Publications

Nature communications

Multi-modal generative modeling for joint analysis of single-cell T cell receptor and gene expression data.

03-07-2024

Clinical pharmacokinetics

Evaluating the Clinical Impact and Feasibility of Therapeutic Drug Monitoring of Pazopanib in a Real-World Soft-Tissue Sarcoma Cohort.

01-07-2024

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Patient-reported outcomes after personalised dose-escalation for stage II-III non-small-cell lung cancer patients: Results from the randomised ARTFORCE PET-Boost trial.

01-07-2024

Clinical pharmacokinetics

Population Pharmacokinetics of Inotuzumab Ozogamicin in Pediatric Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia: Results of Study ITCC-059.

01-07-2024

Cancer discovery

Paradoxical Activation of Oncogenic Signaling as a Cancer Treatment Strategy.

01-07-2024

The Journal of pathology

Characterization of discordance between mismatch repair deficiency and microsatellite instability testing may prevent inappropriate treatment with immunotherapy.

01-07-2024

Cancer discovery

IL2 Targeted to CD8+ T Cells Promotes Robust Effector T-cell Responses and Potent Antitumor Immunity.

01-07-2024

Cancer chemotherapy and pharmacology

Impact of loperamide on the pharmacokinetics and tissue disposition of ritonavir-boosted oral docetaxel therapy; a preclinical assessment.

01-07-2024

Cancer discovery

CD8-Targeted IL2 Unleashes Tumor-Specific Immunity in Human Cancer Tissue by Reviving the Dysfunctional T-cell Pool.

01-07-2024

The Journal of pathology

Ductal carcinoma in situ develops within clonal fields of mutant cells in morphologically normal ducts.

01-07-2024

European journal of drug metabolism and pharmacokinetics

The Use of Microdosing for In vivo Phenotyping of Cytochrome P450 Enzymes: Where Do We Stand? A Narrative Review.

01-07-2024

Nature genetics

Understanding the genetic complexity of puberty timing across the allele frequency spectrum.

01-07-2024

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

A multicentric randomized controlled phase III trial of adaptive and 18F-FDG-PET-guided dose-redistribution in locally advanced head and neck squamous cell carcinoma (ARTFORCE).

01-07-2024

Nature

Human SARS-CoV-2 challenge uncovers local and systemic response dynamics.

01-07-2024

PNAS nexus

Dual role of proliferating cell nuclear antigen monoubiquitination in facilitating Fanconi anemia-mediated interstrand crosslink repair.

01-07-2024

Cancer

Employment outcomes of adolescent and young adult cancer survivors and their partners: A Dutch population-based study.

01-07-2024

Cancer treatment reviews

Agnostic drug development revisited.

01-07-2024

FEBS letters

Nuclear receptor Nur77 and Yin-Yang 1 synergistically increase mitochondrial abundance and activity in macrophages.

01-07-2024

The Journal of antimicrobial chemotherapy

Skin pharmacokinetics of miltefosine in the treatment of post-kala-azar dermal leishmaniasis in South Asia.

01-07-2024

Medical physics

Impact of cone-beam computed tomography artifacts on dose calculation accuracy for lung cancer.

01-07-2024

Journal for immunotherapy of cancer

Mapping the complexity and diversity of tertiary lymphoid structures in primary and peritoneal metastatic gastric cancer.

01-07-2024

Physics and imaging in radiation oncology

Validation of quantitative magnetic resonance imaging techniques in head and neck healthy structures involved in the salivary and swallowing function: Accuracy and repeatability.

01-07-2024

Cancer chemotherapy and pharmacology

Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data.

01-07-2024

Cancer discovery

CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma.

01-07-2024

Psychological medicine

The mediating role of health behaviors in the association between depression, anxiety and cancer incidence: an individual participant data meta-analysis.

01-07-2024

BJU international

^99mTcPSMA-radioguided surgery in oligorecurrent prostate cancer: the randomised TRACE-II trial.

