Publications

Nature communications

USP1/UAF1 targets polyubiquitinated PCNA with an exo-cleavage mechanism that can temporarily enrich for monoubiquitinated PCNA.

30-07-2025

The Journal of biological chemistry

Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site.

25-09-2020

Biochemistry and biophysics reports

Biochemical characterization of TRIM72 E3 ligase and its interaction with the insulin receptor substrate 1.

01-03-2020

Methods in enzymology

Quantitative analysis of USP activity in vitro.

10-03-2019

Nature

Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage.

19-11-2015

Trends in biochemical sciences

Layers of DUB regulation.

01-08-2015

Molecular cell

Make them, break them, and catch them: studying rare ubiquitin chains.

02-04-2015

Cell

RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling.

14-09-2012

Biochemical Society transactions

The role of UBL domains in ubiquitin-specific proteases.

01-06-2012

Journal of medicinal chemistry

Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis.

23-04-2009

The EMBO journal

Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b.

07-06-2006

The Journal of biological chemistry

Crystal structure of acetylcholine-binding protein from Bulinus truncatus reveals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors.

15-07-2005

Annual review of biophysics and biomolecular structure

Acetylcholine binding protein (AChBP): a secreted glial protein that provides a high-resolution model for the extracellular domain of pentameric ligand-gated ion channels.

16-04-2003