Publications

European journal of immunology

Acidity-mediated induction of FoxP3⁺ regulatory T cells.

01-06-2023

Cancer chemotherapy and pharmacology

Exposure-response analyses of BRAF- and MEK-inhibitors dabrafenib plus trametinib in melanoma patients.

01-06-2023

Cancer medicine

Phase II study (KAMELEON) of single-agent T-DM1 in patients with HER2-positive advanced urothelial bladder cancer or pancreatic cancer/cholangiocarcinoma.

01-06-2023

Nature medicine

Neoadjuvant immunotherapy for melanoma is now ready for clinical practice.

01-06-2023

Nature structural & molecular biology

Structural basis of centromeric cohesion protection.

01-06-2023

Journal of neuro-oncology

Optimizing treatment of brain metastases in an era of novel systemic treatments: a single center consecutive series.

01-06-2023

Journal of immunotherapy (Hagerstown, Md. : 1997)

Real-world Outcomes of Ipilimumab Plus Nivolumab Combination Therapy in a Nation-wide Cohort of Advanced Melanoma Patients in the Netherlands.

01-06-2023

Annals of epidemiology

The Areola study: design and rationale of a cohort study on long-term health outcomes in women with implant-based breast reconstructions.

01-06-2023

Acta crystallographica. Section D, Structural biology

The CCP4 suite: integrative software for macromolecular crystallography.

01-06-2023

European journal of cancer (Oxford, England : 1990)

Duty to recontact in genomic cancer care: A tool helping to assess the professional's responsibility.

01-06-2023

Breast (Edinburgh, Scotland)

Patients' experiences with pre-test genetic counseling provided by breast cancer healthcare professionals: Results from a large prospective multicenter study.

01-06-2023

Virchows Archiv : an international journal of pathology

Comparison of NTRK fusion detection methods in microsatellite-instability-high metastatic colorectal cancer.

01-06-2023

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

A simple extemporaneous oral suspension of aprepitant yields sufficient pharmacokinetic exposure in children.

01-06-2023

European radiology

Comparison of MRI response evaluation methods in rectal cancer: a multicentre and multireader validation study.

01-06-2023

European journal of cancer (Oxford, England : 1990)

Defining the role of real-world data in cancer clinical research: The position of the European Organisation for Research and Treatment of Cancer.

01-06-2023

Annals of surgical oncology

ASO Visual Abstract: Surgical Oncologists and Nurses in Breast Cancer Care are Ready to Provide Pre-Test Genetic Counseling.

01-06-2023

Nature reviews. Clinical oncology

Personalizing neoadjuvant immune-checkpoint inhibition in patients with melanoma.

01-06-2023

Therapeutic drug monitoring

Development of a Therapeutic Drug Monitoring Strategy for the Optimization of Vincristine Treatment in Pediatric Oncology Populations in Africa.

01-06-2023

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Ion suppression, reduced long-term robustness and leakage current of the spray voltage during the ionization of trichloroacetic acid; a case study with a methylmalonic acid assay.

30-05-2023

Cell reports

MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells.

30-05-2023

Cell reports

Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1- versus BRCA2-deficient mammary tumors.

30-05-2023

Cancers

Treating Primary Node-Positive Prostate Cancer: A Scoping Review of Available Treatment Options.

29-05-2023

Radiation oncology (London, England)

Deep learning for segmentation of the cervical cancer gross tumor volume on magnetic resonance imaging for brachytherapy.

29-05-2023

Cancers

A Survival Tree of Advanced Melanoma Patients with Brain Metastases Treated with Immune Checkpoint Inhibitors.

26-05-2023

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Psychological and social challenges of patients with locally advanced and metastatic gastrointestinal stromal tumours (GIST) on long-term treatment with tyrosine kinase inhibitors: a qualitative study with patients and medical oncologists.

26-05-2023

Molecular cell

DNA supercoiling restricts the transcriptional bursting of neighboring eukaryotic genes.

18-05-2023

Micromachines

Microcamera Visualisation System to Overcome Specular Reflections for Tissue Imaging.

17-05-2023

The British journal of surgery

Oncological surgery follow-up and quality of life: meta-analysis.

16-05-2023

BMC medical research methodology

The Trial within Cohorts (TwiCs) study design in oncology: experience and methodological reflections.

