Publications

Cell and tissue research

Radiation-induced apoptosis.

01-07-2000

Proceedings of the National Academy of Sciences of the United States of America

Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs.

20-06-2000

American journal of epidemiology

Reporting bias in case-control studies on induced abortion and breast cancer.

15-06-2000

Clinical pharmacology and therapeutics

Validation of techniques for the prediction of carboplatin exposure: application of Bayesian methods.

01-06-2000

British journal of clinical pharmacology

Evaluation of the autoinduction of ifosfamide metabolism by a population pharmacokinetic approach using NONMEM.

01-06-2000

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Phase I and pharmacokinetic study of oral paclitaxel.

01-06-2000

Patient education and counseling

Psychological distress two years after diagnosis of breast cancer: frequency and prediction.

01-06-2000

The Journal of cell biology

The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes.

15-05-2000

Cancer chemotherapy and pharmacology

Successful treatment with paclitaxel of a patient with metastatic extra-adrenal pheochromocytoma (paraganglioma). A case report and review of the literature.

10-05-2000

International journal of radiation biology

Increased risk of breast cancer following irradiation for Hodgkin's disease is not a result of ATM germline mutations.

01-05-2000

European journal of immunology

Tumor size at the time of adoptive transfer determines whether tumor rejection occurs.

01-05-2000

European journal of immunology

Tracing and characterization of the low-avidity self-specific T cell repertoire.

01-05-2000

Genes & development

Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum.

15-04-2000

Cancer journal (Sudbury, Mass.)

High-dose chemotherapy with peripheral blood progenitor cell transplantation in the adjuvant treatment of breast cancer.

01-04-2000

Cancer causes & control : CCC

Cancer risk associated with subfertility and ovulation induction: a review.

01-04-2000

Anti-cancer drugs

Docetaxel in 253 previously treated patients with progressive locally advanced or metastatic breast cancer: results of a compassionate use program in The Netherlands.

01-04-2000

Oncogene

The adenovirus E1A binding protein BS69 is a corepressor of transcription through recruitment of N-CoR.

16-03-2000

International journal of radiation oncology, biology, physics

A treatment planning method to correct dose distributions distorted by setup verification fields.

15-03-2000

The cancer journal from Scientific American

Translational research offers individually tailored treatments for cancer patients.

04-03-2000

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica

The bactericidal/permeability-increasing protein (BPI) is membrane-associated in azurophil granules of human neutrophils, and relocation occurs upon cellular activation.

01-03-2000

Drug metabolism and disposition: the biological fate of chemicals

The role of mdr1a P-glycoprotein in the biliary and intestinal secretion of doxorubicin and vinblastine in mice.

01-03-2000

Journal of cell science

Formation of hemidesmosome-like structures in the absence of ligand binding by the (alpha)6(beta)4 integrin requires binding of HD1/plectin to the cytoplasmic domain of the (beta)4 integrin subunit.

01-03-2000

Cancer chemotherapy and pharmacology

Pharmacokinetics and metabolism of docetaxel administered as a 1-h intravenous infusion.

09-02-2000

The Journal of clinical investigation

Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier.

01-02-2000

Fresenius' journal of analytical chemistry

Validated method for the determination of platinum from a liposomal source (SPI-77) in human plasma using graphite furnace Zeeman atomic absorption spectrometry.

01-02-2000

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Long-term risk of second malignancy in survivors of Hodgkin's disease treated during adolescence or young adulthood.

01-02-2000

American journal of human genetics

ATM-heterozygous germline mutations contribute to breast cancer-susceptibility.

01-02-2000

International journal of pharmaceutics

In vitro biocompatibility studies with the experimental anticancer agent BIBX1382BS.

25-01-2000

Journal of the National Cancer Institute

Physical activity and breast cancer risk in women aged 20-54 years.

19-01-2000

The Journal of cell biology

Induction of cell scattering by expression of beta1 integrins in beta1-deficient epithelial cells requires activation of members of the rho family of GTPases and downregulation of cadherin and catenin function.

13-12-1999

Journal of cell science

Chromatin-association of the Polycomb group protein BMI1 is cell cycle-regulated and correlates with its phosphorylation status.

01-12-1999

The EMBO journal

The modified base J is the target for a novel DNA-binding protein in kinetoplastid protozoans.

15-11-1999

Investigational new drugs

Pharmacokinetics and metabolism of the staurosporine analogue CGP 41 251 in mice.

11-11-1999

International journal of radiation oncology, biology, physics

Comparison of prostate cancer treatment in two institutions: a quality control study.

01-11-1999

Journal of cancer research and clinical oncology

A limited-sampling model for the pharmacokinetics of carboplatin administered in combination with paclitaxel.

01-11-1999

Analytical biochemistry

32P-postlabeling assay for the quantification of the major platinum-DNA adducts.

01-11-1999

The Journal of clinical investigation

Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure.

01-11-1999

Clinical cancer research : an official journal of the American Association for Cancer Research

Coadministration of oral cyclosporin A enables oral therapy with paclitaxel.

01-11-1999

Anti-cancer drugs

Compatibility and stability of aplidine, a novel marine-derived depsipeptide antitumor agent, in infusion devices, and its hemolytic and precipitation potential upon i.v. administration.

01-11-1999

International journal of radiation oncology, biology, physics

Dose-wall histograms and normalized dose-surface histograms for the rectum: a new method to analyze the dose distribution over the rectum in conformal radiotherapy.

01-11-1999

Journal of cell science

Partial rescue of epithelial phenotype in integrin beta4 null mice by a keratin-5 promoter driven human integrin beta4 transgene.

01-11-1999

The Journal of experimental medicine

Selective expansion of cross-reactive CD8(+) memory T cells by viral variants.

