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Surgical wound complications after groin dissection in melanoma patients - a historical cohort study and risk factor analysis.

M M Stuiver ,
E Westerduin ,
S ter Meulen ,
A D Vincent ,
O E Nieweg ,
M W J M Wouters

Abstract

METHODS

A chart review was conducted of all patients on whom inguinal lymph node dissection had been performed between 2003 and 2013. Wound infections, seroma formation and skin flap problems were assessed according to explicit definitions and graded through the modified Clavien system. Univariable and multivariable penalized logistic regression was used to identify risk factors. The primary factors of interest were body mass index, age, smoking, diabetes, cardiovascular and/or pulmonal comorbidity, palpable disease and postoperative bedrest. Additionally, the influence of incision-type, sartorius transposition, saphenous vein sparing and skin removal was examined.

CONCLUSIONS

Wound complication rates after ILND in melanoma patients are high. Age was the only predictor of complications in this cohort, other previously identified risk factors could not be confirmed.

RESULTS

A total of 145 procedures was examined. One or more complications occurred in 104 (72%) of the procedures; wound infection in 45%, seroma formation in 37% and skin flap problems in 26%. The only statistically significant risk factor was age (odds ratio for one standard deviation increase: 1.46, 95%CI 1.01-2.14, p = 0.05).

BACKGROUND AND OBJECTIVES

Wound complications occur frequently after inguinal lymph node dissection (ILND) in melanoma patients. Evidence on risk factors for complications is scarce and inconsistent. This study assessed wound complication rates after ILND and investigated associated risk factors, in the melanoma unit of a specialised cancer hospital.

More about this publication

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Volume 40
Issue nr. 10
Pages 1284-90
Publication date 01-10-2014

Full text links

Publisher website (DOI) 10.1016/j.ejso.2014.01.019
Europe PubMed Central 24612654
Pubmed 24612654

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