Life in the (Pluripotent) Fast Lane: Cdk1 Preserves the Epigenome to Maintain Pluripotency.

Abstract

Michowski and colleagues (2020) engineered analog-sensitive Cdk1 knockin mice to identify Cdk1 targets in embryonic stem cells, which led them to discover a novel function for Cdk1 in shaping the epigenetic landscape by direct regulation of epigenetic modulators.

More about this publication

Molecular cell
  • Volume 78
  • Issue nr. 3
  • Pages 374-375
  • Publication date 07-05-2020

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