Coordinated cancer chaos.


Stochastic processes, such as genetic instability and microenvironment evolution, drive tumor heterogeneity, thereby creating the chaotic appearance of tumors in histopathology. In this issue of Cell, Lin et al. reveal that tumors are surprisingly spatially organized from a molecular to tissue scale, indicating that cancers evolve as autonomously patterned systems.

More about this publication

  • Volume 186
  • Issue nr. 2
  • Pages 235-237
  • Publication date 19-01-2023

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