Publications

Molecular oncology

MND1 enables homologous recombination in somatic cells primarily outside the context of replication.

01-07-2023

Science advances

FIRRM/C1orf112 mediates resolution of homologous recombination intermediates in response to DNA interstrand crosslinks.

02-06-2023

Cell reports

Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1- versus BRCA2-deficient mammary tumors.

30-05-2023

Nature communications

A doxycycline- and light-inducible Cre recombinase mouse model for optogenetic genome editing.

28-10-2022

STAR protocols

Protocol for live-cell imaging during Tumor Treating Fields treatment with Inovitro Live.

17-06-2022

Scientific reports

Dynamic FRET-FLIM based screening of signal transduction pathways.

20-10-2021

Current biology : CB

Retrofusion of intralumenal MVB membranes parallels viral infection and coexists with exosome release.

13-09-2021

Nature communications

Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer.

16-07-2021

Science (New York, N.Y.)

3D genomics across the tree of life reveals condensin II as a determinant of architecture type.

28-05-2021

NPJ breast cancer

Breast adipocyte size associates with ipsilateral invasive breast cancer risk after ductal carcinoma in situ.

22-03-2021

Cells

Resistance of Hypoxic Cells to Ionizing Radiation Is Mediated in Part via Hypoxia-Induced Quiescence.

10-03-2021

BMC biology

Sustained CHK2 activity, but not ATM activity, is critical to maintain a G1 arrest after DNA damage in untransformed cells.

19-02-2021

Nature protocols

Labeling and tracking of immune cells in ex vivo human skin.

01-02-2021

Nature immunology

Author Correction: Tissue patrol by resident memory CD8⁺ T cells in human skin.

01-06-2020

Nature medicine

Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers.

01-04-2020

Journal of cell science

Sequence-dependent trafficking and activity of GDE2, a GPI-specific phospholipase promoting neuronal differentiation.

10-02-2020

EMBO reports

PHF6 promotes non-homologous end joining and G2 checkpoint recovery.

07-01-2020

Nature immunology

Tissue patrol by resident memory CD8⁺ T cells in human skin.

01-06-2019

Molecular & cellular proteomics : MCP

Doxorubicin-induced DNA Damage Causes Extensive Ubiquitination of Ribosomal Proteins Associated with a Decrease in Protein Translation.

01-12-2018

Cancer cell

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.

11-06-2018

eLife

Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells.

29-08-2017

Nature communications

Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors.

13-07-2017

Nature communications

Hypersensitivity to DNA damage in antephase as a safeguard for genome stability.

26-08-2016

Biology open

PFA fixation enables artifact-free super-resolution imaging of the actin cytoskeleton and associated proteins.

15-07-2016

PloS one

Optimizing Imaging Conditions for Demanding Multi-Color Super Resolution Localization Microscopy.

09-07-2016

Nature methods

siFLIM: single-image frequency-domain FLIM provides fast and photon-efficient lifetime data.

01-06-2016

Nucleic acids research

The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80.

07-04-2016

Carcinogenesis

Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence.

01-11-2015

Journal of cell science

The molecular architecture of hemidesmosomes, as revealed with super-resolution microscopy.

15-10-2015

Nucleic acids research

The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80.

18-08-2015

Nature

REV7 counteracts DNA double-strand break resection and affects PARP inhibition.

28-05-2015

Cell cycle (Georgetown, Tex.)

Astral microtubules control redistribution of dynein at the cell cortex to facilitate spindle positioning.

21-02-2014

Current biology : CB

WAPL-mediated removal of cohesin protects against segregation errors and aneuploidy.

21-10-2013