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Jonkers
Jos Jonkers

Jos Jonkers

Group leader

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Jos Jonkers performed his PhD research (thesis: Identification and characterization of the Frat1 proto-oncogene, University of Amsterdam) and postdoctoral research in the group of Anton Berns at the NKI. In 2002, he visited the lab of Allan Bradley at the Sanger Institute to develop platforms for mouse array-CGH. He became an assistant professor at the NKI in 2003 and a permanent staff member in 2008. In 2012 he was elected to EMBO membership and appointed as head of the Division of Molecular Pathology at the NKI. In 2013, he was appointed as affiliate Professor at Leiden University, and in 2017, he was appointed as Senior Investigator at the Oncode Institute. His lab specializes in the genetic dissection of human BRCA-associated hereditary breast cancer and E-cadherin mutated invasive lobular breast cancer through the use of genetically engineered mouse models and patient-derived xenograft models, which are used for both basic and translational studies.


Fields of expertise

Breast cancer

Mouse models of human cancer

Functional cancer genomics

Work experience

2017 - present
Senior Investigator, Oncode Institute

2013 - present
Professor of Molecular Experimental Oncogenetics and Cancer Therapeutics, University of Leiden, The Netherlands

2012 - present
Managing Director of the Mouse Clinic for Cancer and Aging research (MCCA)

2012 - present
Senior Group Leader and Head of the Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

2008 - 2012
Group Leader (Associate Professor) and permanent staff member, Division of Molecular Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

2003 - 2008
Junior Group Leader (Assistant Professor), Division of Molecular Biology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

2002
Senior Research Associate in the laboratory of Allan Bradley, Wellcome Trust Sanger Institute, Hinxton, UK

1996 - 2002
Postdoctoral Fellow in the laboratory of Anton Berns, The Netherlands Cancer Institute, Amsterdam, The Netherlands

1990 - 1996
Ph.D. research in the laboratory of Anton Berns, The Netherlands Cancer Institute, Amsterdam, The Netherlands

Additional activities

  • Professor of Molecular Experimental Oncogenetics and Cancer Therapeutics, Leiden University
  • Senior Investigator, Oncode Institute
  • Scientific Director European Consortium of PDX models (EuroPDX)
  • Member European Molecular Biology Organization
  • Member Translational Advisory Committee OlympiA phase III breast cancer trial
  • Member Translational Research Committee BRAVO phase III breast cancer trial
  • Member Scientific Advisory Board of Artios Pharma
  • Member Scientific Advisory Board CRUK Beatson Institute
  • Member Scientific Advisory Board CRUK Manchester Institute
  • Member AACR Distinguished Lectureship in Breast Cancer Research Committee
  • Member AACR Publications Committee
  • Member Editorial Board BMC Genomics
  • Member Editorial Board International Journal of Cancer
  • Member Editorial Board Journal of Pathology
  • Member Editorial Board Molecular Cancer Research
  • Member Editorial Board Cancers

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