Publications

Nature medicine

High-throughput identification of antigen-specific TCRs by TCR gene capture.

01-11-2013

Acta oncologica (Stockholm, Sweden)

Ipilimumab in pretreated metastastic uveal melanoma patients. Results of the Dutch Working group on Immunotherapy of Oncology (WIN-O).

01-11-2013

Annals of oncology : official journal of the European Society for Medical Oncology

Efficacy and safety of ipilimumab in metastatic melanoma patients surviving more than 2 years following treatment in a phase III trial (MDX010-20).

01-10-2013

EJC supplements : EJC : official journal of EORTC, European Organization for Research and Treatment of Cancer ... [et al.]

Immunotherapy of melanoma.

01-09-2013

Vaccine

Transposon leads to contamination of clinical pDNA vaccine.

11-07-2013

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Vemurafenib as neoadjuvant treatment for unresectable regional metastatic melanoma.

01-06-2013

Cancer treatment reviews

Is combination therapy the next step to overcome resistance and reduce toxicities in melanoma?

01-06-2013

The Netherlands journal of medicine

Recent advances towards the clinical application of DNA vaccines.

01-04-2013

Human gene therapy

Rational design of DNA vaccines for the induction of human papillomavirus type 16 E6- and E7-specific cytotoxic T-cell responses.

01-12-2012

Proceedings of the National Academy of Sciences of the United States of America

Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen.

27-11-2012

Oncoimmunology

TIL therapy broadens the tumor-reactive CD8(+) T cell compartment in melanoma patients.

01-07-2012

Advances in immunology

Behavior and function of tissue-resident memory T cells.

28-03-2012

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Ipilimumab-induced sarcoidosis in a patient with metastatic melanoma undergoing complete remission.

10-01-2012

Lancet (London, England)

Tilting the AXIS towards therapeutic limits in renal cancer.

03-12-2011

Nederlands tijdschrift voor geneeskunde

[Issues around melanoma].

17-11-2011

Urology

A phase II study of presurgical sunitinib in patients with metastatic clear-cell renal carcinoma and the primary tumor in situ.

01-10-2011

Cancer immunology, immunotherapy : CII

Combination of targeted therapy and immunotherapy in melanoma.

01-10-2011

International journal of cancer

Preclinical development of highly effective and safe DNA vaccines directed against HPV 16 E6 and E7.

15-07-2011

Annals of oncology : official journal of the European Society for Medical Oncology

The safety and efficacy of sunitinib before planned nephrectomy in metastatic clear cell renal cancer.

01-05-2011

Clinical and experimental immunology

Lack of anti-tumour reactivity despite enhanced numbers of circulating natural killer T cells in two patients with metastatic renal cell carcinoma.

01-12-2010

Current topics in microbiology and immunology

DNA vaccines and intradermal vaccination by DNA tattooing.

26-11-2010

Human gene therapy

Microbead-assisted retroviral transduction for clinical application.

01-10-2010

Cancer immunology, immunotherapy : CII

RNA interference targeting programmed death receptor-1 improves immune functions of tumor-specific T cells.

01-08-2010

Current clinical pharmacology

DNA vaccination in oncology: current status, opportunities and perspectives.

01-08-2010

Annals of oncology : official journal of the European Society for Medical Oncology

Two-protein signature of novel serological markers apolipoprotein-A2 and serum amyloid alpha predicts prognosis in patients with metastatic renal cell cancer and improves the currently used prognostic survival models.

01-07-2010

International journal of pharmaceutics

Lipopolysaccharide contamination in intradermal DNA vaccination: toxic impurity or adjuvant?

05-05-2010

Nature medicine

Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy.

01-05-2010

AAPS PharmSciTech

Naked plasmid DNA formulation: effect of different disaccharides on stability after lyophilisation.

01-03-2010

Journal of controlled release : official journal of the Controlled Release Society

DNA tattoo vaccination: effect on plasmid purity and transfection efficiency of different topoisoforms.

15-10-2009

World journal of urology

Neoadjuvant sunitinib for surgically complex advanced renal cell cancer of doubtful resectability: initial experience with downsizing to reconsider cytoreductive surgery.

01-08-2009

Immunotherapy

Immunotherapeutic strategies: the melanoma example.

01-07-2009

Nature methods

Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers.

01-07-2009

Current opinion in immunology

Preclinical development of T cell receptor gene therapy.

01-04-2009

Journal of pharmaceutical and biomedical analysis

Development and validation of an anion-exchange LC-UV method for the quantification and purity determination of the DNA plasmid pDERMATT.

20-02-2009

Journal of immunology (Baltimore, Md. : 1950)

Requirements for effective antitumor responses of TCR transduced T cells.

01-10-2008

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

GMP production of pDERMATT for vaccination against melanoma in a phase I clinical trial.

01-10-2008

Anticancer research

Value of serum S-100B for prediction of distant relapse and survival in stage III B/C melanoma.

30-08-2008

Urologia internationalis

Cytokine therapy response as a selection criterion for cytoreductive nephrectomy in metastatic renal clear-cell carcinoma of intermediate prognosis. Results and conclusions from a combined analysis.

01-07-2008

Journal of immunology (Baltimore, Md. : 1950)

Long-term functionality of TCR-transduced T cells in vivo.

15-05-2008

Journal of immunology (Baltimore, Md. : 1950)

An inducible caspase 9 safety switch can halt cell therapy-induced autoimmune disease.

01-05-2008

Clinical cancer research : an official journal of the American Association for Cancer Research

Sunitinib for treatment of advanced renal cell cancer: primary tumor response.

15-04-2008

Cancer research

Skewing the T-cell repertoire by combined DNA vaccination, host conditioning, and adoptive transfer.

01-04-2008

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Brain metastases in patients with renal cell cancer receiving new targeted treatment.

01-01-2008

Blood

Selecting highly affine and well-expressed TCRs for gene therapy of melanoma.

15-11-2007

Journal of immunology (Baltimore, Md. : 1950)

In vivo antigen stability affects DNA vaccine immunogenicity.

15-08-2007

Journal of immunotherapy (Hagerstown, Md. : 1997)

Phase I clinical study with multiple peptide vaccines in combination with tetanus toxoid and GM-CSF in advanced-stage HLA-A*0201-positive melanoma patients.

02-05-2007

Laboratory investigation; a journal of technical methods and pathology

Validation of SELDI-TOF MS serum protein profiles for renal cell carcinoma in new populations.

01-02-2007

BMC biotechnology

Intravital imaging of fluorescent markers and FRET probes by DNA tattooing.

03-01-2007

Blood

Targeting self-antigens through allogeneic TCR gene transfer.

01-08-2006

Journal of immunology (Baltimore, Md. : 1950)

Immunological and antitumor effects of IL-23 as a cancer vaccine adjuvant.

01-05-2006