Publications

Breast cancer research and treatment

Dual-modality breast cancer screening compared to MRI or mammography alone among female Hodgkin lymphoma survivors who received chest radiotherapy.

28-01-2026

Proceedings of the National Academy of Sciences of the United States of America

An accurate cellular assay to determine pathogenicity of coding and noncoding variants in Lynch syndrome genes.

20-01-2026

Statistics in medicine

Multiple Testing of Mix-and-Match Feature Sets in Multi-Omics.

01-01-2026

The Lancet. Digital health

Label-efficient computational tumour infiltrating lymphocyte assessment in breast cancer (ECTIL): multicentre validation in 2340 patients with breast cancer.

01-11-2025

Annals of oncology : official journal of the European Society for Medical Oncology

Health-related quality of life of patients with metastatic melanoma treated with tumor-infiltrating lymphocytes compared with ipilimumab in a randomized phase III trial.

01-10-2025

Nature communications

Reanalysis of in vivo drug synergy validation study rules out synergy in most cases.

30-09-2025

Cell reports. Medicine

Epigenetic profiling identifies markers of endocrine resistance and therapeutic options for metastatic castration-resistant prostate cancer.

15-07-2025

JCI insight

G6PC3 promotes genome maintenance and is a candidate mammary tumor suppressor.

09-06-2025

The Journal of clinical investigation

The class II myosin MYH4 safeguards genome integrity and suppresses tumor progression.

02-06-2025

ESMO open

Financial toxicity and socioeconomic impact of cancer in Europe.

01-06-2025

NPJ precision oncology

A morphometric signature to identify ductal carcinoma in situ with a low risk of progression.

28-01-2025

Nature

The oestrous cycle stage affects mammary tumour sensitivity to chemotherapy.

01-01-2025

European radiology

Artificial intelligence-assisted double reading of chest radiographs to detect clinically relevant missed findings: a two-centre evaluation.

01-09-2024

Nature

Mechanisms that clear mutations drive field cancerization in mammary tissue.

01-09-2024

iScience

Predictive gene expression profile for adjuvant taxane benefit in breast cancer in the MATADOR trial.

16-08-2024

BMC bioinformatics

A new approach to describe the taxonomic structure of microbiome and its application to assess the relationship between microbial niches.

05-02-2024

Research square

Artificial intelligence-based morphometric signature to identify ductal carcinoma in situ with low risk of progression to invasive breast cancer.

13-12-2023

Molecular cell

Locus-specific proteome decoding reveals Fpt1 as a chromatin-associated negative regulator of RNA polymerase III assembly.

07-12-2023

Journal of dental research

Microbial Indicators of Dental Health, Dysbiosis, and Early Childhood Caries.

01-07-2023

Cancer cell

Taxanes trigger cancer cell killing in vivo by inducing non-canonical T cell cytotoxicity.

12-06-2023

Radiology. Cardiothoracic imaging

Artificial Intelligence Tool for Detection and Worklist Prioritization Reduces Time to Diagnosis of Incidental Pulmonary Embolism at CT.

01-04-2023

BMC bioinformatics

ShrinkCRISPR: a flexible method for differential fitness analysis of CRISPR-Cas9 screen data.

03-02-2023

Communications biology

Genome-wide siRNA screens identify RBBP9 function as a potential target in Fanconi anaemia-deficient head-and-neck squamous cell carcinoma.

13-01-2023

Biometrical journal. Biometrische Zeitschrift

A powerful global test for spliceQTL effects.

01-01-2023

Sensors (Basel, Switzerland)

Electronic Nose Sensor Drift Affects Diagnostic Reliability and Accuracy of Disease-Specific Algorithms.

28-11-2022

Frontiers in genetics

Editorial: Advancement in Gene Set Analysis: Gaining Insight From High-Throughput Data.

18-06-2022

International journal of molecular sciences

Functional Screen for microRNAs Suppressing Anchorage-Independent Growth in Human Cervical Cancer Cells.

26-04-2022

Frontiers in immunology

Distinct Patterns of Myeloid Cell Infiltration in Patients With hrHPV-Positive and hrHPV-Negative Penile Squamous Cell Carcinoma: The Importance of Assessing Myeloid Cell Densities Within the Spatial Context of the Tumor.

02-07-2021

Cancer research

Delta-Like Ligand-Notch1 Signaling Is Selectively Modulated by HPV16 E6 to Promote Squamous Cell Proliferation and Correlates with Cervical Cancer Prognosis.

01-04-2021

eLife

Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells.

18-01-2021

Nature communications

A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities.

10-06-2020

Biosensors

Fecal Volatile Organic Compound Profiles are Not Influenced by Gestational Age and Mode of Delivery: A Longitudinal Multicenter Cohort Study.

11-05-2020

Molecular cancer therapeutics

Functional Genomic Screen in Mesothelioma Reveals that Loss of Function of BRCA1-Associated Protein 1 Induces Chemoresistance to Ribonucleotide Reductase Inhibition.

01-02-2020

Oncogene

High-throughput RNAi screening reveals cancer-selective lethal targets in the RNA spliceosome.

01-05-2019

Head & neck

HLA class II expression on tumor cells and low numbers of tumor-associated macrophages predict clinical outcome in oropharyngeal cancer.

01-02-2019

BMC Bioinformatics

Rscreenorm: normalization of CRISPR and siRNA screen data for more reproducible hit selection

20-08-2018

BMC bioinformatics

Rscreenorm: normalization of CRISPR and siRNA screen data for more reproducible hit selection.

20-08-2018

PLOS one

Improving stability of prediction models based on correlated omics data by using network approaches

20-02-2018

Scientific reports

A CDC42-centered signaling unit is a dominant positive regulator of endothelial integrity.

