Publications

Epigenetics

Evaluation of methylated DCR1 as a biomarker for response to adjuvant irinotecan-based therapy in stage III colon cancer: cancer and leukaemia Group B 89803 (Alliance).

01-12-2022

Clinical pharmacokinetics

Pharmacokinetics and Pharmacodynamics of PARP Inhibitors in Oncology.

01-12-2022

NeuroImage

A unified model for reconstruction and R₂^* mapping of accelerated 7T data using the quantitative recurrent inference machine.

01-12-2022

International journal of cancer

Reply to: Comments on "Effect of HIPEC according to HRD/BRCAwt genomic profile in stage III ovarian cancer: Results from the phase III OVHIPEC trial".

01-12-2022

Melanoma research

Long-term survival of patients with advanced melanoma treated with BRAF-MEK inhibitors.

01-12-2022

European journal of cancer (Oxford, England : 1990)

Tumour break load is a biologically relevant feature of genomic instability with prognostic value in colorectal cancer.

01-12-2022

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Results of a worldwide survey on the currently used histopathological diagnostic criteria for invasive lobular breast cancer.

01-12-2022

Data in brief

Dataset of a retrospective multicenter cohort study on characteristics of immune checkpoint inhibitor-induced encephalitis and comparison with HSV-1 and anti-LGI1 encephalitis.

01-12-2022

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Dose response modelling of secretory cell loss in salivary glands using PSMA PET.

01-12-2022

Journal of medical genetics

Enhancing the BOADICEA cancer risk prediction model to incorporate new data on RAD51C, RAD51D, BARD1 updates to tumour pathology and cancer incidence.

01-12-2022

Nature reviews. Cancer

Learning to distinguish progressive and non-progressive ductal carcinoma in situ.

01-12-2022

Archives of physical medicine and rehabilitation

Construct Validity of the Steep Ramp Test for Assessing Cardiorespiratory Fitness in Patients With Breast Cancer and the Effect of Chemotherapy-Related Symptom Burden.

01-12-2022

Critical reviews in oncology/hematology

Cancer-related cognitive impairment in non-CNS cancer patients: Targeted review and future action plans in Europe.

01-12-2022

ESMO open

Sex differences in patients with gastrointestinal stromal tumours: do they exist and does it affect survival?

01-12-2022

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Quality of early prostate cancer follow-up care from the patients' perspective.

01-12-2022

Journal of medical genetics

Prospective validation of the BOADICEA multifactorial breast cancer risk prediction model in a large prospective cohort study.

01-12-2022

ESMO open

Complete genomic characterization in patients with cancer of unknown primary origin in routine diagnostics.

01-12-2022

Nature reviews. Cancer

Tumour avatars to model patients' responses to immunotherapy.

01-12-2022

Annals of oncology : official journal of the European Society for Medical Oncology

Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer.

01-12-2022

Gynecologic and obstetric investigation

Establishment of the Dutch Nationwide, Interdisciplinary Infrastructure and Biobank for Fundamental and Translational Ovarian Cancer Research: Archipelago of Ovarian Cancer Research.

01-12-2022

International journal of cancer

Survival after neoadjuvant/induction combination immunotherapy vs combination platinum-based chemotherapy for locally advanced (Stage III) urothelial cancer.

01-12-2022

Breast cancer research and treatment

Adjuvant aromatase inhibitor therapy and early markers for cardiovascular disease in breast cancer survivors.

01-12-2022

Neuro-oncology

Factors associated with health-related quality of life (HRQoL) deterioration in glioma patients during the progression-free survival period.

01-12-2022

Annals of oncology : official journal of the European Society for Medical Oncology

Management of toxicities from immunotherapy: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.

01-12-2022

Nature communications

Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential.

30-11-2022

Frontiers in pharmacology

SLC7A8 coding for LAT2 is associated with early disease progression in osteosarcoma and transports doxorubicin.

29-11-2022

eLife

Mother cells control daughter cell proliferation in intestinal organoids to minimize proliferation fluctuations.

29-11-2022

Sensors (Basel, Switzerland)

Electronic Nose Sensor Drift Affects Diagnostic Reliability and Accuracy of Disease-Specific Algorithms.

28-11-2022

Frontiers in genetics

DOT1L inhibition does not modify the sensitivity of cutaneous T cell lymphoma to pan-HDAC inhibitors in vitro.

26-11-2022

Cancers

Patterns of Hearing Loss in Irradiated Survivors of Head and Neck Rhabdomyosarcoma.

23-11-2022

Breast cancer research : BCR

Correction: PredictCBC-2.0: a contralateral breast cancer risk prediction model developed and validated in ~ 200,000 patients.

22-11-2022

Cell reports

DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability.

22-11-2022

Nature communications

Author Correction: Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.

21-11-2022

Cancers

Systemic Therapy in Advanced Nodular Melanoma versus Superficial Spreading Melanoma: A Nation-Wide Study of the Dutch Melanoma Treatment Registry.

19-11-2022

Biomolecules

E-Cadherin Expression Distinguishes Mouse from Human Hematopoiesis in the Basophil and Erythroid Lineages.

17-11-2022

International journal of cancer

Reply to: Comments on "Neoadjuvant/induction combination immunotherapy vs combination platinum-based chemotherapy for locally advanced (Stage III) urothelial cancer".

15-11-2022

World journal of gastrointestinal oncology

Missed colorectal cancers in a fecal immunochemical test-based screening program: Molecular profiling of interval carcinomas.

15-11-2022

Cell reports. Medicine

Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis.

15-11-2022

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of an ultra-high performance liquid chromatography coupled to tandem mass spectrometry method for the quantification of the antileishmanial drug paromomycin in human skin tissue.

15-11-2022

Cell reports. Medicine

Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer.

15-11-2022

Clinical cancer research : an official journal of the American Association for Cancer Research

PD-1T TILs as a Predictive Biomarker for Clinical Benefit to PD-1 Blockade in Patients with Advanced NSCLC.

14-11-2022

Cancers

Features on Endoscopy and MRI after Treatment with Contact X-ray Brachytherapy for Rectal Cancer: Explorative Results.

13-11-2022

Journal of plastic surgery and hand surgery

Surgical flap delay to allow primary transabdominal transplantation of extended rectus abdominis myocutaneous flaps in increasingly complex pelvic wound reconstructions.

08-11-2022

NPJ breast cancer

Deep learning for fully-automated nuclear pleomorphism scoring in breast cancer.

08-11-2022

BMJ open

Cohort profile: Risk and risk factors for female breast cancer after treatment for childhood and adolescent cancer: an internationally pooled cohort.

07-11-2022

The Journal of cell biology

Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin.

07-11-2022

Bio-protocol

An Unbiased CRISPR-Cas9 Screening Method for the Identification of Positive and Negative Regulatory Proteins of Cell Adhesion.

05-11-2022

Cancer research

The 5-Hydroxymethylcytosine Landscape of Prostate Cancer.

02-11-2022

Cancer discovery

UNCAN.eu, a European Initiative to UNderstand CANcer.

02-11-2022

Nature communications

MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling.

02-11-2022