Publications

Epigenetics

Evaluation of methylated DCR1 as a biomarker for response to adjuvant irinotecan-based therapy in stage III colon cancer: cancer and leukaemia Group B 89803 (Alliance).

01-12-2022

World journal of gastrointestinal oncology

Missed colorectal cancers in a fecal immunochemical test-based screening program: Molecular profiling of interval carcinomas.

15-11-2022

Clinical cancer research : an official journal of the American Association for Cancer Research

PD-1T TILs as a Predictive Biomarker for Clinical Benefit to PD-1 Blockade in Patients with Advanced NSCLC.

14-11-2022

British journal of cancer

Somatic hits in mismatch repair genes in colorectal cancer among non-seminoma testicular cancer survivors.

01-11-2022

Preventive medicine

Guidance for setting international standards on reporting longitudinal adherence to stool-based colorectal cancer screening.

01-11-2022

The Journal of pathology

Feasibility of whole-genome sequencing-based tumor diagnostics in routine pathology practice.

01-10-2022

Annals of internal medicine

Adenoma Detection Rate and Risk for Interval Postcolonoscopy Colorectal Cancer in Fecal Immunochemical Test-Based Screening : A Population-Based Cohort Study.

01-10-2022

Neoplasia (New York, N.Y.)

Overexpression of the miR-17-92 cluster in colorectal adenoma organoids causes a carcinoma-like gene expression signature.

01-10-2022

Inflammatory bowel diseases

Genetic Profiling of Colorectal Carcinomas of Patients with Primary Sclerosing Cholangitis and Inflammatory Bowel Disease.

01-09-2022

PloS one

Molecular characterization of gastric adenocarcinoma diagnosed in patients previously treated for Hodgkin lymphoma or testicular cancer.

26-07-2022

Scientific reports

High expression of secretory leukocyte protease inhibitor (SLPI) in stage III micro-satellite stable colorectal cancer is associated with reduced disease recurrence.

16-07-2022

The Journal of pathology

The earliest events in BRAF-mutant colorectal cancer: exome sequencing of sessile serrated lesions with a tiny focus dysplasia or cancer reveals recurring mutations in two distinct progression pathways.

01-06-2022

Clinical and translational gastroenterology

Lessons From a Systematic Literature Search on Diagnostic DNA Methylation Biomarkers for Colorectal Cancer: How to Increase Research Value and Decrease Research Waste?

01-06-2022

BMC cancer

KCNQ1 and lymphovascular invasion are key features in a prognostic classifier for stage II and III colon cancer.

08-04-2022

British journal of cancer

Molecular pathways in post-colonoscopy versus detected colorectal cancers: results from a nested case-control study.

01-04-2022

JCO precision oncology

Reply to R. Pham et al.

01-03-2022

JCO clinical cancer informatics

Genome Nexus: A Comprehensive Resource for the Annotation and Interpretation of Genomic Variants in Cancer.

01-02-2022

Cancers

Clinical Impact of Prospective Whole Genome Sequencing in Sarcoma Patients.

16-01-2022

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society

Clinicopathological features and risk factors for developing colorectal neoplasia in Hodgkin's lymphoma survivors.

01-01-2022

GigaScience

Fusion transcripts and their genomic breakpoints in polyadenylated and ribosomal RNA-minus RNA sequencing data.

09-12-2021

JCO precision oncology

KRAS A146 Mutations Are Associated With Distinct Clinical Behavior in Patients With Colorectal Liver Metastases.

26-11-2021

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Planning target volume margin assessment for online adaptive MR-guided dose-escalation in rectal cancer on a 1.5 T MR-Linac.

01-09-2021

Annals of internal medicine

Clinical Validation of a Multitarget Fecal Immunochemical Test for Colorectal Cancer Screening : A Diagnostic Test Accuracy Study.

01-09-2021

Nature communications

Detection and characterization of lung cancer using cell-free DNA fragmentomes.

20-08-2021

Histopathology

High CD8⁺ tumour-infiltrating lymphocyte density associates with unfavourable prognosis in oesophageal adenocarcinoma following poor response to neoadjuvant chemoradiotherapy.

01-08-2021

EBioMedicine

Postoperative circulating tumour DNA is associated with pathologic response and recurrence-free survival after resection of colorectal cancer liver metastases.

01-08-2021

Clinical chemistry

An Automated Correction Algorithm (ALPACA) for ddPCR Data Using Adaptive Limit of Blank and Correction of False Positive Events Improves Specificity of Mutation Detection.

06-07-2021

The journal of pathology. Clinical research

Detection of tumor-derived cell-free DNA from colorectal cancer peritoneal metastases in plasma and peritoneal fluid.

01-05-2021

Clinical epigenetics

Identification of DNA methylation markers for early detection of CRC indicates a role for nervous system-related genes in CRC.

15-04-2021

Histopathology

RNF43 mutation analysis in serrated polyposis, sporadic serrated polyps and Lynch syndrome polyps.

