Publications

Cancers

Systemic Therapy in Advanced Nodular Melanoma versus Superficial Spreading Melanoma: A Nation-Wide Study of the Dutch Melanoma Treatment Registry.

19-11-2022

European journal of cancer (Oxford, England : 1990)

Characteristics of immune checkpoint inhibitor-induced encephalitis and comparison with HSV-1 and anti-LGI1 encephalitis: A retrospective multicentre cohort study.

01-11-2022

Nature medicine

Diet-driven microbial ecology underpins associations between cancer immunotherapy outcomes and the gut microbiome.

01-11-2022

European journal of cancer (Oxford, England : 1990)

Real-world outcomes with ipilimumab and nivolumab in advanced melanoma: a multicentre retrospective study.

01-11-2022

NEJM evidence

Five-Year Analysis of Adjuvant Pembrolizumab or Placebo in Stage III Melanoma.

01-11-2022

JCO oncology practice

End-of-Life Use of Systemic Therapy in Patients With Advanced Melanoma: A Nationwide Cohort Study.

01-10-2022

Journal of translational medicine

Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd - 4th, 2021, Italy).

04-09-2022

JCO precision oncology

BRAF and NRAS Mutation Status and Response to Checkpoint Inhibition in Advanced Melanoma.

01-09-2022

Annals of oncology : official journal of the European Society for Medical Oncology

Single-agent anti-PD-1 or combined with ipilimumab in patients with mucosal melanoma: an international, retrospective, cohort study.

01-09-2022

Immuno-oncology technology

MART-1 TCR gene-modified peripheral blood T cells for the treatment of metastatic melanoma: a phase I/IIa clinical trial.

01-09-2022

Clinica chimica acta; international journal of clinical chemistry

Diagnostic performance of early increase in S100B or LDH as outcome predictor for non-responsiveness to anti-PD-1 monotherapy in advanced melanoma.

01-08-2022

Annals of surgical oncology

Correction to: Neoadjuvant Systemic Therapy (NAST) in Patients with Melanoma: Surgical Considerations by the International Neoadjuvant Melanoma Consortium (INMC).

01-08-2022

BJU international

Cytoreductive nephrectomy and exposure to sunitinib - a post hoc analysis of the Immediate Surgery or Surgery After Sunitinib Malate in Treating Patients With Metastatic Kidney Cancer (SURTIME) trial.

01-07-2022

Journal for immunotherapy of cancer

Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma.

01-07-2022

Journal for immunotherapy of cancer

Dendritic cell-mediated cross presentation of tumor-derived peptides is biased against plasma membrane proteins.

01-07-2022

Annals of surgical oncology

Neoadjuvant Systemic Therapy (NAST) in Patients with Melanoma: Surgical Considerations by the International Neoadjuvant Melanoma Consortium (INMC).

01-06-2022

Nature medicine

Personalized response-directed surgery and adjuvant therapy after neoadjuvant ipilimumab and nivolumab in high-risk stage III melanoma: the PRADO trial.

01-06-2022

Journal of translational medicine

The "Great Debate" at Melanoma Bridge 2021, December 2nd-4th, 2021.

10-05-2022

European journal of cancer (Oxford, England : 1990)

Response to immune checkpoint inhibitors in acral melanoma: A nationwide cohort study.

01-05-2022

British journal of cancer

Correction: First-line BRAF/MEK inhibitors versus anti-PD-1 monotherapy in BRAF^V600-mutant advanced melanoma patients: a propensity-matched survival analysis.

01-05-2022

Science translational medicine

Addition of interleukin-2 overcomes resistance to neoadjuvant CTLA4 and PD1 blockade in ex vivo patient tumors.

27-04-2022

European journal of cancer (Oxford, England : 1990)

Prognostic and predictive value of β-blockers in the EORTC 1325/KEYNOTE-054 phase III trial of pembrolizumab versus placebo in resected high-risk stage III melanoma.

01-04-2022

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Clinical Models to Define Response and Survival With Anti-PD-1 Antibodies Alone or Combined With Ipilimumab in Metastatic Melanoma.

01-04-2022

JAMA surgery

Representativeness of the Index Lymph Node for Total Nodal Basin in Pathologic Response Assessment After Neoadjuvant Checkpoint Inhibitor Therapy in Patients With Stage III Melanoma.

01-04-2022

International journal of cancer

The unfavorable effects of COVID-19 on Dutch advanced melanoma care.