01-07-2024

Cancer discovery

Cancer Core Europe: Leveraging Institutional Synergies to Advance Oncology Research and Care Globally.

01-07-2024

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

European Society of Radiotherapy and Oncology (ESTRO) strategy 2024-2026: Growth and diversification in a rapidly changing world.

01-07-2024

Nature cell biology

Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma.

01-07-2024

Journal for immunotherapy of cancer

Autoantibody-positivity before and seroconversion during treatment with anti-PD-1 is associated with immune-related adverse events in patients with melanoma.

30-06-2024

Nature communications

Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation.

26-06-2024

Biochemical Society transactions

The choreography of chromatin in RNA polymerase III regulation.

26-06-2024

Journal of cancer research and clinical oncology

Can blood-based markers predict RECIST progression in non-small cell lung cancer treated with immunotherapy?

26-06-2024

Cell reports

Gene and protein sequence features augment HLA class I ligand predictions.

25-06-2024

Journal of mammary gland biology and neoplasia

Transcriptomic Analysis of Pubertal and Adult Virgin Mouse Mammary Epithelial and Stromal Cell Populations.

25-06-2024

Journal of mammary gland biology and neoplasia

Rat Models of Hormone Receptor-Positive Breast Cancer.

24-06-2024

Lancet (London, England)

Ductal carcinoma in situ of the breast: finding the balance between overtreatment and undertreatment.

22-06-2024

Nature communications

Widespread chromatin context-dependencies of DNA double-strand break repair proteins.

22-06-2024

iScience

Predicting treatment outcome using kinome activity profiling in HER2+ breast cancer biopsies.

21-06-2024

Scientific reports

Cox proportional hazards regression in small studies of predictive biomarkers.

20-06-2024

NPJ digital medicine

PatchSorter: a high throughput deep learning digital pathology tool for object labeling.

20-06-2024

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Use of Sodium Thiosulfate as an Otoprotectant in Patients With Cancer Treated With Platinum Compounds: A Review of the Literature.

20-06-2024

Cell reports. Medicine

The impact of ATP-binding cassette transporters in the diseased brain: Context matters.

18-06-2024

The British journal of radiology

Imaging in the era of risk-adapted treatment in colon cancer.

18-06-2024

Journal of pharmaceutical and biomedical analysis

A multiplex UPLC-MS/MS method for the quantification of three PD-L1 checkpoint inhibitors, atezolizumab, avelumab, and durvalumab, in human serum.

15-06-2024

Nature communications

UBE2D3 facilitates NHEJ by orchestrating ATM signalling through multi-level control of RNF168.

12-06-2024

Cancer cell

The case for therapeutic overactivation of oncogenic signaling as a potential cancer treatment strategy.

10-06-2024

The New England journal of medicine

Neoadjuvant Immunotherapy in Locally Advanced Mismatch Repair-Deficient Colon Cancer.

06-06-2024

Molecular cancer

Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients.

04-06-2024

bioRxiv : the preprint server for biology

Automated classification of cellular expression in multiplexed imaging data with Nimbus.

03-06-2024

Multi-modal generative modeling for joint analysis of single-cell T cell receptor and gene expression data.

Evaluating the Clinical Impact and Feasibility of Therapeutic Drug Monitoring of Pazopanib in a Real-World Soft-Tissue Sarcoma Cohort.

Patient-reported outcomes after personalised dose-escalation for stage II-III non-small-cell lung cancer patients: Results from the randomised ARTFORCE PET-Boost trial.

Population Pharmacokinetics of Inotuzumab Ozogamicin in Pediatric Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia: Results of Study ITCC-059.

Paradoxical Activation of Oncogenic Signaling as a Cancer Treatment Strategy.

Characterization of discordance between mismatch repair deficiency and microsatellite instability testing may prevent inappropriate treatment with immunotherapy.

IL2 Targeted to CD8+ T Cells Promotes Robust Effector T-cell Responses and Potent Antitumor Immunity.

Impact of loperamide on the pharmacokinetics and tissue disposition of ritonavir-boosted oral docetaxel therapy; a preclinical assessment.