01-04-2021

Histopathology

Driver mutations occur frequently in metastases of well-differentiated small intestine neuroendocrine tumours.

01-03-2021

BMC gastroenterology

Diagnostic yield of colonoscopy surveillance in testicular cancer survivors treated with platinum-based chemotherapy: study protocol of a prospective cross-sectional cohort study.

12-02-2021

European journal of cancer (Oxford, England : 1990)

Quantitative analysis of CDX2 protein expression improves its clinical utility as a prognostic biomarker in stage II and III colon cancer.

01-02-2021

PloS one

Gene expression profiles of esophageal squamous cell cancers in Hodgkin lymphoma survivors versus sporadic cases.

22-12-2020

The Journal of molecular diagnostics : JMD

Diagnostic Strategies toward Clinical Implementation of Liquid Biopsy RAS/BRAF Circulating Tumor DNA Analyses in Patients with Metastatic Colorectal Cancer.

01-12-2020

BMC medical genomics

Study protocol: Whole genome sequencing Implementation in standard Diagnostics for Every cancer patient (WIDE).

10-11-2020

Oncoimmunology

Expression of the immune modulator secretory leukocyte protease inhibitor (SLPI) in colorectal cancer liver metastases and matched primary tumors is associated with a poorer prognosis.

13-10-2020

The European journal of health economics : HEPAC : health economics in prevention and care

Modeling Personalized Adjuvant TreaTment in EaRly stage coloN cancer (PATTERN).

01-09-2020

BMC cancer

Circulating tumor DNA guided adjuvant chemotherapy in stage II colon cancer (MEDOCC-CrEATE): study protocol for a trial within a cohort study.

20-08-2020

Journal of comparative effectiveness research

Can a biomarker triage test reduce colonoscopy burden in fecal immunochemical test screening?

01-06-2020

Scientific reports

Performance of four platforms for KRAS mutation detection in plasma cell-free DNA: ddPCR, Idylla, COBAS z480 and BEAMing.

15-05-2020

International journal of cancer

Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression.

01-04-2020

International journal of radiation oncology, biology, physics

Preoperative Prediction of Pathologic Response to Neoadjuvant Chemoradiotherapy in Patients With Esophageal Cancer Using ¹⁸F-FDG PET/CT and DW-MRI: A Prospective Multicenter Study.

01-04-2020

The Journal of pathology

Proteins in stool as biomarkers for non-invasive detection of colorectal adenomas with high risk of progression.

01-03-2020

Nature communications

White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer.

27-01-2020

Journal of clinical medicine

Diagnostic Accuracy of Stool Tests for Colorectal Cancer Surveillance in Hodgkin Lymphoma Survivors.

10-01-2020

Inflammatory bowel diseases

IBD-Associated Dysplastic Lesions Show More Chromosomal Instability Than Sporadic Adenomas.

06-01-2020

The American journal of gastroenterology

Multitarget Stool DNA Test Performance in an Average-Risk Colorectal Cancer Screening Population.

01-12-2019

Advances in radiation oncology

Gross Tumor Delineation in Esophageal Cancer on MRI Compared With ¹⁸F-FDG-PET/CT.

02-11-2019

Molecular aspects of medicine

The landscape of genomic copy number alterations in colorectal cancer and their consequences on gene expression levels and disease outcome.

01-10-2019

Evaluation of methylated DCR1 as a biomarker for response to adjuvant irinotecan-based therapy in stage III colon cancer: cancer and leukaemia Group B 89803 (Alliance).

Missed colorectal cancers in a fecal immunochemical test-based screening program: Molecular profiling of interval carcinomas.

PD-1T TILs as a Predictive Biomarker for Clinical Benefit to PD-1 Blockade in Patients with Advanced NSCLC.

Somatic hits in mismatch repair genes in colorectal cancer among non-seminoma testicular cancer survivors.

Guidance for setting international standards on reporting longitudinal adherence to stool-based colorectal cancer screening.

Feasibility of whole-genome sequencing-based tumor diagnostics in routine pathology practice.

Adenoma Detection Rate and Risk for Interval Postcolonoscopy Colorectal Cancer in Fecal Immunochemical Test-Based Screening : A Population-Based Cohort Study.

Overexpression of the miR-17-92 cluster in colorectal adenoma organoids causes a carcinoma-like gene expression signature.

Genetic Profiling of Colorectal Carcinomas of Patients with Primary Sclerosing Cholangitis and Inflammatory Bowel Disease.

Molecular characterization of gastric adenocarcinoma diagnosed in patients previously treated for Hodgkin lymphoma or testicular cancer.

High expression of secretory leukocyte protease inhibitor (SLPI) in stage III micro-satellite stable colorectal cancer is associated with reduced disease recurrence.

The earliest events in BRAF-mutant colorectal cancer: exome sequencing of sessile serrated lesions with a tiny focus dysplasia or cancer reveals recurring mutations in two distinct progression pathways.

