Publications

Experimental cell research

The cytoplasmic domain of alpha 6A integrin subunit is an in vitro substrate for protein kinase C.

Immunogenetics

A susceptibility gene for alveolar lung tumors in the mouse maps between Hsp70.3 and G7 within the H2 complex.

Cancer chemotherapy and pharmacology

Isolation, purification, and biological activity of mono- and dihydroxylated paclitaxel metabolites from human feces.

Biochimica et biophysica acta

Growth factor-like effects of lysophosphatidic acid, a novel lipid mediator.

30-12-1994

Prostaglandins

Radiation reduces cyclooxygenase activity in cultured human endothelial cells at low doses.

01-12-1994

The Journal of cell biology

The mucin epiglycanin on TA3/Ha carcinoma cells prevents alpha 6 beta 4-mediated adhesion to laminin and kalinin and E-cadherin-mediated cell-cell interaction.

01-12-1994

Genes & development

E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo.

15-11-1994

FEBS letters

The human MDR3 P-glycoprotein promotes translocation of phosphatidylcholine through the plasma membrane of fibroblasts from transgenic mice.

14-11-1994

Laboratory investigation; a journal of technical methods and pathology

Tissue distribution of the human MDR3 P-glycoprotein.

01-11-1994

International journal of radiation oncology, biology, physics

Evidence for a renovascular component in hypertensive patients with late radiation nephropathy.

15-10-1994

Lancet (London, England)

Oral contraceptives and risk of breast cancer in women aged 20-54 years. Netherlands Oral Contraceptives and Breast Cancer Study Group.

24-09-1994

The EMBO journal

Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice.

15-09-1994

The EMBO journal

Interaction of c-Myc with the pRb-related protein p107 results in inhibition of c-Myc-mediated transactivation.

01-09-1994

The Journal of biological chemistry

B cell antigen receptor stimulation induces formation of a Shc-Grb2 complex containing multiple tyrosine-phosphorylated proteins.

12-08-1994

The Journal of cell biology

Major histocompatibility complex class II molecules induce the formation of endocytic MIIC-like structures.

01-08-1994

Clinical otolaryngology and allied sciences

Communication, functional disorders and lifestyle changes after total laryngectomy.

01-08-1994

The Journal of cell biology

Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.

01-08-1994

British journal of cancer

Melphalan tissue concentrations in patients treated with regional isolated perfusion for melanoma of the lower limb.

01-07-1994

Pharmacy world & science : PWS

Bioanalysis and pharmacokinetics of (investigational) vinca alkaloids.

10-06-1994

The EMBO journal

Reconstitution of a surface transferrin binding complex in insect form Trypanosoma brucei.

01-06-1994

Cell

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs.

20-05-1994

Cell

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins.

20-05-1994

Oncogene

Kras-2 alleles, mutations, and lung tumor susceptibility in the mouse--an evaluation.

01-05-1994

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Leukemia risk following Hodgkin's disease: relation to cumulative dose of alkylating agents, treatment with teniposide combinations, number of episodes of chemotherapy, and bone marrow damage.

01-05-1994

Virology

Mutagenesis and characterization of a 41-kilobase-pair region of the pseudorabies virus genome: transcription map, search for virulence genes, and comparison with homologs of herpes simplex virus type 1.

01-05-1994

European journal of immunology

CD3 components at the surface of pro-T cells can mediate pre-T cell development in vivo.

European journal of immunology

Targeting major histocompatibility complex class II molecules to the cell surface by invariant chain allows antigen presentation upon recycling.

Experimental cell research

The alpha 6 beta 4 integrin is a receptor for both laminin and kalinin.

Genes & development

Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene.

Lancet (London, England)

Risk of endometrial cancer after tamoxifen treatment of breast cancer.

19-02-1994

The Journal of biological chemistry

cAMP abrogates the p21ras-mitogen-activated protein kinase pathway in fibroblasts.

04-02-1994

Molecular biology of the cell

Distinct and overlapping ligand specificities of the alpha 3A beta 1 and alpha 6A beta 1 integrins: recognition of laminin isoforms.

Annals of oncology : official journal of the European Society for Medical Oncology

Toxicity grading systems. A comparison between the WHO scoring system and the Common Toxicity Criteria when used for nausea and vomiting.

Radiation research

Ionizing radiation enhances platelet adhesion to the extracellular matrix of human endothelial cells by an increase in the release of von Willebrand factor.

Annals of oncology : official journal of the European Society for Medical Oncology

Intraperitoneal-administered carboplatin in patients with ovarian cancer; influence of a dwell-time on toxicity and response.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Second cancer risk following Hodgkin's disease: a 20-year follow-up study.

Annals of oncology : official journal of the European Society for Medical Oncology

The quality of life of long-term survivors of Hodgkin's disease.

Journal of cell science

Expression of the integrin alpha 6 beta 4 in peripheral nerves: localization in Schwann and perineural cells and different variants of the beta 4 subunit.

Journal of chromatography

Fully automated high-performance liquid chromatographic method for the determination of carzelesin (U-80,244) and metabolites (U-76,073 and U-76,074) in human plasma.

14-01-1994

Cancer chemotherapy and pharmacology

Validation of a limited sampling model for carboplatin in a high-dose chemotherapy combination.

Cancer chemotherapy and pharmacology

Pharmaceutical development of a parenteral lyophilized formulation of the novel indoloquinone antitumor agent EO9.

Cold Spring Harbor symposia on quantitative biology

Mouse model systems to study multistep tumorigenesis.

Cancer chemotherapy and pharmacology

The pharmacokinetics of reduced folates after intraperitoneal and intravenous administration of racemic [6S,R]-folinic acid.

Annals of oncology : official journal of the European Society for Medical Oncology

Etoposide, leucovorin, 5-fluorouracil (ELF) combination chemotherapy for advanced gastric cancer: experience with two treatment schedules incorporating intravenous or oral etoposide.

Cancer chemotherapy and pharmacology

Lithium pharmacokinetics during cisplatin-based chemotherapy: a case report.

Investigational new drugs

Pharmaceutical development of a parenteral formulation of the novel anti-tumor agent carzelesin (U-80,244).

Cancer chemotherapy and pharmacology

Plasma pharmacokinetics, tissue disposition, excretion and metabolism of vinleucinol in mice as determined by high-performance liquid chromatography.