01-03-2022

Trials

Combining Hepatic Percutaneous Perfusion with Ipilimumab plus Nivolumab in advanced uveal melanoma (CHOPIN): study protocol for a phase Ib/randomized phase II trial.

13-02-2022

European journal of cancer (Oxford, England : 1990)

Chemotherapy after immune checkpoint inhibitor failure in metastatic melanoma: a retrospective multicentre analysis.

01-02-2022

Journal of the European Academy of Dermatology and Venereology : JEADV

Survival of stage IV melanoma in Belgium and the Netherlands.

01-02-2022

Annals of oncology : official journal of the European Society for Medical Oncology

Antitumor activity of ipilimumab or BRAF ± MEK inhibition after pembrolizumab treatment in patients with advanced melanoma: analysis from KEYNOTE-006.

01-02-2022

Cancer cell

Multiomic profiling of checkpoint inhibitor-treated melanoma: Identifying predictors of response and resistance, and markers of biological discordance.

10-01-2022

European urology open science

Primary Renal Tumour Response in Patients Treated with Nivolumab and Ipilimumab for Metastatic Renal Cell Carcinoma: Real-world Data Assessment.

01-01-2022

Nature communications

Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma.

22-12-2021

Current oncology (Toronto, Ont.)

Phase Ib Study of Atezolizumab Plus Interferon-α with or without Bevacizumab in Patients with Metastatic Renal Cell Carcinoma and Other Solid Tumors.

20-12-2021

The Lancet. Oncology

mRNA-1273 COVID-19 vaccination in patients receiving chemotherapy, immunotherapy, or chemoimmunotherapy for solid tumours: a prospective, multicentre, non-inferiority trial.

01-12-2021

European journal of cancer (Oxford, England : 1990)

Adjuvant treatment for melanoma in clinical practice - Trial versus reality.

01-11-2021

Proceedings of the National Academy of Sciences of the United States of America

Differential effects of PD-1 and CTLA-4 blockade on the melanoma-reactive CD8 T cell response.

26-10-2021

European journal of cancer (Oxford, England : 1990)

Crossover and rechallenge with pembrolizumab in recurrent patients from the EORTC 1325-MG/Keynote-054 phase III trial, pembrolizumab versus placebo after complete resection of high-risk stage III melanoma.

18-10-2021

Cancers

Hospital Variation in Cancer Treatments and Survival OutComes of Advanced Melanoma Patients: Nationwide Quality Assurance in The Netherlands.

11-10-2021

Clinical cancer research : an official journal of the American Association for Cancer Research

Predictive Immune-Checkpoint Blockade Classifiers Identify Tumors Responding to Inhibition of PD-1 and/or CTLA-4.

01-10-2021

Cancer immunology, immunotherapy : CII

Metabolic profiles of regulatory T cells in the tumour microenvironment.

01-09-2021

Annals of surgery

Neoadjuvant Cytoreductive Treatment With BRAF/MEK Inhibition of Prior Unresectable Regionally Advanced Melanoma to Allow Complete Surgical Resection, REDUCTOR: A Prospective, Single-arm, Open-label Phase II Trial.

01-08-2021

The American Journal of dermatopathology

Letter Regarding Editorial by Samuel Zagarella.

01-07-2021

European journal of cancer (Oxford, England : 1990)

Neoadjuvant immunotherapy is reshaping cancer management across multiple tumour types: The future is now!

01-07-2021

Annals of oncology : official journal of the European Society for Medical Oncology

Delayed immune-related adverse events with anti-PD-1-based immunotherapy in melanoma.

01-07-2021

European journal of cancer (Oxford, England : 1990)

The role of local therapy in the treatment of solitary melanoma progression on immune checkpoint inhibition: A multicentre retrospective analysis.

01-07-2021

Nature medicine

An ex vivo tumor fragment platform to dissect response to PD-1 blockade in cancer.

01-07-2021

Journal of translational medicine

Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 3rd-5th, 2020, Italy).

30-06-2021

Cancers

Toxicity, Response and Survival in Older Patients with Metastatic Melanoma Treated with Checkpoint Inhibitors.

05-06-2021

The Lancet. Oncology

Ipilimumab alone or ipilimumab plus anti-PD-1 therapy in patients with metastatic melanoma resistant to anti-PD-(L)1 monotherapy: a multicentre, retrospective, cohort study.

01-06-2021

Annals of oncology : official journal of the European Society for Medical Oncology

Pathological response and tumour bed histopathological features correlate with survival following neoadjuvant immunotherapy in stage III melanoma.

01-06-2021