Thesis defense Joppe Nieuwenhuis: A genetic peek into the cell

The connection between an individual's genetic makeup (genotype) and an individual's observable traits (phenotype) is often unclear. Generating mutations in haploid human cells is a powerful method to uncover new links between genes and phenotypes. Haploid cells contain just one copy of its genes. Netherlands Cancer Institute researcher Joppe Nieuwenhuis applied a genetic screening system based on haploid cells to find the first tubulin detyrosinating enzymes, which people have tried to identify since four decades. On Monday December 17^th he will defend his thesis. Goodluck Joppe!