Aldo Spanjaard

I studied biomedical sciences at the University of Amsterdam. I performed my master internship in the group of Jannie Borst, Division of Immunology, Netherlands Cancer Institute, Ansterdam. Since March 2017, I continue as a PhD student at the same Institution in the newly formed Division of Tumor Biology and immunology in the group of Heinz Jacobs. Here, I will examine the sensitivity of cancer cells lacking specific (DNA) translesion synthesis (TLS) polymerases for alkylating agents. TLS polymerases can continue replication opposite a modified DNA templates. We hope that our insights improve chemotherapy and provide novel strategies for precision cancer medicine.