Tumor organoids form 'training school' for T cells


'Real life' research model for improvement of personalized immunotherapy in cancer

Researchers from the Netherlands Cancer Institute and others have shown that it is possible to obtain immune cells (so-called killer T cells) from the bloodstream of a cancer patient and expand them in a dish together with a living piece of tumor from the same patient. Such a tumor piece is called a tumor organoid. The immune cells develop the ability to kill the tumor cells and to reduce organoid size, while leaving healthy control tissue of the same patient untouched.

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