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Dynamic collimator angle adjustments during volumetric modulated arc therapy to account for prostate rotations.

Johan de Boer ,
Anne Lisa Wolf ,
Yenny Z Szeto ,
Marcel van Herk ,
Jan-Jakob Sonke

Abstract

METHODS AND MATERIALS

Clinical VMAT treatment plans of 5 prostate cancer patients were used. Simulated left-right prostate rotations between +15° and -15° were corrected by collimator rotations. We compared corrected and uncorrected plans by dose volume histograms, minimum dose (Dmin) to the prostate, bladder surface receiving ≥78 Gy (S78) and rectum equivalent uniform dose (EUD; n=0.13). Each corrected plan was delivered to a phantom, and its deliverability was evaluated by γ-evaluation between planned and delivered dose, which was reconstructed from portal images acquired during delivery.

CONCLUSIONS

It is feasible to dynamically adjust the collimator angle during VMAT treatment delivery to correct for prostate rotations. This technique can safely correct for left-right prostate rotations up to 15°.

RESULTS

On average, clinical target volume minimum dose (Dmin) decreased up to 10% without corrections. Negative left-right rotations were corrected almost perfectly, whereas Dmin remained within 4% for positive rotations. Bladder S78 and rectum EUD of the corrected plans matched those of the original plans. The average pass rate for the corrected plans delivered to the phantom was 98.9% at 3% per 3 mm gamma criteria. The measured dose in the planning target volume approximated the original dose, rotated around the simulated left-right angle, well.

PURPOSE

Rotations of the prostate gland induce considerable geometric uncertainties in prostate cancer radiation therapy. Collimator and gantry angle adjustments can correct these rotations in intensity modulated radiation therapy. Modern volumetric modulated arc therapy (VMAT) treatments, however, include a wide range of beam orientations that differ in modulation, and corrections require dynamic collimator rotations. The aim of this study was to implement a rotation correction strategy for VMAT dose delivery and validate it for left-right prostate rotations.

More about this publication

International journal of radiation oncology, biology, physics

Volume 91
Issue nr. 5
Pages 1009-16
Publication date 01-04-2015

Full text links

Publisher website (DOI) 10.1016/j.ijrobp.2014.11.020
Europe PubMed Central 25618782
Pubmed 25618782

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