Publications

Nature cell biology

Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response.

01-04-2019

Key

Cancer research communications

Combined Inhibition of EZH2 and FGFR is Synergistic in BAP1-deficient Malignant Mesothelioma.

03-01-2024

Science advances

BCRP drives intrinsic chemoresistance in chemotherapy-naïve breast cancer brain metastasis.

20-10-2023

Nature

Identification of an alternative triglyceride biosynthesis pathway.

01-09-2023

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Natural deletion of mouse carboxylesterases Ces1c/d/e impacts drug metabolism and metabolic syndrome development.

01-08-2023

International journal of molecular sciences

A C57BL/6J Fancg-KO Mouse Model Generated by CRISPR/Cas9 Partially Captures the Human Phenotype.

05-07-2023

Molecular oncology

Rational combination of SHP2 and mTOR inhibition for the treatment of hepatocellular carcinoma.

01-06-2023

Molecular cancer research : MCR

The Elongin BC Complex Negatively Regulates AXL and Marks a Differentiated Phenotype in Melanoma.

01-05-2023

Archives of gynecology and obstetrics

Effects of chemotherapy on ovaries of pregnant mice.

01-04-2023

Nature communications

Author Correction: Reversal of pre-existing NGFR-driven tumor and immune therapy resistance.

07-02-2023

Proceedings of the National Academy of Sciences of the United States of America

Mammalian life depends on two distinct pathways of DNA damage tolerance.

24-01-2023

Cell reports. Medicine

Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis.

15-11-2022

Nature cancer

cFLIP suppression and DR5 activation sensitize senescent cancer cells to senolysis.

01-11-2022

The Journal of pathology

R-spondin-3 is an oncogenic driver of poorly differentiated invasive breast cancer.

01-11-2022

Science (New York, N.Y.)

Actin maturation requires the ACTMAP/C19orf54 protease.

30-09-2022

PloS one

Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity.

07-09-2022

Nature

Truncated FGFR2 is a clinically actionable oncogene in multiple cancers.

10-08-2022

Nucleic acids research

Division of labor within the DNA damage tolerance system reveals non-epistatic and clinically actionable targets for precision cancer medicine.

22-07-2022

Science (New York, N.Y.)

Posttranslational modification of microtubules by the MATCAP detyrosinase.

20-05-2022

Clinical cancer research : an official journal of the American Association for Cancer Research

Predictive Immune-Checkpoint Blockade Classifiers Identify Tumors Responding to Inhibition of PD-1 and/or CTLA-4.

01-10-2021

Cancer research

Cooperative Targeting of Immunotherapy-Resistant Melanoma and Lung Cancer by an AXL-Targeting Antibody-Drug Conjugate and Immune Checkpoint Blockade.

01-04-2021

EMBO reports

Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation.

03-02-2021

Cell reports

USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells.

29-12-2020

Nature communications

Reversal of pre-existing NGFR-driven tumor and immune therapy resistance.

07-08-2020

Pharmacology research & perspectives

No relation between docetaxel administration route and high-grade diarrhea incidence.

01-08-2020

Life science alliance

Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis.

01-07-2020

Proceedings of the National Academy of Sciences of the United States of America

Uncoupling DNA damage from chromatin damage to detoxify doxorubicin.

30-06-2020

Nature immunology

Author Correction: Tissue patrol by resident memory CD8⁺ T cells in human skin.

01-06-2020

The Journal of experimental medicine

Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice.

01-06-2020

Communications biology

A mouse model that is immunologically tolerant to reporter and modifier proteins.

29-05-2020

PloS one

Gene expression regulation by the Chromodomain helicase DNA-binding protein 9 (CHD9) chromatin remodeler is dispensable for murine development.

27-05-2020

Cell reports

FGFR1 Oncogenic Activation Reveals an Alternative Cell of Origin of SCLC in Rb1/p53 Mice.

17-03-2020

Nature communications

Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism.

28-02-2020

Radiation oncology (London, England)

Evaluation of acute esophageal radiation-induced damage using magnetic resonance imaging: a feasibility study in mice.

30-10-2019

The EMBO journal

SLC1A3 contributes to L-asparaginase resistance in solid tumors.

04-10-2019

Nature communications

Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma.

13-09-2019

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Micro cone beam computed tomography for sensitive assessment of radiation-induced late lung toxicity in preclinical models.

01-09-2019

Journal of biophotonics

Optical coherence tomography to detect acute esophageal radiation-induced damage in mice: A validation study.

01-09-2019

Cell reports

Tumor Heterogeneity Underlies Differential Cisplatin Sensitivity in Mouse Models of Small-Cell Lung Cancer.

11-06-2019

Nature immunology

Tissue patrol by resident memory CD8⁺ T cells in human skin.

01-06-2019

Breast cancer research : BCR

Absence of integrin α3β1 promotes the progression of HER2-driven breast cancer in vivo.

17-05-2019

Nature communications

A natural WNT signaling variant potently synergizes with Cdkn2ab loss in skin carcinogenesis.

29-03-2019

Archives of toxicology

ABC transporters Mdr1a/1b, Bcrp1, Mrp2 and Mrp3 determine the sensitivity to PhIP/DSS-induced colon carcinogenesis and inflammation.

01-03-2019

PloS one

Towards an understanding of C9orf82 protein/CAAP1 function.

11-01-2019

BMC bioinformatics

XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data.

04-10-2018

British journal of cancer

Mps1 inhibitors synergise with low doses of taxanes in promoting tumour cell death by enhancement of errors in cell division.

01-06-2018

Cell

An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential.

31-05-2018

Journal of biomedical optics

Feasibility of using optical coherence tomography to detect acute radiation-induced esophageal damage in small animal models.

01-04-2018

Nature medicine

Cooperative targeting of melanoma heterogeneity with an AXL antibody-drug conjugate and BRAF/MEK inhibitors.

01-02-2018

Development (Cambridge, England)

Knockout of the Arp2/3 complex in epidermis causes a psoriasis-like disease hallmarked by hyperactivation of transcription factor Nrf2.

15-12-2017