13-05-2023

NPJ breast cancer

Immune landscape of breast tumors with low and intermediate estrogen receptor expression.

13-05-2023

NPJ breast cancer

PREDICT validity for prognosis of breast cancer patients with pathogenic BRCA1/2 variants.

12-05-2023

Pharmaceutics

Optimization of a Quantitative Anti-Drug Antibodies against Infliximab Assay with the Liquid Chromatography-Tandem Mass Spectrometry: A Method Validation Study and Future Perspectives.

12-05-2023

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

High-Grade Serous Carcinoma at Risk-Reducing Salpingo-Oophorectomy in Asymptomatic Carriers of BRCA1/2 Pathogenic Variants: Prevalence and Clinical Factors.

10-05-2023

Cancers

Tissue Classification of Breast Cancer by Hyperspectral Unmixing.

09-05-2023

Breast cancer research : BCR

Breast cancer genomes from CHEK2 c.1100delC mutation carriers lack somatic TP53 mutations and display a unique structural variant size distribution profile.

09-05-2023

Cancer cell

A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression.

08-05-2023

Breast cancer research : BCR

Systematic screening identifies ABCG2 as critical factor underlying synergy of kinase inhibitors with transcriptional CDK inhibitors.

05-05-2023

Molecular cell

PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1.

04-05-2023

Cold Spring Harbor perspectives in medicine

Multidimensional Imaging of Breast Cancer.

02-05-2023

PloS one

A deep learning-based application for COVID-19 diagnosis on CT: The Imaging COVID-19 AI initiative.

02-05-2023

Clinical and translational medicine

Drug-drug synthetic lethality to combat cancer: From bench to bedside.

01-05-2023

Nature structural & molecular biology

Dynamic epistasis analysis reveals how chromatin remodeling regulates transcriptional bursting.

01-05-2023

European journal of cancer (Oxford, England : 1990)

Definition, diagnosis and treatment of oligometastatic oesophagogastric cancer: A Delphi consensus study in Europe.

01-05-2023

EClinicalMedicine

Influence of germline variations in drug transporters ABCB1 and ABCG2 on intracerebral osimertinib efficacy in patients with non-small cell lung cancer.

01-05-2023

Pharmaceutical research

Exposure-Response Analyses of Olaparib in Real-Life Patients with Ovarian Cancer.

01-05-2023

Molecular pharmaceutics

Enhancement of the Oral Availability of Cabazitaxel Using the Cytochrome P450 3A (CYP3A) Inhibitor Ritonavir in Mice.

01-05-2023

Pediatric blood & cancer

Clinical evaluation of late outcomes in Dutch childhood cancer survivors: Methodology of the DCCSS LATER 2 study.

01-05-2023

Veterinary pathology

Spontaneous early-onset neurodegeneration in the brainstem and spinal cord of NSG, NOG, and NXG mice.

01-05-2023

Haematologica

Pathology review identifies frequent misdiagnoses in recurrent classic Hodgkin lymphoma in a nationwide cohort: implications for clinical and epidemiological studies.

01-05-2023

Journal of lipid research

Role of enterocyte Enpp2 and autotaxin in regulating lipopolysaccharide levels, systemic inflammation, and atherosclerosis.

01-05-2023

Acidity-mediated induction of FoxP3+ regulatory T cells.

Exposure-response analyses of BRAF- and MEK-inhibitors dabrafenib plus trametinib in melanoma patients.

Phase II study (KAMELEON) of single-agent T-DM1 in patients with HER2-positive advanced urothelial bladder cancer or pancreatic cancer/cholangiocarcinoma.

Neoadjuvant immunotherapy for melanoma is now ready for clinical practice.

Structural basis of centromeric cohesion protection.

Optimizing treatment of brain metastases in an era of novel systemic treatments: a single center consecutive series.

Real-world Outcomes of Ipilimumab Plus Nivolumab Combination Therapy in a Nation-wide Cohort of Advanced Melanoma Patients in the Netherlands.

The Areola study: design and rationale of a cohort study on long-term health outcomes in women with implant-based breast reconstructions.

The CCP4 suite: integrative software for macromolecular crystallography.

Duty to recontact in genomic cancer care: A tool helping to assess the professional's responsibility.

Patients' experiences with pre-test genetic counseling provided by breast cancer healthcare professionals: Results from a large prospective multicenter study.

