Publications

EMBO reports

Transcription elongation can be sufficient, but is not necessary, to advance replication timing.

Nature

Regulatory grammar in human promoters uncovered by MPRA-based deep learning.

Nature

An integrated view of the structure and function of the human 4D nucleome.

Nature structural & molecular biology

Interactions between the genome and the nuclear lamina are multivalent and cooperative.

Nature reviews. Genetics

Predicting gene expression from DNA sequence using deep learning models.

Nucleic acids research

Coordinated control of genome-nuclear lamina interactions by topoisomerase 2B and lamin B receptor.

Functional maps of a genomic locus reveal confinement of an enhancer by its target gene

Science (New York, N.Y.)

Functional maps of a genomic locus reveal confinement of an enhancer by its target gene.

Nucleic acids research

Extrusion fountains are restricted by WAPL-dependent cohesin release and CTCF barriers.

Nature biotechnology

Machine learning prediction of prime editing efficiency across diverse chromatin contexts.

eLife

Major nuclear locales define nuclear genome organization and function beyond A and B compartments.

Cell systems

Optimized reporters for multiplexed detection of transcription factor activity.

eLife

Large-scale analysis of the integration of enhancer-enhancer signals by promoters.

bioRxiv : the preprint server for biology

An integrated view of the structure and function of the human 4D nucleome.

Communications biology

Nucleolus and centromere Tyramide Signal Amplification-Seq reveals variable localization of heterochromatin in different cell types.

Nucleic acids research

Chromatin context-dependent effects of epigenetic drugs on CRISPR-Cas9 editing.

bioRxiv : the preprint server for biology

Optimized reporters for multiplexed detection of transcription factor activity.

The regulatory grammar of human promoters uncovered by MPRA-trained deep learning

Cell reports

Perturbations in 3D genome organization can promote acquired drug resistance.

Nucleic acids research

Optimisation of TP53 reporters by systematic dissection of synthetic TP53 response elements.

Nature

Heritable transcriptional defects from aberrations of nuclear architecture.

EMBO reports

Dynamic chromosomal interactions and control of heterochromatin positioning by Ki-67.

Genome biology

CTCF and cohesin promote focal detachment of DNA from the nuclear lamina.

Molecular cell

Systematic analysis of intrinsic enhancer-promoter compatibility in the mouse genome.

Nature

Nonlinear control of transcription through enhancer-promoter interactions.

Methods in molecular biology (Clifton, N.J.)

Genome-Wide Mapping and Microscopy Visualization of Protein-DNA Interactions by pA-DamID.

Current opinion in cell biology

Lamina-associated domains: Tethers and looseners.

Molecular cell

Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance.

Open biology

m6A methylation potentiates cytosolic dsDNA recognition in a sequence-specific manner.

EMBO reports

Cell cycle dynamics of lamina-associated DNA.

Developmental cell

Phosphorylated Lamins in Euchromatin: New Clues to Progeria.

The EMBO journal

Local rewiring of genome-nuclear lamina interactions by transcription.

Nature genetics

High-throughput identification of human SNPs affecting regulatory element activity.

Nature reviews. Molecular cell biology

The role of transcription in shaping the spatial organization of the genome.

Methods in molecular biology (Clifton, N.J.)

Rapid Quantitative Evaluation of CRISPR Genome Editing by TIDE and TIDER.

Epigenetics & chromatin

The large fraction of heterochromatin in Drosophila neurons is bound by both B-type lamin and HP1a.

Epigenetics & chromatin

Correction to: DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis.

Molecular cell

Kinetics and Fidelity of the Repair of Cas9-Induced Double-Strand DNA Breaks.

Epigenetics & chromatin

DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis.

Nucleic acids research

Easy quantification of template-directed CRISPR/Cas9 editing.

Life science alliance

CHRAC/ACF contribute to the repressive ground state of chromatin.

Genome research

Massive reshaping of genome-nuclear lamina interactions during oncogene-induced senescence.

PLoS genetics

Comprehensive analysis of nucleocytoplasmic dynamics of mRNA in Drosophila cells.

Genome research

Clustering of Drosophila housekeeping promoters facilitates their expression.

Genome research

Small chromosomal regions position themselves autonomously according to their chromatin class.

Cell

Lamina-Associated Domains: Links with Chromosome Architecture, Heterochromatin, and Gene Repression.

Current opinion in genetics & development

Genome-nuclear lamina interactions: from cell populations to single cells.

Nature biotechnology

Genome-wide mapping of autonomous promoter activity in human cells.

Epigenetics & chromatin

High-throughput assessment of context-dependent effects of chromatin proteins.

Genes & development

A single double-strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatin.