This website uses cookies

This websites contains videos from YouTube. This company uses cookies (third party cookies). If you do not want them to use these cookies, you can indicate so here. However, this does mean that you will not be able to watch videos on this website. We also make use of our own cookies in order to improve our website. We don't share our data with other parties. Which cookies are involved?

This website uses cookies to enable video and to improve the user experience. If you do not want to accept these cookies, indicate so here. Which cookies are involved?

Ga direct naar de inhoud, het hoofdmenu, het servicemenu of het zoekveld.


05Jun 2020

Back to Seminars overview

National seminar by Jurgen Marteijn

Jurgen Marteijn
Department of Molecular Genetics, Oncode Institute, Erasmus MC, Rotterdam, The Netherlands

The cellular response to DNA damage-induced Transcription stress

Friday, June 5, 2020
Piet Borst Auditorium, Netherlands Cancer Institute, Amsterdam

Host: Jacqueline Jacobs

Jurgen Marteijn
Unperturbed transcription by RNA polymerase II is crucial for proper cell function and tissue homeostasis. However, when the DNA template of RNA polymerase is damaged, this will interfere with transcription. These transcription-blocking DNA lesions can cause genome-instability and cellular dysfunction. My lab studies how cells cope with the severe consequences of transcription-blocking DNA damage by studying the effects of DNA damage on transcription and how these DNA lesions are repaired by transcription-coupled repair.

Share this page