Comparison of NTRK fusion detection methods in microsatellite-instability-high metastatic colorectal cancer.

A simple extemporaneous oral suspension of aprepitant yields sufficient pharmacokinetic exposure in children.

Comparison of MRI response evaluation methods in rectal cancer: a multicentre and multireader validation study.

Defining the role of real-world data in cancer clinical research: The position of the European Organisation for Research and Treatment of Cancer.

ASO Visual Abstract: Surgical Oncologists and Nurses in Breast Cancer Care are Ready to Provide Pre-Test Genetic Counseling.

Personalizing neoadjuvant immune-checkpoint inhibition in patients with melanoma.

Development of a Therapeutic Drug Monitoring Strategy for the Optimization of Vincristine Treatment in Pediatric Oncology Populations in Africa.

Ion suppression, reduced long-term robustness and leakage current of the spray voltage during the ionization of trichloroacetic acid; a case study with a methylmalonic acid assay.

MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells.

Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1- versus BRCA2-deficient mammary tumors.

Treating Primary Node-Positive Prostate Cancer: A Scoping Review of Available Treatment Options.

Deep learning for segmentation of the cervical cancer gross tumor volume on magnetic resonance imaging for brachytherapy.

A Survival Tree of Advanced Melanoma Patients with Brain Metastases Treated with Immune Checkpoint Inhibitors.

Psychological and social challenges of patients with locally advanced and metastatic gastrointestinal stromal tumours (GIST) on long-term treatment with tyrosine kinase inhibitors: a qualitative study with patients and medical oncologists.

DNA supercoiling restricts the transcriptional bursting of neighboring eukaryotic genes.

Microcamera Visualisation System to Overcome Specular Reflections for Tissue Imaging.

Oncological surgery follow-up and quality of life: meta-analysis.

The Trial within Cohorts (TwiCs) study design in oncology: experience and methodological reflections.

Immune landscape of breast tumors with low and intermediate estrogen receptor expression.

PREDICT validity for prognosis of breast cancer patients with pathogenic BRCA1/2 variants.

Optimization of a Quantitative Anti-Drug Antibodies against Infliximab Assay with the Liquid Chromatography-Tandem Mass Spectrometry: A Method Validation Study and Future Perspectives.

High-Grade Serous Carcinoma at Risk-Reducing Salpingo-Oophorectomy in Asymptomatic Carriers of BRCA1/2 Pathogenic Variants: Prevalence and Clinical Factors.

Tissue Classification of Breast Cancer by Hyperspectral Unmixing.

Breast cancer genomes from CHEK2 c.1100delC mutation carriers lack somatic TP53 mutations and display a unique structural variant size distribution profile.

A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression.

Systematic screening identifies ABCG2 as critical factor underlying synergy of kinase inhibitors with transcriptional CDK inhibitors.

PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1.

Multidimensional Imaging of Breast Cancer.

A deep learning-based application for COVID-19 diagnosis on CT: The Imaging COVID-19 AI initiative.

Drug-drug synthetic lethality to combat cancer: From bench to bedside.

Dynamic epistasis analysis reveals how chromatin remodeling regulates transcriptional bursting.

Definition, diagnosis and treatment of oligometastatic oesophagogastric cancer: A Delphi consensus study in Europe.

Influence of germline variations in drug transporters ABCB1 and ABCG2 on intracerebral osimertinib efficacy in patients with non-small cell lung cancer.

Exposure-Response Analyses of Olaparib in Real-Life Patients with Ovarian Cancer.

Enhancement of the Oral Availability of Cabazitaxel Using the Cytochrome P450 3A (CYP3A) Inhibitor Ritonavir in Mice.

Clinical evaluation of late outcomes in Dutch childhood cancer survivors: Methodology of the DCCSS LATER 2 study.

Spontaneous early-onset neurodegeneration in the brainstem and spinal cord of NSG, NOG, and NXG mice.

Pathology review identifies frequent misdiagnoses in recurrent classic Hodgkin lymphoma in a nationwide cohort: implications for clinical and epidemiological studies.

Role of enterocyte Enpp2 and autotaxin in regulating lipopolysaccharide levels, systemic inflammation, and atherosclerosis.

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Acidity-mediated induction of FoxP3⁺ regulatory T cells.