He designed a statistical framework, based on copy number profiles, for finding peak regions on the genome that are likely to harbor both oncogenes and tumor suppressors for any given cancer type. Ewald van Dyk: 'If we consider only DNA copy number alterations, ignoring all other sources such as mutation data, we can already detect hundreds of such regions. One cannot help but wonder just how many genes are causally linked to cancer.'
Ewald van Dyk conducted his PhD research in the Lodewyk Wessel lab and is currently working as a postdoc in the Karin de Visser lab, unraveling mechanisms by which tumors affect the immune system.
When: Wednesday January 9th, 12.30 AM
Where: Delft Technical University
Thesis: Computational Analysis of Copy Number profiles of tumors
Supervisors: Lodewyk Wessels (NKI) and Marcel Reinders (Delft Technical University)