Publications

British journal of cancer

Combination of EZH2 and ATM inhibition in BAP1-deficient mesothelioma.

01-05-2024

Cancer gene therapy

Retinoids and EZH2 inhibitors cooperate to orchestrate anti-oncogenic effects on bladder cancer cells.

01-04-2024

Cancer research communications

Combined Inhibition of EZH2 and FGFR is Synergistic in BAP1-deficient Malignant Mesothelioma.

03-01-2024

Breast cancer research : BCR

Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer.

17-06-2022

Cell reports

USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells.

29-12-2020

PloS one

A genome-wide enrichment screen identifies NUMA1-loss as a resistance mechanism against mitotic cell-death induced by BMI1 inhibition.

29-04-2020

Clinical cancer research : an official journal of the American Association for Cancer Research

EZH2 Is Overexpressed in BRCA1-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy.

15-07-2019

Gastroenterology

Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells.

01-10-2016

Cell reports

Prolonged Ezh2 Depletion in Glioblastoma Causes a Robust Switch in Cell Fate Resulting in Tumor Progression.

20-01-2015

Cell

Chromatin position effects assayed by thousands of reporters integrated in parallel.

15-08-2013

PloS one

Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors.

22-05-2013

Methods (San Diego, Calif.)

Chromosome conformation capture on chip in single Drosophila melanogaster tissues.

01-11-2012

Development (Cambridge, England)

The Polycomb group protein Ring1b is essential for pectoral fin development.

01-06-2012

PloS one

GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors.

11-05-2012

Proceedings of the National Academy of Sciences of the United States of America

The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish.

15-03-2011

Cancer research

Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypes.

15-01-2010

Breast cancer research : BCR

BRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A.

28-08-2009

Biochimica et biophysica acta

Bmi1 deficient neural stem cells have increased integrin dependent adhesion to self-secreted matrix.

01-05-2009

Oncogene

In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation.

20-11-2008

Cell division

The many faces of ubiquitinated histone H2A: insights from the DUBs.

22-04-2008

The EMBO journal

Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b.

07-06-2006

Cell cycle (Georgetown, Tex.)

Controlling stem cell proliferation: CKIs at work.

01-06-2006

Oncogene

Retroviral insertional mutagenesis: past, present and future.

21-11-2005

Cancer cell

RUNX: a trilogy of cancer genes.

01-04-2002

Journal of cell science

Chromatin-association of the Polycomb group protein BMI1 is cell cycle-regulated and correlates with its phosphorylation status.

01-12-1999

Current opinion in genetics & development

The trithorax-group and polycomb-group chromatin modifiers: implications for disease.

01-06-1999

Cell

Predisposition to lymphomagenesis in pim-1 transgenic mice: cooperation with c-myc and N-myc in murine leukemia virus-induced tumors.

24-02-1989

International journal of cancer. Supplement = Journal international du cancer. Supplement

Transgenic mice as a means to study synergism between oncogenes.

01-01-1989