Publications

Breast cancer research and treatment

Tamoxifen and pregnancy: an absolute contraindication?

Clinical pharmacokinetics

Impact of CYP3A4*22 on Pazopanib Pharmacokinetics in Cancer Patients.

Clinical pharmacokinetics

Population Pharmacokinetics of Fludarabine in Children and Adults during Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation.

Digestion

Does the 5-Aminosalicylate Concentration Correlate with the Efficacy of Oral 5-Aminosalicylate and Predict Response in Patients with Inflammatory Bowel Disease? A Systematic Review.

24-04-2019

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Innate Immune Recovery Predicts CD4⁺ T Cell Reconstitution after Hematopoietic Cell Transplantation.

Drugs & aging

Age-Associated Hematological Toxicity in Patients with Metastatic Castration-Resistant Prostate Cancer Treated with Docetaxel in Clinical Practice.

Journal of translational autoimmunity

Quantification of neutralizing anti-drug antibodies and their neutralizing capacity using competitive displacement and tandem mass spectrometry: Infliximab as proof of principle.

Cancer medicine

Neutropenia and docetaxel exposure in metastatic castration-resistant prostate cancer patients: A meta-analysis and evaluation of a clinical cohort.

Clinical genitourinary cancer

Plasma Levels of Enzalutamide and Its Main Metabolites in a Patient With Metastatic Castration-resistant Prostate Cancer Undergoing Hemodialysis.

Prostate cancer and prostatic diseases

Impact of age on exposure to oral antiandrogen therapies in clinical practice.

01-03-2019

Clinical pharmacokinetics

Therapeutic Drug Monitoring of Oral Anti-Hormonal Drugs in Oncology.

01-03-2019

PloS one

Pharmacokinetics of morphine in encephalopathic neonates treated with therapeutic hypothermia.

15-02-2019

Pharmaceutical research

Impact of Older Age on the Exposure of Paclitaxel: a Population Pharmacokinetic Study.

07-01-2019

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Validation and clinical application of an LC-MS/MS method for the quantification of everolimus using volumetric absorptive microsampling.

01-01-2019

Acta oncologica (Stockholm, Sweden)

Antineoplastic treatment with crizotinib during pregnancy: a case report.

01-01-2019

BMC cancer

Harnessing soft tissue sarcoma with low-dose pazopanib - a matter of blood levels.

03-12-2018

British journal of clinical pharmacology

Therapeutic drug monitoring of small molecule kinase inhibitors in oncology in a real-world cohort study: does age matter?

Investigational new drugs

Translational PK-PD modeling analysis of MCLA-128, a HER2/HER3 bispecific monoclonal antibody, to predict clinical efficacious exposure and dose.

Breast (Edinburgh, Scotland)

Therapeutic Drug Monitoring of endoxifen as an alternative for CYP2D6 genotyping in individualizing tamoxifen therapy.

British journal of clinical pharmacology

Food-effect study on uracil and dihydrouracil plasma levels as marker for dihydropyrimidine dehydrogenase activity in human volunteers.

Clinical pharmacokinetics

A Mechanism-Based Population Pharmacokinetic Analysis Assessing the Feasibility of Efavirenz Dose Reduction to 400 mg in Pregnant Women.

01-11-2018

Analytical and bioanalytical chemistry

Quantification of total dinutuximab concentrations in neuroblastoma patients with liquid chromatography tandem mass spectrometry.

01-09-2018

Journal of clinical pharmacy and therapeutics

Dosing oxaliplatin in a haemodialysis patient with metastatic rectum cancer monitored by free platinum concentrations.

01-08-2018

International journal of pharmaceutics

Solubility and bioavailability improvement of pazopanib hydrochloride.

10-06-2018

British journal of clinical pharmacology

Intracellular pharmacokinetics of gemcitabine, its deaminated metabolite 2',2'-difluorodeoxyuridine and their nucleotides.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Molecular Imaging of ABCB1 and ABCG2 Inhibition at the Human Blood-Brain Barrier Using Elacridar and ¹¹C-Erlotinib PET.

British journal of clinical pharmacology

Development of a nomogram for the estimation of long-term adherence to clozapine therapy using neutrophil fluorescence.

Journal of pharmacokinetics and pharmacodynamics

Pharmacodynamic modeling of cardiac biomarkers in breast cancer patients treated with anthracycline and trastuzumab regimens.