31-08-2017

Molecular oncology

A genome-wide siRNA screen for regulators of tumor suppressor p53 activity in human non-small cell lung cancer cells identifies components of the RNA splicing machinery as targets for anticancer treatment.

01-05-2017

BMC Bioinformatics

Analysing multiple types of molecular profiles simultaneously: connecting the needles in the haystack

09-02-2016

Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

23-01-2016

PloS one

Oncogenic Role of miR-15a-3p in 13q Amplicon-Driven Colorectal Adenoma-to-Carcinoma Progression.

07-07-2015

Radiation oncology (London, England)

A cell-based high-throughput screening assay for radiation susceptibility using automated cell counting.

27-02-2015

Stat Appl Genet Mol Biol.

General power and sample size calculations for high-dimensional genomic data

12-08-2013

Nucleic Acids Res.

Integrated analysis of microRNA and mRNA expression: adding biological significance to microRNA target predictions

14-06-2013

BMC Bioinformatics

Filtering, FDR and power

07-09-2010

Dual-modality breast cancer screening compared to MRI or mammography alone among female Hodgkin lymphoma survivors who received chest radiotherapy.

An accurate cellular assay to determine pathogenicity of coding and noncoding variants in Lynch syndrome genes.

Multiple Testing of Mix-and-Match Feature Sets in Multi-Omics.

Label-efficient computational tumour infiltrating lymphocyte assessment in breast cancer (ECTIL): multicentre validation in 2340 patients with breast cancer.

Health-related quality of life of patients with metastatic melanoma treated with tumor-infiltrating lymphocytes compared with ipilimumab in a randomized phase III trial.

Reanalysis of in vivo drug synergy validation study rules out synergy in most cases.

Epigenetic profiling identifies markers of endocrine resistance and therapeutic options for metastatic castration-resistant prostate cancer.

G6PC3 promotes genome maintenance and is a candidate mammary tumor suppressor.

The class II myosin MYH4 safeguards genome integrity and suppresses tumor progression.

Financial toxicity and socioeconomic impact of cancer in Europe.

A morphometric signature to identify ductal carcinoma in situ with a low risk of progression.

The oestrous cycle stage affects mammary tumour sensitivity to chemotherapy.

Artificial intelligence-assisted double reading of chest radiographs to detect clinically relevant missed findings: a two-centre evaluation.

Mechanisms that clear mutations drive field cancerization in mammary tissue.

Predictive gene expression profile for adjuvant taxane benefit in breast cancer in the MATADOR trial.

A new approach to describe the taxonomic structure of microbiome and its application to assess the relationship between microbial niches.

Artificial intelligence-based morphometric signature to identify ductal carcinoma in situ with low risk of progression to invasive breast cancer.

Locus-specific proteome decoding reveals Fpt1 as a chromatin-associated negative regulator of RNA polymerase III assembly.

Microbial Indicators of Dental Health, Dysbiosis, and Early Childhood Caries.

Taxanes trigger cancer cell killing in vivo by inducing non-canonical T cell cytotoxicity.

Artificial Intelligence Tool for Detection and Worklist Prioritization Reduces Time to Diagnosis of Incidental Pulmonary Embolism at CT.

ShrinkCRISPR: a flexible method for differential fitness analysis of CRISPR-Cas9 screen data.

Genome-wide siRNA screens identify RBBP9 function as a potential target in Fanconi anaemia-deficient head-and-neck squamous cell carcinoma.

A powerful global test for spliceQTL effects.

Electronic Nose Sensor Drift Affects Diagnostic Reliability and Accuracy of Disease-Specific Algorithms.

Editorial: Advancement in Gene Set Analysis: Gaining Insight From High-Throughput Data.

Functional Screen for microRNAs Suppressing Anchorage-Independent Growth in Human Cervical Cancer Cells.

Distinct Patterns of Myeloid Cell Infiltration in Patients With hrHPV-Positive and hrHPV-Negative Penile Squamous Cell Carcinoma: The Importance of Assessing Myeloid Cell Densities Within the Spatial Context of the Tumor.

Delta-Like Ligand-Notch1 Signaling Is Selectively Modulated by HPV16 E6 to Promote Squamous Cell Proliferation and Correlates with Cervical Cancer Prognosis.

Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells.

A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities.

Fecal Volatile Organic Compound Profiles are Not Influenced by Gestational Age and Mode of Delivery: A Longitudinal Multicenter Cohort Study.

Functional Genomic Screen in Mesothelioma Reveals that Loss of Function of BRCA1-Associated Protein 1 Induces Chemoresistance to Ribonucleotide Reductase Inhibition.

High-throughput RNAi screening reveals cancer-selective lethal targets in the RNA spliceosome.

HLA class II expression on tumor cells and low numbers of tumor-associated macrophages predict clinical outcome in oropharyngeal cancer.

Rscreenorm: normalization of CRISPR and siRNA screen data for more reproducible hit selection

Rscreenorm: normalization of CRISPR and siRNA screen data for more reproducible hit selection.

Improving stability of prediction models based on correlated omics data by using network approaches

A CDC42-centered signaling unit is a dominant positive regulator of endothelial integrity.

A genome-wide siRNA screen for regulators of tumor suppressor p53 activity in human non-small cell lung cancer cells identifies components of the RNA splicing machinery as targets for anticancer treatment.

Analysing multiple types of molecular profiles simultaneously: connecting the needles in the haystack

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Oncogenic Role of miR-15a-3p in 13q Amplicon-Driven Colorectal Adenoma-to-Carcinoma Progression.

A cell-based high-throughput screening assay for radiation susceptibility using automated cell counting.

General power and sample size calculations for high-dimensional genomic data

Integrated analysis of microRNA and mRNA expression: adding biological significance to microRNA target predictions

Filtering, FDR and power

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