This website uses cookies

This websites contains videos from YouTube. This company uses cookies (third party cookies). If you do not want them to use these cookies, you can indicate so here. However, this does mean that you will not be able to watch videos on this website. We also make use of our own cookies in order to improve our website. We don't share our data with other parties. Which cookies are involved?

This website uses cookies to enable video and to improve the user experience. If you do not want to accept these cookies, indicate so here. Which cookies are involved?

Ga direct naar de inhoud, het hoofdmenu, het servicemenu of het zoekveld.

Seminars

28Jun 2019

Back to Seminars overview

International seminar by James Haber

James Haber
Brandeis University, Waltham, United States

Genome Stability and Instability during Repair of a Broken Chromosome

Friday, June 28, 2019, 11.00 hrs
Piet Borst Auditorium  

Hosts     : Anna Gonzalez Manjon & Ruben Schep

Jim Haber
We are engaged in studying how breaks in the DNA double helix are repaired and in certain cellular processes that they initiate. Such DNA double strand breaks, or DSBs, can lead to chromosome instability and can be lethal if not repaired. DSBs may result from irradiation or mutagenic chemicals. They may also arise during DNA replication as a product of stalled replication forks and they can also arise in specialized processes such as mating type switching in yeast or during the process of creating immunoglobulins. Interest in DSBs also stems from the fact that DSBs sometimes result in aberrations such as chromosomal rearrangements which in some organisms can lead to the formation of cancers.

Share this page