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15Feb 2019

Back to Seminars overview

International seminar by Andrea Alimonti

Andrea Alimonti
Institute of Oncology Research, Bellinzona, Switzerland

Aberrant activation of the tumour immune response drives resistance to prostate cancer therapy

Friday, February 15, 2019, 11.00 hrs
Piet Borst Auditorium    
Host: René Bernards

Andrea Alimonti
My research is focused on the characterization of a novel type of cellular senescence response which is elicited by complete loss of the tumor suppressor PTEN, and on the identification of novel compounds with pro-senescence activity. My final aim is to develop the concept of pro-senescence therapy for cancer, from experimental evidences to clinic, investigating the efficacy of "pro-senescence" compounds in phase I clinical trials. This will also allow for the identification of senescence markers in human tumor samples to be used in clinic.

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