Lessons From a Systematic Literature Search on Diagnostic DNA Methylation Biomarkers for Colorectal Cancer: How to Increase Research Value and Decrease Research Waste?

KCNQ1 and lymphovascular invasion are key features in a prognostic classifier for stage II and III colon cancer.

Molecular pathways in post-colonoscopy versus detected colorectal cancers: results from a nested case-control study.

Reply to R. Pham et al.

Genome Nexus: A Comprehensive Resource for the Annotation and Interpretation of Genomic Variants in Cancer.

Clinical Impact of Prospective Whole Genome Sequencing in Sarcoma Patients.

Clinicopathological features and risk factors for developing colorectal neoplasia in Hodgkin's lymphoma survivors.

Fusion transcripts and their genomic breakpoints in polyadenylated and ribosomal RNA-minus RNA sequencing data.

KRAS A146 Mutations Are Associated With Distinct Clinical Behavior in Patients With Colorectal Liver Metastases.

Planning target volume margin assessment for online adaptive MR-guided dose-escalation in rectal cancer on a 1.5 T MR-Linac.

Clinical Validation of a Multitarget Fecal Immunochemical Test for Colorectal Cancer Screening : A Diagnostic Test Accuracy Study.

Detection and characterization of lung cancer using cell-free DNA fragmentomes.

High CD8+ tumour-infiltrating lymphocyte density associates with unfavourable prognosis in oesophageal adenocarcinoma following poor response to neoadjuvant chemoradiotherapy.

Postoperative circulating tumour DNA is associated with pathologic response and recurrence-free survival after resection of colorectal cancer liver metastases.

An Automated Correction Algorithm (ALPACA) for ddPCR Data Using Adaptive Limit of Blank and Correction of False Positive Events Improves Specificity of Mutation Detection.

Detection of tumor-derived cell-free DNA from colorectal cancer peritoneal metastases in plasma and peritoneal fluid.

Identification of DNA methylation markers for early detection of CRC indicates a role for nervous system-related genes in CRC.

RNF43 mutation analysis in serrated polyposis, sporadic serrated polyps and Lynch syndrome polyps.

Driver mutations occur frequently in metastases of well-differentiated small intestine neuroendocrine tumours.

Diagnostic yield of colonoscopy surveillance in testicular cancer survivors treated with platinum-based chemotherapy: study protocol of a prospective cross-sectional cohort study.

Quantitative analysis of CDX2 protein expression improves its clinical utility as a prognostic biomarker in stage II and III colon cancer.

Gene expression profiles of esophageal squamous cell cancers in Hodgkin lymphoma survivors versus sporadic cases.

Diagnostic Strategies toward Clinical Implementation of Liquid Biopsy RAS/BRAF Circulating Tumor DNA Analyses in Patients with Metastatic Colorectal Cancer.

Study protocol: Whole genome sequencing Implementation in standard Diagnostics for Every cancer patient (WIDE).

Expression of the immune modulator secretory leukocyte protease inhibitor (SLPI) in colorectal cancer liver metastases and matched primary tumors is associated with a poorer prognosis.

Modeling Personalized Adjuvant TreaTment in EaRly stage coloN cancer (PATTERN).

Circulating tumor DNA guided adjuvant chemotherapy in stage II colon cancer (MEDOCC-CrEATE): study protocol for a trial within a cohort study.

Can a biomarker triage test reduce colonoscopy burden in fecal immunochemical test screening?

Performance of four platforms for KRAS mutation detection in plasma cell-free DNA: ddPCR, Idylla, COBAS z480 and BEAMing.

Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression.

Preoperative Prediction of Pathologic Response to Neoadjuvant Chemoradiotherapy in Patients With Esophageal Cancer Using 18F-FDG PET/CT and DW-MRI: A Prospective Multicenter Study.

Proteins in stool as biomarkers for non-invasive detection of colorectal adenomas with high risk of progression.

White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer.

Diagnostic Accuracy of Stool Tests for Colorectal Cancer Surveillance in Hodgkin Lymphoma Survivors.

IBD-Associated Dysplastic Lesions Show More Chromosomal Instability Than Sporadic Adenomas.

Multitarget Stool DNA Test Performance in an Average-Risk Colorectal Cancer Screening Population.

Gross Tumor Delineation in Esophageal Cancer on MRI Compared With 18F-FDG-PET/CT.

The landscape of genomic copy number alterations in colorectal cancer and their consequences on gene expression levels and disease outcome.

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High CD8⁺ tumour-infiltrating lymphocyte density associates with unfavourable prognosis in oesophageal adenocarcinoma following poor response to neoadjuvant chemoradiotherapy.

Preoperative Prediction of Pathologic Response to Neoadjuvant Chemoradiotherapy in Patients With Esophageal Cancer Using ¹⁸F-FDG PET/CT and DW-MRI: A Prospective Multicenter Study.

Gross Tumor Delineation in Esophageal Cancer on MRI Compared With ¹⁸F-FDG-PET/CT.