Preexisting Autoimmune Disease : A Cohort Study.

Fibrinogen Degradation Speed as a Predictor of Major Bleeding Complications During Catheter Directed Thrombolysis in Patients with Acute Lower Limb Ischaemia.

Neoadjuvant ipilimumab plus nivolumab in synchronous clinical stage III melanoma.

Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054): health-related quality-of-life results from a double-blind, randomised, controlled, phase 3 trial.

Correction: First-line BRAF/MEK inhibitors versus anti-PD-1 monotherapy in BRAFV600-mutant advanced melanoma patients: a propensity-matched survival analysis.

Informal caregiver well-being during and after patients' treatment with adjuvant chemotherapy for colon cancer: a prospective, exploratory study.

Prevalence of cognitive impairment and change in patients with breast cancer: A systematic review of longitudinal studies.

Development and validation of a combined liquid chromatography tandem-mass spectrometry assay for the quantification of aprepitant and dexamethasone in human plasma to support pharmacokinetic studies in pediatric patients.

Thinking Differently about Cancer Treatment Regimens.

Immune Monitoring during Therapy Reveals Activitory and Regulatory Immune Responses in High-Risk Neuroblastoma.

Dedicated MRI staging versus surgical staging of peritoneal metastases in colorectal cancer patients considered for CRS-HIPEC; the DISCO randomized multicenter trial.

Development of a Prognostic AI-Monitor for Metastatic Urothelial Cancer Patients Receiving Immunotherapy.

Health-Related Quality of Life Issues in Adolescents and Young Adults with Cancer: Discrepancies with the Perceptions of Health Care Professionals.

EGFR-dependent tyrosine phosphorylation of integrin β4 is not required for downstream signaling events in cancer cell lines.

Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites.

Impact of the COVID-19 pandemic on diagnosis, stage, and initial treatment of breast cancer in the Netherlands: a population-based study.

Identification of DNA methylation markers for early detection of CRC indicates a role for nervous system-related genes in CRC.

Low antileishmanial drug exposure in HIV-positive visceral leishmaniasis patients on antiretrovirals: an Ethiopian cohort study.

Benign Tumors in Long-Term Survivors of Retinoblastoma.

Insert L1 is a central hub for allosteric regulation of USP1 activity.

Flagellin/TLR5 Stimulate Myeloid Progenitors to Enter Lung Tissue and to Locally Differentiate Into Macrophages.

Feasibility of Phosphoproteomics on Leftover Samples After RNA Extraction With Guanidinium Thiocyanate.

Real-World Utilization of Biomarker Testing for Patients with Advanced Non-Small Cell Lung Cancer in a Tertiary Referral Center and Referring Hospitals.

Integrin α3β1 Is a Key Regulator of Several Protumorigenic Pathways during Skin Carcinogenesis.

The course of peripheral neuropathy and its association with health-related quality of life among colorectal cancer patients.

Female reproductive function after treatment of childhood acute lymphoblastic leukemia.

Resistance to second-generation androgen receptor antagonists in prostate cancer.

The role of drug efflux and uptake transporters ABCB1 (P-gp), ABCG2 (BCRP) and OATP1A/1B and of CYP3A4 in the pharmacokinetics of the CDK inhibitor milciclib.

Adolescents and young adults (AYA) with cancer: a position paper from the AYA Working Group of the European Society for Medical Oncology (ESMO) and the European Society for Paediatric Oncology (SIOPE).

Delta-Like Ligand-Notch1 Signaling Is Selectively Modulated by HPV16 E6 to Promote Squamous Cell Proliferation and Correlates with Cervical Cancer Prognosis.

Checkpoint inhibitor induced hepatitis and the relation with liver metastasis and outcome in advanced melanoma patients.

Modulation of the tumor micro-environment by CD8+ T cell-derived cytokines.

Correction to: Therapeutic drug monitoring of oral targeted antineoplastic drugs.

Identification of bacteria-derived HLA-bound peptides in melanoma.

The intravenous to oral switch of taxanes: strategies and current clinical developments.

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Correction: First-line BRAF/MEK inhibitors versus anti-PD-1 monotherapy in BRAF^V600-mutant advanced melanoma patients: a propensity-matched survival analysis.

Modulation of the tumor micro-environment by CD8⁺ T cell-derived cytokines.