01-11-1999

Mechanisms of development

In vivo analysis of Frat1 deficiency suggests compensatory activity of Frat3.

01-11-1999

Biochimica et biophysica acta

CDK-independent activities of D type cyclins.

29-10-1999

Oncogene

Overexpression of Frat1 in transgenic mice leads to glomerulosclerosis and nephrotic syndrome, and provides direct evidence for the involvement of Frat1 in lymphoma progression.

28-10-1999

The Journal of cell biology

Binding of integrin alpha6beta4 to plectin prevents plectin association with F-actin but does not interfere with intermediate filament binding.

18-10-1999

Genes & development

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

15-10-1999

Clinical cancer research : an official journal of the American Association for Cancer Research

Rapid esterase-sensitive breakdown of polysorbate 80 and its impact on the plasma pharmacokinetics of docetaxel and metabolites in mice.

01-10-1999

Proceedings of the National Academy of Sciences of the United States of America

Mice without phosphatidylcholine transfer protein have no defects in the secretion of phosphatidylcholine into bile or into lung airspaces.

28-09-1999

Oncogene

Developmental defects and tumor predisposition in Rb mutant mice.

20-09-1999

Radiation-induced apoptosis.

Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs.

Reporting bias in case-control studies on induced abortion and breast cancer.

Validation of techniques for the prediction of carboplatin exposure: application of Bayesian methods.

Evaluation of the autoinduction of ifosfamide metabolism by a population pharmacokinetic approach using NONMEM.

Phase I and pharmacokinetic study of oral paclitaxel.

Psychological distress two years after diagnosis of breast cancer: frequency and prediction.

The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes.

Successful treatment with paclitaxel of a patient with metastatic extra-adrenal pheochromocytoma (paraganglioma). A case report and review of the literature.

Increased risk of breast cancer following irradiation for Hodgkin's disease is not a result of ATM germline mutations.

Tumor size at the time of adoptive transfer determines whether tumor rejection occurs.

Tracing and characterization of the low-avidity self-specific T cell repertoire.

Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum.

High-dose chemotherapy with peripheral blood progenitor cell transplantation in the adjuvant treatment of breast cancer.

Cancer risk associated with subfertility and ovulation induction: a review.

Docetaxel in 253 previously treated patients with progressive locally advanced or metastatic breast cancer: results of a compassionate use program in The Netherlands.

The adenovirus E1A binding protein BS69 is a corepressor of transcription through recruitment of N-CoR.

A treatment planning method to correct dose distributions distorted by setup verification fields.

Translational research offers individually tailored treatments for cancer patients.

The bactericidal/permeability-increasing protein (BPI) is membrane-associated in azurophil granules of human neutrophils, and relocation occurs upon cellular activation.

The role of mdr1a P-glycoprotein in the biliary and intestinal secretion of doxorubicin and vinblastine in mice.

Formation of hemidesmosome-like structures in the absence of ligand binding by the (alpha)6(beta)4 integrin requires binding of HD1/plectin to the cytoplasmic domain of the (beta)4 integrin subunit.

Pharmacokinetics and metabolism of docetaxel administered as a 1-h intravenous infusion.

Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier.

Validated method for the determination of platinum from a liposomal source (SPI-77) in human plasma using graphite furnace Zeeman atomic absorption spectrometry.

Long-term risk of second malignancy in survivors of Hodgkin's disease treated during adolescence or young adulthood.

ATM-heterozygous germline mutations contribute to breast cancer-susceptibility.

In vitro biocompatibility studies with the experimental anticancer agent BIBX1382BS.

Physical activity and breast cancer risk in women aged 20-54 years.

Induction of cell scattering by expression of beta1 integrins in beta1-deficient epithelial cells requires activation of members of the rho family of GTPases and downregulation of cadherin and catenin function.

Chromatin-association of the Polycomb group protein BMI1 is cell cycle-regulated and correlates with its phosphorylation status.

The modified base J is the target for a novel DNA-binding protein in kinetoplastid protozoans.

Pharmacokinetics and metabolism of the staurosporine analogue CGP 41 251 in mice.

Comparison of prostate cancer treatment in two institutions: a quality control study.

A limited-sampling model for the pharmacokinetics of carboplatin administered in combination with paclitaxel.

32P-postlabeling assay for the quantification of the major platinum-DNA adducts.

Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure.

Coadministration of oral cyclosporin A enables oral therapy with paclitaxel.

Compatibility and stability of aplidine, a novel marine-derived depsipeptide antitumor agent, in infusion devices, and its hemolytic and precipitation potential upon i.v. administration.

Dose-wall histograms and normalized dose-surface histograms for the rectum: a new method to analyze the dose distribution over the rectum in conformal radiotherapy.

Partial rescue of epithelial phenotype in integrin beta4 null mice by a keratin-5 promoter driven human integrin beta4 transgene.

Selective expansion of cross-reactive CD8(+) memory T cells by viral variants.

In vivo analysis of Frat1 deficiency suggests compensatory activity of Frat3.

CDK-independent activities of D type cyclins.

Overexpression of Frat1 in transgenic mice leads to glomerulosclerosis and nephrotic syndrome, and provides direct evidence for the involvement of Frat1 in lymphoma progression.

Binding of integrin alpha6beta4 to plectin prevents plectin association with F-actin but does not interfere with intermediate filament binding.

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

Rapid esterase-sensitive breakdown of polysorbate 80 and its impact on the plasma pharmacokinetics of docetaxel and metabolites in mice.

Mice without phosphatidylcholine transfer protein have no defects in the secretion of phosphatidylcholine into bile or into lung airspaces.

Developmental defects and tumor predisposition in Rb mutant mice.

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