CD8-Targeted IL2 Unleashes Tumor-Specific Immunity in Human Cancer Tissue by Reviving the Dysfunctional T-cell Pool.

Ductal carcinoma in situ develops within clonal fields of mutant cells in morphologically normal ducts.

The Use of Microdosing for In vivo Phenotyping of Cytochrome P450 Enzymes: Where Do We Stand? A Narrative Review.

Understanding the genetic complexity of puberty timing across the allele frequency spectrum.

A multicentric randomized controlled phase III trial of adaptive and 18F-FDG-PET-guided dose-redistribution in locally advanced head and neck squamous cell carcinoma (ARTFORCE).

Human SARS-CoV-2 challenge uncovers local and systemic response dynamics.

Dual role of proliferating cell nuclear antigen monoubiquitination in facilitating Fanconi anemia-mediated interstrand crosslink repair.

Employment outcomes of adolescent and young adult cancer survivors and their partners: A Dutch population-based study.

Agnostic drug development revisited.

Nuclear receptor Nur77 and Yin-Yang 1 synergistically increase mitochondrial abundance and activity in macrophages.

Skin pharmacokinetics of miltefosine in the treatment of post-kala-azar dermal leishmaniasis in South Asia.

Impact of cone-beam computed tomography artifacts on dose calculation accuracy for lung cancer.

Mapping the complexity and diversity of tertiary lymphoid structures in primary and peritoneal metastatic gastric cancer.

Validation of quantitative magnetic resonance imaging techniques in head and neck healthy structures involved in the salivary and swallowing function: Accuracy and repeatability.

Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data.

CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma.

The mediating role of health behaviors in the association between depression, anxiety and cancer incidence: an individual participant data meta-analysis.

99mTcPSMA-radioguided surgery in oligorecurrent prostate cancer: the randomised TRACE-II trial.

Cancer Core Europe: Leveraging Institutional Synergies to Advance Oncology Research and Care Globally.

European Society of Radiotherapy and Oncology (ESTRO) strategy 2024-2026: Growth and diversification in a rapidly changing world.

Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma.

Autoantibody-positivity before and seroconversion during treatment with anti-PD-1 is associated with immune-related adverse events in patients with melanoma.

Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation.

The choreography of chromatin in RNA polymerase III regulation.

Can blood-based markers predict RECIST progression in non-small cell lung cancer treated with immunotherapy?

Gene and protein sequence features augment HLA class I ligand predictions.

Transcriptomic Analysis of Pubertal and Adult Virgin Mouse Mammary Epithelial and Stromal Cell Populations.

Rat Models of Hormone Receptor-Positive Breast Cancer.

Ductal carcinoma in situ of the breast: finding the balance between overtreatment and undertreatment.

Widespread chromatin context-dependencies of DNA double-strand break repair proteins.

Predicting treatment outcome using kinome activity profiling in HER2+ breast cancer biopsies.

Cox proportional hazards regression in small studies of predictive biomarkers.

PatchSorter: a high throughput deep learning digital pathology tool for object labeling.

Use of Sodium Thiosulfate as an Otoprotectant in Patients With Cancer Treated With Platinum Compounds: A Review of the Literature.

The impact of ATP-binding cassette transporters in the diseased brain: Context matters.

Imaging in the era of risk-adapted treatment in colon cancer.

A multiplex UPLC-MS/MS method for the quantification of three PD-L1 checkpoint inhibitors, atezolizumab, avelumab, and durvalumab, in human serum.

UBE2D3 facilitates NHEJ by orchestrating ATM signalling through multi-level control of RNF168.

The case for therapeutic overactivation of oncogenic signaling as a potential cancer treatment strategy.

Neoadjuvant Immunotherapy in Locally Advanced Mismatch Repair-Deficient Colon Cancer.

Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients.

Automated classification of cellular expression in multiplexed imaging data with Nimbus.

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^99mTcPSMA-radioguided surgery in oligorecurrent prostate cancer: the randomised TRACE-II trial.