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Molecular tumour boards and molecular diagnostics for patients with cancer in the Netherlands: experiences, challenges, and aspirations.

Annelieke E C A B Willemsen ,
Sarah Krausz ,
Marjolijn J L Ligtenberg ,
Katrien Grünberg ,
Harry J M Groen ,
Emile E Voest ,
Edwin P J G Cuppen ,
Hanneke W M van Laarhoven ,
Carla M L van Herpen

Abstract

Advances in molecular tumour diagnostics and the number of targeted therapies increase rapidly. Molecular tumour boards (MTBs) are designated to interpret these data and provide clinical recommendations. Not all patients with cancer have access to advice of an MTB. We aimed to determine the current status, opportunities, and challenges of the organisation of MTBs in the Netherlands. We interviewed several stakeholders about their experiences with an MTB, using template analysis. Most clinicians and patient representatives underscore the significance of an MTB, because it can stimulate rational treatment options, enrolment in clinical trials, and interdisciplinary knowledge transfer. Health insurance companies and financial managers are concerned about increasing costs. Registries to assess the clinical benefit of MTBs, guidelines on quality control, financial agreements, and logistical resources are lacking. The national organisation of MTBs and a registry of molecular and clinical data are important issues to address.

More about this publication

British journal of cancer

Volume 121
Issue nr. 1
Pages 34-36
Publication date 01-07-2019

Full text links

Publisher website (DOI) 10.1038/s41416-019-0489-3
Europe PubMed Central 31130724
Pubmed 31130724

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