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Application of PET/CT in the development of novel anticancer drugs.

David S Boss ,
Renato Valdes Olmos ,
Michiel Sinaasappel ,
Jos H Beijnen ,
Jan H M Schellens

Abstract

Combined positron emission tomography/computed tomography (PET/CT) is a relatively new imaging modality, combining the functional images of PET with the anatomical information of CT. Since its commercial introduction about 5 years ago, PET/CT has become an important tool in oncology. Currently, the technique is used for primary staging and restaging of cancer patients, as well as for surgery and radiation therapy planning. The abilities of PET/CT to measure early treatment response as well as drug distribution within the body make this technique very useful in the development of novel anticancer drugs. In this paper, the recent literature on the current role of PET/CT in drug development is reviewed.

More about this publication

The oncologist

Volume 13
Issue nr. 1
Pages 25-38
Publication date 01-01-2008

Full text links

Publisher website (DOI) 10.1634/theoncologist.2007-0097
Europe PubMed Central 18245010
Pubmed 18245010

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