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Knockdown stands up.

P Mathijs Voorhoeve ,
Reuven Agami

Abstract

In the past year, the genetic research of mammalian cells in vitro has gained the advantages of RNA interference (RNAi), a process found in worms and plants by which double stranded RNAs mediate selective gene inactivation through mRNA destruction. Recently, two papers have shown that genes could be suppressed in vivo in mammals by RNAi, which has potential implications for both therapeutics and research.

More about this publication

Trends in biotechnology

Volume 21
Issue nr. 1
Pages 2-4
Publication date 01-01-2003

Full text links

Publisher website (DOI) 10.1016/s0167-7799(02)00002-1
Europe PubMed Central 12480342
Pubmed 12480342

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