I divide my time at the NKI between treating cancer patients at the Antoni van Leeuwenhoek hospital and performing translational and laboratory science, where we explore the mechanisms underlying prostate cancer development and sensitivity to treatments. Our research has a focus on gene regulation in prostate cancer and the role of the tumor microenvironment in prostate cancer development. Tumor and blood samples from patients are the basis for our studies, while we validate our findings in various prostate cancer models. We aim to better understand the development of prostate cancer and factors involved in treatment resistance, which enables us to personalize treatment selection for patients.